European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

December

Editorials

Current clinical management of smoke inhalation injuries: a reality check Arietta Spinou, Nikolaos G. Koulouris Eur Respir J, 52 (6) 1802163; 10.1183/13993003.02163-2018
The International Collaboration to Improve Respiratory Health in Children (INCIRCLE) ERS Clinical Research Collaboration Peter D. Sly, Zoltán Hantos Eur Respir J, 52 (6) 1801867; 10.1183/13993003.01867-2018
The European research collaboration for Children's Interstitial Lung Disease (ChILDEU) ERS Clinical Research Collaboration Steve Cunningham, Carlee Gilbert, Nico Schwerk Eur Respir J, 52 (6) 1801855; 10.1183/13993003.01855-2018
Inhaled corticosteroids in COPD: the final verdict is… Janice M. Leung, Don D. Sin Eur Respir J, 52 (6) 1801940; 10.1183/13993003.01940-2018
Triple therapy trials in COPD: a precision medicine opportunity Samy Suissa, Amnon Ariel Eur Respir J, 52 (6) 1801848; 10.1183/13993003.01848-2018
Letting the right one in: evaluating the generalisability of clinical trials Rahul Shrimanker, Richard Beasley, Ciléin Kearns Eur Respir J, 52 (6) 1802218; 10.1183/13993003.02218-2018
Dropping acid: why is cystic fibrosis mucus abnormal? Bruce K. Rubin, David J. Thornton Eur Respir J, 52 (6) 1802057; 10.1183/13993003.02057-2018
Targeting interleukin-13 in idiopathic pulmonary fibrosis: from promising path to dead end Marlies S. Wijsenbeek, Mirjam Kool, Vincent Cottin Eur Respir J, 52 (6) 1802111; 10.1183/13993003.02111-2018
Palliative care for patients with pulmonary fibrosis: symptom relief is essential Kathleen Lindell, Ganesh Raghu Eur Respir J, 52 (6) 1802086; 10.1183/13993003.02086-2018
New short regimens for latent tuberculosis treatment: safety first! Dick Menzies, Anete Trajman Eur Respir J, 52 (6) 1802180; 10.1183/13993003.02180-2018

ERS statement

ERS statement on harmonised standards for lung cancer registration and lung cancer services in Europe Anna L. Rich, David R. Baldwin, Paul Beckett, Thierry Berghmans, Jeanette Boyd, Corinne Faivre-Finn, Françoise Galateau-Salle, Fernando Gamarra, Bogdan Grigoriu, Niels-Christian G. Hansen, Georgia Hardavella, Erik Jakobsen, Dragana Jovanovic, Assia Konsoulova, Gilbert Massard, John McPhelim, Anne-Pascale Meert, Robert Milroy, Luciano Mutti, Marianne Paesmans, Michael D. Peake, Paul Martin Putora, Dirk K.M. de Ruysscher, Jean-Paul Sculier, Arnaud Schepereel, Dragan R. Subotic, Paul Van Schil, Torsten Gerriet Blum Eur Respir J, 52 (6) 1800610; 10.1183/13993003.00610-2018

Lung cancer

Systematic evaluation of the efficacy–effectiveness gap of systemic treatments in metastatic nonsmall cell lung cancer Christine M. Cramer-van der Welle, Bas J.M. Peters, Franz M.N.H. Schramel, Olaf H. Klungel, Harry J.M. Groen, Ewoudt M.W. van de Garde Eur Respir J, 52 (6) 1801100; 10.1183/13993003.01100-2018
Variable radiological lung nodule evaluation leads to divergent management recommendations Arjun Nair, Emily C. Bartlett, Simon L.F. Walsh, Athol U. Wells, Neal Navani, Georgia Hardavella, Sanjeev Bhalla, Lucio Calandriello, Anand Devaraj, Jin Mo Goo, Jeffrey S. Klein, Heber MacMahon, C.M. Schaefer-Prokop, Joon-Beom Seo, Nicola Sverzellati, Sujal R. Desai Eur Respir J, 52 (6) 1801359; 10.1183/13993003.01359-2018

