European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

August

Air pollution and COVID-19: clearing the air and charting a post-pandemic course: a joint workshop report of ERS, ISEE, HEI and WHO Zorana J. Andersen, Barbara Hoffmann, Lidia Morawska, Martin Adams, Eeva Furman, Arzu Yorgancioglu, Dan Greenbaum, Maria Neira, Bert Brunekreef, Francesco Forastiere, Mary B. Rice, François Wakenhut, Erika Coleen, Hanna Boogaard, Ulrike Gehring, Erik Melén, Brian Ward, Sara De Matteis Eur Respir J, 58 (2) 2101063; 10.1183/13993003.01063-2021
World Health Organization treatment outcome definitions for tuberculosis: 2021 update Nguyen Nhat Linh, Kerri Viney, Medea Gegia, Dennis Falzon, Philippe Glaziou, Katherine Floyd, Hazim Timimi, Nazir Ismail, Matteo Zignol, Tereza Kasaeva, Fuad Mirzayev Eur Respir J, 58 (2) 2100804; 10.1183/13993003.00804-2021
Real-life evidence in ERS clinical practice guidelines: from foes to friends Markus Fally, Blin Nagavci, Thomy Tonia, Maarten van den Berge, Andrew Bush, Christopher Brightling, Nicolas Roche Eur Respir J, 58 (2) 2101718; 10.1183/13993003.01718-2021
Phenotyping long COVID Robert Naeije, Sergio Caravita Eur Respir J, 58 (2) 2101763; 10.1183/13993003.01763-2021
The NIVO score: can it help to improve noninvasive ventilation in daily clinical practice? Judith Elshof, Marieke L. Duiverman, Peter J. Wijkstra Eur Respir J, 58 (2) 2100336; 10.1183/13993003.00336-2021
Phenotype–genotype associations in primary ciliary dyskinesia: where do we stand? Myrofora Goutaki, Eva S.L. Pedersen Eur Respir J, 58 (2) 2100392; 10.1183/13993003.00392-2021
Assessing pulmonary hypertension severity in lung disease is a key step to improving outcomes: embrace resistance and don't be pressurised to go with the flow David G. Kiely, Robin Condliffe Eur Respir J, 58 (2) 2102008; 10.1183/13993003.02008-2021
European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis Anne B. Chang, Rebecca Fortescue, Keith Grimwood, Efthymia Alexopoulou, Leanne Bell, Jeanette Boyd, Andrew Bush, James D. Chalmers, Adam T. Hill, Bulent Karadag, Fabio Midulla, Gabrielle B. McCallum, Zena Powell, Deborah Snijders, Woo-Jung Song, Thomy Tonia, Christine Wilson, Angela Zacharasiewicz, Ahmad Kantar Eur Respir J, 58 (2) 2002990; 10.1183/13993003.02990-2020
Effectiveness of a specialised breathlessness service for patients with advanced disease in Germany: a pragmatic fast-track randomised controlled trial (BreathEase) Michaela Schunk, Lien Le, Zulfiya Syunyaeva, Birgit Haberland, Susanne Tänzler, Ulrich Mansmann, Larissa Schwarzkopf, Hildegard Seidl, Sabine Streitwieser, Miriam Hofmann, Thomas Müller, Tobias Weiß, Philipp Morawietz, Eva Annette Rehfuess, Rudolf Maria Huber, Ursula Berger, Claudia Bausewein Eur Respir J, 58 (2) 2002139; 10.1183/13993003.02139-2020
Exercise-induced bronchoconstriction and bronchodilation: investigating the effects of age, sex, airflow limitation and FEV₁ Imran Satia, Eldar Priel, Baraa K. Al-Khazraji, Graham Jones, Andy Freitag, Paul M. O'Byrne, Kieran J. Killian Eur Respir J, 58 (2) 2004026; 10.1183/13993003.04026-2020
Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents Tom Ruffles, Christina J. Jones, Colin Palmer, Steve Turner, Jonathan Grigg, Roger Tavendale, Fiona Hogarth, Petra Rauchhaus, Kristina Pilvinyte, Romanie Hannah, Helen Smith, Roberta Littleford, Brian Lipworth, Somnath Mukhopadhyay Eur Respir J, 58 (2) 2004107; 10.1183/13993003.04107-2020
