European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

May

Artificial intelligence for thoracic radiology: from research tool to clinical practice Lucio Calandriello, Simon L.F. Walsh Eur Respir J, 57 (5) 2100625; 10.1183/13993003.00625-2021
Thoracic aortic aneurysms: expanding the potential cardiovascular consequences of obstructive sleep apnoea Luciano F. Drager, Miguel A. Martinez-Garcia Eur Respir J, 57 (5) 2004440; 10.1183/13993003.04440-2020
Cutting the fat: advances and challenges in sleep apnoea genetics Heming Wang, Matthew O. Goodman, Tamar Sofer, Susan Redline Eur Respir J, 57 (5) 2004644; 10.1183/13993003.04644-2020
Repeat bronchoalveolar lavage in idiopathic pulmonary fibrosis: proceed with caution? Mark G. Jones, Martin Kolb Eur Respir J, 57 (5) 2100691; 10.1183/13993003.00691-2021
Putting the spotlight on macrophage-derived cathepsin in the pathophysiology of obliterative bronchiolitis Olivier Brugiere, Stijn E. Verleden Eur Respir J, 57 (5) 2004607; 10.1183/13993003.04607-2020
Salvaging the endothelium in acute respiratory distress syndrome: a druggable intersection between TLR4 and NAD⁺ signalling Ji Young Lee, Reece P. Stevens, Marie Migaud, Troy Stevens Eur Respir J, 57 (5) 2004588; 10.1183/13993003.04588-2020
High eosinophil counts predict decline in FEV₁: results from the CanCOLD study Wan C. Tan, Jean Bourbeau, Gilbert Nadeau, Wendy Wang, Neil Barnes, Sarah H. Landis, Miranda Kirby, James C. Hogg, Don D. Sin Eur Respir J, 57 (5) 2000838; 10.1183/13993003.00838-2020
Validation of the Bronchiectasis Impact Measure (BIM): a novel patient-reported outcome measure Megan L. Crichton, Emily K. Dudgeon, Amelia Shoemark, James D. Chalmers Eur Respir J, 57 (5) 2003156; 10.1183/13993003.03156-2020
Development and validation of a deep learning algorithm detecting 10 common abnormalities on chest radiographs Ju Gang Nam, Minchul Kim, Jongchan Park, Eui Jin Hwang, Jong Hyuk Lee, Jung Hee Hong, Jin Mo Goo, Chang Min Park Eur Respir J, 57 (5) 2003061; 10.1183/13993003.03061-2020
Compassionate use of delamanid in adults and children for drug-resistant tuberculosis: 5-year update Sambuddha Ghosh, Lusine Breitscheidel, Natasa Lazarevic, Alexandra Martin, Jeffrey Hafkin, Norbert Hittel Eur Respir J, 57 (5) 2002483; 10.1183/13993003.02483-2020
Obstructive sleep apnoea and the progression of thoracic aortic aneurysm: a prospective cohort study Thomas Gaisl, Protazy Rejmer, Maurice Roeder, Patrick Baumgartner, Noriane A. Sievi, Sandra Siegfried, Simon F. Stämpfli, Robert Thurnheer, John R. Stradling, Felix C. Tanner, Malcolm Kohler Eur Respir J, 57 (5) 2003322; 10.1183/13993003.03322-2020
Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health Satu Strausz, Sanni Ruotsalainen, Hanna M. Ollila, Juha Karjalainen, Tuomo Kiiskinen, Mary Reeve, Mitja Kurki, Nina Mars, Aki S. Havulinna, Elina Luonsi, Dina Mansour Aly, Emma Ahlqvist, Maris Teder-Laving, Priit Palta, Leif Groop, Reedik Mägi, Antti Mäkitie, Veikko Salomaa, Adel Bachour, Tiinamaija Tuomi, Aarno Palotie, Tuula Palotie, Samuli Ripatti Eur Respir J, 57 (5) 2003091; 10.1183/13993003.03091-2020
Cough hypersensitivity and suppression in COPD Peter S.P. Cho, Hannah V. Fletcher, Irem S. Patel, Richard D. Turner, Caroline J. Jolley, Surinder S. Birring Eur Respir J, 57 (5) 2003569; 10.1183/13993003.03569-2020