Asthma

Randomised controlled trials in severe asthma: selection by phenotype or stereotype Thomas Brown, Thomas Jones, Kerry Gove, Clair Barber, Scott Elliott, Anoop Chauhan, Peter Howarth Eur Respir J, 52 (6) 1801444; 10.1183/13993003.01444-2018

Cystic fibrosis

Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH David B. Hill, Robert F. Long, William J. Kissner, Eyad Atieh, Ian C. Garbarine, Matthew R. Markovetz, Nicholas C. Fontana, Matthew Christy, Mehdi Habibpour, Robert Tarran, M. Gregory Forest, Richard C. Boucher, Brian Button Eur Respir J, 52 (6) 1801297; 10.1183/13993003.01297-2018

Interstitial lung diseases

SAR156597 in idiopathic pulmonary fibrosis: a phase 2 placebo-controlled study (DRI11772) Ganesh Raghu, Luca Richeldi, Bruno Crestani, Peter Wung, Raphael Bejuit, Corinne Esperet, Christian Antoni, Christina Soubrane Eur Respir J, 52 (6) 1801130; 10.1183/13993003.01130-2018
Safety of benzodiazepines and opioids in interstitial lung disease: a national prospective study Sabrina Bajwah, Joanna M. Davies, Hanan Tanash, David C. Currow, Adejoke O. Oluyase, Magnus Ekström Eur Respir J, 52 (6) 1801278; 10.1183/13993003.01278-2018

Tuberculosis

Short-course regimens of rifapentine plus isoniazid to treat latent tuberculosis infection in older Chinese patients: a randomised controlled study Lei Gao, Haoran Zhang, Henan Xin, Jianmin Liu, Shouguo Pan, Xiangwei Li, Ling Guan, Fei Shen, Zisen Liu, Dakuan Wang, Xueling Guan, Jiaoxia Yan, Hengjing Li, Boxuan Feng, Xuefang Cao, Yu Chen, Wei Cui, Zongde Zhang, Yu Ma, Xiaoyou Chen, Xinhua Zhou, Qi Jin Eur Respir J, 52 (6) 1801470; 10.1183/13993003.01470-2018
Estimating the prevalence of latent tuberculosis in a low-incidence setting: Australia Katie Dorothy Dale, James McCracken Trauer, Pete J. Dodd, Rein M.G.J. Houben, Justin Timothy Denholm Eur Respir J, 52 (6) 1801218; 10.1183/13993003.01218-2018
High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen Norbert Ndjeka, Kathryn Schnippel, Iqbal Master, Graeme Meintjes, Gary Maartens, Rodolfo Romero, Xavier Padanilam, Martin Enwerem, Sunitha Chotoo, Nalini Singh, Jennifer Hughes, Ebrahim Variava, Hannetjie Ferreira, Julian te Riele, Nazir Ismail, Erika Mohr, Nonkqubela Bantubani, Francesca Conradie Eur Respir J, 52 (6) 1801528; 10.1183/13993003.01528-2018
Tuberculosis in the European Union and European Economic Area: a survey of national tuberculosis programmes Simon M. Collin, Gerard de Vries, Knut Lönnroth, Giovanni Battista Migliori, Ibrahim Abubakar, Sarah R. Anderson, Dominik Zenner Eur Respir J, 52 (6) 1801449; 10.1183/13993003.01449-2018

Allergy and basic science

Innate lymphoid cells in the upper airways: importance of CD117 and IL-1RI expression Koen Van Crombruggen, Sylvie Taveirne, Gabriele Holtappels, Georges Leclercq, Claus Bachert Eur Respir J, 52 (6) 1800742; 10.1183/13993003.00742-2018