Chronic pulmonary aspergillosis: prevalence, favouring pulmonary diseases and prognosis Thomas Maitre, Jonathan Cottenet, Cendrine Godet, Adrien Roussot, Nafiz Abdoul Carime, Vichita Ok, Antoine Parrot, Philippe Bonniaud, Catherine Quantin, Jacques Cadranel Eur Respir J, 58 (2) 2003345; 10.1183/13993003.03345-2020
Adjunctive treatment with oral dexamethasone in non-ICU patients hospitalised with community-acquired pneumonia: a randomised clinical trial Esther Wittermans, Stefan M.T. Vestjens, Simone M.C. Spoorenberg, Willem L. Blok, Jan C. Grutters, Rob Janssen, Ger T. Rijkers, Frank W.J.M. Smeenk, G. Paul Voorn, Ewoudt M.W. van de Garde, Willem Jan W. Bos Eur Respir J, 58 (2) 2002535; 10.1183/13993003.02535-2020
Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease Ho Namkoong, Yosuke Omae, Takanori Asakura, Makoto Ishii, Shoji Suzuki, Kozo Morimoto, Yosuke Kawai, Katsura Emoto, Andrew J. Oler, Eva P. Szymanski, Mitsunori Yoshida, Shuichi Matsuda, Kazuma Yagi, Isano Hase, Tomoyasu Nishimura, Yuka Sasaki, Takahiro Asami, Tetsuya Shiomi, Hiroaki Matsubara, Hisato Shimada, Junko Hamamoto, Byung Woo Jhun, Su-Young Kim, Hee Jae Huh, Hong-Hee Won, Manabu Ato, Kenjiro Kosaki, Tomoko Betsuyaku, Koichi Fukunaga, Atsuyuki Kurashima, Hervé Tettelin, Hideki Yanai, Surakameth Mahasirimongkol, Kenneth N. Olivier, Yoshihiko Hoshino, Won-Jung Koh, Steven M. Holland, Katsushi Tokunaga, Naoki Hasegawa Eur Respir J, 58 (2) 1902269; 10.1183/13993003.02269-2019
Cardiopulmonary exercise capacity and limitations 3 months after COVID-19 hospitalisation Ingunn Skjørten, Odd Andre Wathne Ankerstjerne, Divna Trebinjac, Eivind Brønstad, Øystein Rasch-Halvorsen, Gunnar Einvik, Tøri Vigeland Lerum, Knut Stavem, Anne Edvardsen, Charlotte Björk Ingul Eur Respir J, 58 (2) 2100996; 10.1183/13993003.00996-2021
Exercise training in COPD: muscle O₂ transport plasticity Ryan M. Broxterman, Peter D. Wagner, Russell S. Richardson Eur Respir J, 58 (2) 2004146; 10.1183/13993003.04146-2020
The Noninvasive Ventilation Outcomes (NIVO) score: prediction of in-hospital mortality in exacerbations of COPD requiring assisted ventilation Tom Hartley, Nicholas D. Lane, John Steer, Mark W. Elliott, Milind P. Sovani, Helen Jane Curtis, Elizabeth R. Fuller, Patrick B. Murphy, Dinesh Shrikrishna, Keir E. Lewis, Neil R. Ward, Chris D. Turnbull, Nicholas Hart, Stephen C. Bourke Eur Respir J, 58 (2) 2004042; 10.1183/13993003.04042-2020
Phospholipase A2 receptor 1 promotes lung cell senescence and emphysema in obstructive lung disease Delphine Beaulieu, Aya Attwe, Marielle Breau, Larissa Lipskaia, Elisabeth Marcos, Emmanuelle Born, Jin Huang, Shariq Abid, Geneviève Derumeaux, Amal Houssaini, Bernard Maitre, Marine Lefevre, Nora Vienney, Philippe Bertolino, Sara Jaber, Hiba Noureddine, Delphine Goehrig, David Vindrieux, David Bernard, Serge Adnot Eur Respir J, 58 (2) 2000752; 10.1183/13993003.00752-2020
Topological data analysis reveals genotype–phenotype relationships in primary ciliary dyskinesia Amelia Shoemark, Bruna Rubbo, Marie Legendre, Mahmoud R. Fassad, Eric G. Haarman, Sunayna Best, Irma C.M. Bon, Joost Brandsma, Pierre-Regis Burgel, Gunnar Carlsson, Siobhan B. Carr, Mary Carroll, Matt Edwards, Estelle Escudier, Isabelle Honoré, David Hunt, Gregory Jouvion, Michel R. Loebinger, Bernard Maitre, Deborah Morris-Rosendahl, Jean-Francois Papon, Camille M. Parsons, Mitali P. Patel, N. Simon Thomas, Guillaume Thouvenin, Woolf T. Walker, Robert Wilson, Claire Hogg, Hannah M. Mitchison, Jane S. Lucas Eur Respir J, 58 (2) 2002359; 10.1183/13993003.02359-2020