The interrelatedness of chronic cough and chronic pain Johnmary T. Arinze, Katia M.C. Verhamme, Annemarie I. Luik, Bruno Stricker, Joyce B.J. van Meurs, Guy G. Brusselle Eur Respir J, 57 (5) 2002651; 10.1183/13993003.02651-2020
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis Nikhil Hirani, Alison C. MacKinnon, Lisa Nicol, Paul Ford, Hans Schambye, Anders Pedersen, Ulf J. Nilsson, Hakon Leffler, Tariq Sethi, Susan Tantawi, Lise Gravelle, Robert J. Slack, Ross Mills, Utsa Karmakar, Duncan Humphries, Fredrik Zetterberg, Lucy Keeling, Lyn Paul, Philip L. Molyneaux, Feng Li, Wendy Funston, Ian A. Forrest, A. John Simpson, Michael A. Gibbons, Toby M. Maher Eur Respir J, 57 (5) 2002559; 10.1183/13993003.02559-2020
Nitrogen dioxide increases the risk of mortality in idiopathic pulmonary fibrosis Hee-Young Yoon, Sun-Young Kim, Ok-Jin Kim, Jin Woo Song Eur Respir J, 57 (5) 2001877; 10.1183/13993003.01877-2020
Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use Natalia Hernandez-Pacheco, Susanne J. Vijverberg, Esther Herrera-Luis, Jiang Li, Yang Yie Sio, Raquel Granell, Almudena Corrales, Cyrielle Maroteau, Ryan Lethem, Javier Perez-Garcia, Niloufar Farzan, Katja Repnik, Mario Gorenjak, Patricia Soares, Leila Karimi, Maximilian Schieck, Lina Pérez-Méndez, Vojko Berce, Roger Tavendale, Celeste Eng, Olaia Sardon, Inger Kull, Somnath Mukhopadhyay, Munir Pirmohamed, Katia M.C. Verhamme, Esteban G. Burchard, Michael Kabesch, Daniel B. Hawcutt, Erik Melén, Uroš Potocnik, Fook Tim Chew, Kelan G. Tantisira, Steve Turner, Colin N. Palmer, Carlos Flores, Maria Pino-Yanes, Anke H. Maitland-van der Zee Eur Respir J, 57 (5) 2003388; 10.1183/13993003.03388-2020
Association between asthma control trajectories in preschoolers and disease remission Cristina Longo, Lucie Blais, Marni Brownell, Jacqueline M. Quail, Mohsen Sadatsafavi, Amélie Forget, Marc-André Turcot, Yao Nie, Wenbin Li, Hamid Tavakoli, Qier Tan, Yuxin Fan, Robert W. Platt, Francine M. Ducharme Eur Respir J, 57 (5) 2001897; 10.1183/13993003.01897-2020
TLR7/8 regulates type I and type III interferon signalling in rhinovirus 1b-induced allergic asthma Jasmin Krug, Alexander Kiefer, Julia Koelle, Tytti Vuorinen, Paraskevi Xepapadaki, Barbara Stanic, Mircea T. Chiriac, Mübeccel Akdis, Theodor Zimmermann, Nikolaos G. Papadopoulos, Susetta Finotto Eur Respir J, 57 (5) 2001562; 10.1183/13993003.01562-2020
Decreased IDO1-dependent tryptophan metabolism in aged lung during influenza Soo Jung Cho, Kyung Sook Hong, Edward Schenck, Stefi Lee, Rebecca Harris, Jianjun Yang, Augustine M.K. Choi, Heather Stout-Delgado Eur Respir J, 57 (5) 2000443; 10.1183/13993003.00443-2020
Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome Carmela Morrone, Natalia F. Smirnova, Aicha Jeridi, Nikolaus Kneidinger, Christine Hollauer, Jonas Christian Schupp, Naftali Kaminski, Dieter Jenne, Oliver Eickelberg, Ali Önder Yildirim Eur Respir J, 57 (5) 2001416; 10.1183/13993003.01416-2020
Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody Hector Quijada, Tadeo Bermudez, Carrie L. Kempf, Daniel G. Valera, Alexander N. Garcia, Sara M. Camp, Jin H. Song, Evelyn Franco, Jessica K. Burt, Belinda Sun, Joseph B. Mascarenhas, Kimberlie Burns, Amir Gaber, Radu C. Oita, Vivian Reyes Hernon, Christy Barber, Liliana Moreno-Vinasco, Xiaoguang Sun, Anne E. Cress, Diego Martin, Zhonglin Liu, Ankit A. Desai, Viswanathan Natarajan, Jeffrey R. Jacobson, Steven M. Dudek, Christian Bime, Saad Sammani, Joe G.N. Garcia Eur Respir J, 57 (5) 2002536; 10.1183/13993003.02536-2020
Two sides of the same coin? A review of the similarities and differences between idiopathic pulmonary fibrosis and rheumatoid arthritis-associated interstitial lung disease Scott Matson, Joyce Lee, Oliver Eickelberg Eur Respir J, 57 (5) 2002533; 10.1183/13993003.02533-2020
Effectiveness and outcomes of air travel-related TB incident follow-up: a systematic review Laura Maynard-Smith, Colin Stewart Brown, Ross Jeremy Harris, Peter Hodkinson, Surinder Tamne, Sarah Ruth Anderson, Dominik Zenner Eur Respir J, 57 (5) 2000013; 10.1183/13993003.00013-2020
Methods for studying pulmonary lymphatics Victor E. Maldonado-Zimbron, Jiwon Hong, Peter Russell, Natalie L. Trevaskis, John Albert Windsor, Anthony Ronald John Phillips Eur Respir J, 57 (5) 2004106; 10.1183/13993003.04106-2020
Eradication success for non-tuberculous mycobacteria in children with cystic fibrosis Dominic A. Hughes, Idan Bokobza, Siobhán B. Carr Eur Respir J, 57 (5) 2003636; 10.1183/13993003.03636-2020
Cannabis use and lung cancer: time to stop overlooking the problem? Léa Betser, Matthieu Glorion, Pierre Mordant, Caroline Caramella, Maria-Rosa Ghigna, Benjamin Besse, David Planchard, Jérome Le Pavec, Alain Chapelier, Sylvie Friard, Valérie Gounant, Yves Castier, Antonin Levy, Olaf Mercier, Dominique Fabre, Elie Fadel, Pauline Pradere Eur Respir J, 57 (5) 2004132; 10.1183/13993003.04132-2020
Same-day repeatability of fractional exhaled nitric oxide in severe asthma Ran Wang, Fahad Alahmadi, Robert Niven, Stephen J. Fowler Eur Respir J, 57 (5) 2003391; 10.1183/13993003.03391-2020
R-Crizotinib predisposes to and exacerbates pulmonary arterial hypertension in animal models Charifa Awada, Yann Grobs, Wen-Hui Wu, Karima Habbout, Charlotte Romanet, Sandra Breuils-Bonnet, Eve Tremblay, Sandra Martineau, Roxane Paulin, Sébastien Bonnet, Steeve Provencher, François Potus, Olivier Boucherat Eur Respir J, 57 (5) 2003271; 10.1183/13993003.03271-2020
Residential air pollution increases the risk for persistent pulmonary hypertension after pulmonary endarterectomy Katleen Swinnen, Esmée Bijnens, Lidia Casas, Tim S. Nawrot, Marion Delcroix, Rozenn Quarck, Catharina Belge Eur Respir J, 57 (5) 2002680; 10.1183/13993003.02680-2020
Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences Sheila K. Patel, Jennifer A. Juno, Wen Shi Lee, Kathleen M. Wragg, P. Mark Hogarth, Stephen J. Kent, Louise M. Burrell Eur Respir J, 57 (5) 2003730; 10.1183/13993003.03730-2020
Arterial vascular volume changes with haemodynamics in schistosomiasis-associated pulmonary arterial hypertension Farbod N. Rahaghi, Joan F. Hilton, Ricardo A. Corrêa, Camila Loureiro, Jaquelina S. Ota-Arakaki, Carlos G.Y. Verrastro, Michael H. Lee, Claudia Mickael, Pietro Nardelli, David A. Systrom, Aaron B. Waxman, George R. Washko, Raúl San José Estépar, Brian B. Graham, Rudolf K.F. Oliveira Eur Respir J, 57 (5) 2003914; 10.1183/13993003.03914-2020