Reviews

Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis Mario Cazzola, Paola Rogliani, Luigino Calzetta, Maria Gabriella Matera Eur Respir J, 52 (6) 1801586; 10.1183/13993003.01586-2018
Inhaled corticosteroids in COPD: friend or foe? Alvar Agusti, Leonardo M. Fabbri, Dave Singh, Jørgen Vestbo, Bartolome Celli, Frits M.E. Franssen, Klaus F. Rabe, Alberto Papi Eur Respir J, 52 (6) 1801219; 10.1183/13993003.01219-2018

Series

What is early COPD and why is it important? Joan B. Soriano, Francesca Polverino, Borja G. Cosio Eur Respir J, 52 (6) 1801448; 10.1183/13993003.01448-2018

Research letters

The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model Martina Gentzsch, Deborah M. Cholon, Nancy L. Quinney, Susan E. Boyles, Mary E.B. Martino, Carla M.P. Ribeiro Eur Respir J, 52 (6) 1801133; 10.1183/13993003.01133-2018
Dramatic response of refractory sarcoidosis under ruxolitinib in a patient with associated JAK2-mutated polycythemia Cécile Rotenberg, Valérie Besnard, Pierre-Yves Brillet, Stéphane Giraudier, Hilario Nunes, Dominique Valeyre Eur Respir J, 52 (6) 1801482; 10.1183/13993003.01482-2018
Inhaled corticosteroid containing combinations and mortality in COPD Jørgen Vestbo, Leonardo Fabbri, Alberto Papi, Stefano Petruzzelli, Mario Scuri, Alessandro Guasconi, Stefano Vezzoli, Dave Singh Eur Respir J, 52 (6) 1801230; 10.1183/13993003.01230-2018
Exacerbations of severe asthma in patients treated with mepolizumab Rahul Shrimanker, Ian D. Pavord, Steve Yancey, Liam G. Heaney, Ruth H. Green, Peter Bradding, Beverley Hargadon, Chris E. Brightling, Andrew J. Wardlaw, Pranabashis Haldar Eur Respir J, 52 (6) 1801127; 10.1183/13993003.01127-2018
A systematic review of clinical trial registration in major respiratory journals 2010–2018 Nelli S.M. Suntila, Alexandria Smith, Yusuf Al-Dabbagh, James D. Chalmers Eur Respir J, 52 (6) 1801491; 10.1183/13993003.01491-2018
Determinants of diagnostic delay in chronic thromboembolic pulmonary hypertension: results from the European CTEPH Registry Frederikus A. Klok, Stefano Barco, Stavros V. Konstantinides, Philippe Dartevelle, Elie Fadel, David Jenkins, Nick H. Kim, Michael Madani, Hiromi Matsubara, Eckhard Mayer, Joanna Pepke-Zaba, Marion Delcroix, Irene M. Lang Eur Respir J, 52 (6) 1801687; 10.1183/13993003.01687-2018

Correspondence

Challenges in interpreting trends in testing for a₁-antitrypsin deficiency in COPD patients from UK primary care Daniel R. Morales Eur Respir J, 52 (6) 1801986; 10.1183/13993003.01986-2018
Challenges in interpreting trends in testing for a₁-antitrypsin deficiency in COPD patients from UK primary care Joan B. Soriano Eur Respir J, 52 (6) 1802064; 10.1183/13993003.02064-2018
Improving the management of spontaneous pneumothorax Uri Kartoun Eur Respir J, 52 (6) 1801857; 10.1183/13993003.01857-2018
Improving the management of spontaneous pneumothorax José M. Porcel Eur Respir J, 52 (6) 1801918; 10.1183/13993003.01918-2018

Author Correction

“Physical activity as a moderator for obstructive sleep apnoea and cardiometabolic risk in the EPISONO study.” Marcos Mônico-Neto, Hanna Karen Moreira Antunes, Ronaldo Vagner Thomatieli dos Santos, Vânia D'Almeida, Altay Alves Lino de Souza, Lia Rita Azeredo Bittencourt and Sergio Tufik. Eur Respir J 2018; 52: 1701972. Eur Respir J, 52 (6) 1751972; 10.1183/13993003.51972-2017