Unsupervised phenotypic clustering for determining clinical status in children with cystic fibrosis Nicole Filipow, Gwyneth Davies, Eleanor Main, Neil J. Sebire, Colin Wallis, Felix Ratjen, Sanja Stanojevic Eur Respir J, 58 (2) 2002881; 10.1183/13993003.02881-2020
Serum and pulmonary uric acid in pulmonary arterial hypertension Laurent Savale, Satoshi Akagi, Ly Tu, Amélie Cumont, Raphaël Thuillet, Carole Phan, Benjamin Le Vely, Nihel Berrebeh, Alice Huertas, Xavier Jaïs, Vincent Cottin, Ari Chaouat, Cécile Tromeur, Athénaïs Boucly, Etienne Marie Jutant, Olaf Mercier, Elie Fadel, David Montani, Olivier Sitbon, Marc Humbert, Yuichi Tamura, Christophe Guignabert Eur Respir J, 58 (2) 2000332; 10.1183/13993003.00332-2020
Risk factors associated with the development of interstitial lung abnormalities Ivette Buendía-Roldán, Rosario Fernandez, Mayra Mejía, Fortunato Juarez, Gustavo Ramirez-Martinez, Eduardo Montes, Ana Karem S. Pruneda, Karen Martinez-Espinosa, Aime Alarcon-Dionet, Iliana Herrera, Carina Becerril, Leslie Chavez-Galan, Mario Preciado, Annie Pardo, Moisés Selman Eur Respir J, 58 (2) 2003005; 10.1183/13993003.03005-2020
Lung transplantation for sarcoidosis: outcome and prognostic factors Jérôme Le Pavec, Dominique Valeyre, Pierre Gazengel, Are M. Holm, Hans Henrik Schultz, Michael Perch, Aurélie Le Borgne, Martine Reynaud-Gaubert, Christiane Knoop, Laurent Godinas, Sandrine Hirschi, Vincent Bunel, Rosalia Laporta, Sergio Harari, Elodie Blanchard, Jesper M. Magnusson, Adrien Tissot, Jean-François Mornex, Clément Picard, Laurent Savale, Jean-François Bernaudin, Pierre-Yves Brillet, Hilario Nunes, Marc Humbert, Elie Fadel, Jens Gottlieb Eur Respir J, 58 (2) 2003358; 10.1183/13993003.03358-2020
Neutrophil dysfunction in bronchiectasis: an emerging role for immunometabolism Yan Hui Giam, Amelia Shoemark, James D. Chalmers Eur Respir J, 58 (2) 2003157; 10.1183/13993003.03157-2020
Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation William W. Busse, Monica Kraft, Klaus F. Rabe, Yamo Deniz, Paul J. Rowe, Marcella Ruddy, Mario Castro Eur Respir J, 58 (2) 2003393; 10.1183/13993003.03393-2020
Framework for the evaluation of new tests for tuberculosis infection Yohhei Hamada, Saskia den Boon, Daniela Maria Cirillo, Adam Penn-Nicholson, Morten Ruhwald, Dick Menzies, Olivia Oxlade, Dennis Falzon, Avinash Kanchar, Alexei Korobitsyn, Matteo Zignol, Alberto Matteelli, Tereza Kasaeva Eur Respir J, 58 (2) 2004078; 10.1183/13993003.04078-2020
Similarity network fusion for the integration of multi-omics and microbiomes in respiratory disease Jayanth Kumar Narayana, Micheál Mac Aogáin, Nur A'tikah Binte Mohamed Ali, Krasimira Tsaneva-Atanasova, Sanjay H. Chotirmall Eur Respir J, 58 (2) 2101016; 10.1183/13993003.01016-2021
Pulmonary vascular resistance predicts mortality in patients with pulmonary hypertension associated with interstitial lung disease: results from the COMPERA registry Karen M. Olsson, Marius M. Hoeper, Christine Pausch, Ekkehard Grünig, Doerte Huscher, David Pittrow, Stephan Rosenkranz, Henning Gall Eur Respir J, 58 (2) 2101483; 10.1183/13993003.01483-2021
Elevated pulmonary vascular resistance predicts mortality in COPD patients Katarina Zeder, Alexander Avian, Gerhard Bachmaier, Philipp Douschan, Vasile Foris, Teresa Sassmann, Natascha Troester, Luka Brcic, Michael Fuchsjaeger, Leigh Matthew Marsh, Bradley A. Maron, Horst Olschewski, Gabor Kovacs Eur Respir J, 58 (2) 2100944; 10.1183/13993003.00944-2021