Risk of acute arterial and venous thromboembolic events in eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome) Alessandra Bettiol, Renato Alberto Sinico, Franco Schiavon, Sara Monti, Enrica Paola Bozzolo, Franco Franceschini, Marcello Govoni, Claudio Lunardi, Giuseppe Guida, Giuseppe Lopalco, Giuseppe Paolazzi, Angelo Vacca, Gina Gregorini, Pietro Leccese, Matteo Piga, Fabrizio Conti, Paolo Fraticelli, Luca Quartuccio, Federico Alberici, Carlo Salvarani, Silvano Bettio, Simone Negrini, Carlo Selmi, Savino Sciascia, Gabriella Moroni, Loredana Colla, Carlo Manno, Maria Letizia Urban, Alfredo Vannacci, Maria Rosa Pozzi, Paolo Fabbrini, Stefano Polti, Mara Felicetti, Maria Rita Marchi, Roberto Padoan, Paolo Delvino, Roberto Caporali, Carlomaurizio Montecucco, Lorenzo Dagna, Adriana Cariddi, Paola Toniati, Silvia Tamanini, Federica Furini, Alessandra Bortoluzzi, Elisa Tinazzi, Lorenzo Delfino, Iuliana Badiu, Giovanni Rolla, Vincenzo Venerito, Florenzo Iannone, Alvise Berti, Roberto Bortolotti, Vito Racanelli, Guido Jeannin, Angela Padula, Alberto Cauli, Roberta Priori, Armando Gabrielli, Milena Bond, Martina Tedesco, Giulia Pazzola, Paola Tomietto, Marco Pellecchio, Chiara Marvisi, Federica Maritati, Alessandra Palmisano, Christian Dejaco, Johann Willeit, Stefan Kiechl, Iacopo Olivotto, Peter Willeit, Domenico Prisco, Augusto Vaglio, Giacomo Emmi Eur Respir J, 57 (5) 2004158; 10.1183/13993003.04158-2020
Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient Matthias Ochs, Sara Timm, Sefer Elezkurtaj, David Horst, Jenny Meinhardt, Frank L. Heppner, Steffen Weber-Carstens, Andreas C. Hocke, Martin Witzenrath Eur Respir J, 57 (5) 2004165; 10.1183/13993003.04165-2020
Increased detection of pulmonary tuberculosis amongst hospitalised inpatients during the COVID-19 pandemic Liang En Wee, Kenneth Choon Meng Goh, Edwin Philip Conceicao, Jamie Bee Xian Tan, Li-Hwei Sng, Indumathi Venkatachalam Eur Respir J, 57 (5) 2100616; 10.1183/13993003.00616-2021
Cochrane review update leaves big questions unanswered regarding vaping: implications for medical practitioners Kielan Darcy McAlinden, Kathryn Barnsley, Heinrich C. Weber, Greg Haug, Collin Chia, Mathew Suji Eapen, Sukhwinder Singh Sohal Eur Respir J, 57 (5) 2100022; 10.1183/13993003.00022-2021
Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with professional-collected nasal versus nasopharyngeal swab Andreas K. Lindner, Olga Nikolai, Chiara Rohardt, Susen Burock, Claudia Hülso, Alisa Bölke, Maximilian Gertler, Lisa J. Krüger, Mary Gaeddert, Frank Tobian, Federica Lainati, Joachim Seybold, Terry C. Jones, Jörg Hofmann, Jilian A. Sacks, Frank P. Mockenhaupt, Claudia M. Denkinger Eur Respir J, 57 (5) 2004430; 10.1183/13993003.04430-2020
Genetic polymorphisms, vitamin D binding protein and vitamin D deficiency in COVID-19 Marijn M. Speeckaert, Reinhart Speeckaert, Joris R. Delanghe Eur Respir J, 57 (5) 2004638; 10.1183/13993003.04638-2020
Genetic polymorphisms, vitamin D binding protein and vitamin D deficiency in COVID-19 Aduragbemi A. Faniyi, Sebastian T. Lugg, Sian E. Faustini, Craig Webster, Joanne E. Duffy, Martin Hewison, Adrian Shields, Peter Nightingale, Alex G. Richter, David R. Thickett Eur Respir J, 57 (5) 2100653; 10.1183/13993003.00653-2021