Deconditioning as main mechanism of impaired exercise response in COVID-19 survivors Rocco Francesco Rinaldo, Michele Mondoni, Elena Maria Parazzini, Federica Pitari, Elena Brambilla, Simone Luraschi, Maurizio Balbi, Giuseppe Francesco Sferrazza Papa, Giovanni Sotgiu, Marco Guazzi, Fabiano Di Marco, Stefano Centanni Eur Respir J, 58 (2) 2100870; 10.1183/13993003.00870-2021
Hyperventilation as one of the mechanisms of persistent dyspnoea in SARS-CoV-2 survivors Justina Motiejunaite, Pauline Balagny, Florence Arnoult, Laurence Mangin, Catherine Bancal, Emmanuelle Vidal-Petiot, Martin Flamant, Guillaume Jondeau, Alain Cohen-Solal, Marie-Pia d'Ortho, Justine Frija-Masson Eur Respir J, 58 (2) 2101578; 10.1183/13993003.01578-2021
Intrapulmonary bronchopulmonary anastomoses in COVID-19 respiratory failure Csaba Galambos, Douglas Bush, Steven H. Abman Eur Respir J, 58 (2) 2004397; 10.1183/13993003.04397-2020
Impact of the revised definition of extensively drug-resistant tuberculosis Nicolas Veziris, Isabelle Bonnet, Florence Morel, Lorenzo Guglielmetti, Thomas Maitre, Laure Fournier Le Ray, Wladimir Sougakoff, Jérôme Robert, Alexandra Aubry Eur Respir J, 58 (2) 2100641; 10.1183/13993003.00641-2021
Performance of a digital signal processing algorithm for the accurate quantification of cough frequency Jaclyn A. Smith, Kimberley Holt, Rachel Dockry, Shilpi Sen, Kitty Sheppard, Philip Turner, Paul Czyzyk, Kevin McGuinness Eur Respir J, 58 (2) 2004271; 10.1183/13993003.04271-2020
Integrating haemodynamics identifies an extreme pulmonary hypertension phenotype William M. Oldham, Edward Hess, Stephen W. Waldo, Marc Humbert, Gaurav Choudhary, Bradley A. Maron Eur Respir J, 58 (2) 2004625; 10.1183/13993003.04625-2020
Dynamic compliance and reactance in older non-smokers with asthma and fixed airflow obstruction Timothy Durack, David G. Chapman, Sandra Rutting, Cindy Thamrin, Gregory G. King, Katrina O. Tonga Eur Respir J, 58 (2) 2004400; 10.1183/13993003.04400-2020
Home monitoring reduced short stay admissions in suspected COVID-19 patients: COVID-box project Ebru Dirikgil, Rick Roos, Geert H. Groeneveld, Christian Heringhaus, Anna V. Silven, Annelieke H.J. Petrus, Maria Villalobos-Quesada, Roula Tsonaka, Paul J.M. van der Boog, Ton J. Rabelink, Willem Jan W. Bos, Niels H. Chavannes, Douwe E. Atsma, Y.K. Onno Teng Eur Respir J, 58 (2) 2100636; 10.1183/13993003.00636-2021
Detection and characterisation of extracellular vesicles in exhaled breath condensate and sputum of COPD and severe asthma patients Donatella Lucchetti, Giuseppe Santini, Luigi Perelli, Claudio Ricciardi-Tenore, Filomena Colella, Nadia Mores, Giuseppe Macis, Andrew Bush, Alessandro Sgambato, Paolo Montuschi Eur Respir J, 58 (2) 2003024; 10.1183/13993003.03024-2020
SARS-CoV-2 infections in people with primary ciliary dyskinesia: neither frequent, nor particularly severe Eva S.L. Pedersen, Myrofora Goutaki, Amanda L. Harris, Lucy Dixon, Michele Manion, Bernhard Rindlisbacher, COVID-PCD patient advisory group, Jane S. Lucas, Claudia E. Kuehni Eur Respir J, 58 (2) 2004548; 10.1183/13993003.04548-2020
Asthma, COPD and SARS-CoV-2 infection (COVID-19): potential mechanistic insights Peter A.B. Wark, Prabuddha S. Pathinayake, Mathew Suji Eapen, Sukhwinder Singh Sohal Eur Respir J, 58 (2) 2100920; 10.1183/13993003.00920-2021
Biologics may have a beneficial effect in asthma patients with COVID-19 José L. Izquierdo, Joan B. Soriano Eur Respir J, 58 (2) 2101076; 10.1183/13993003.01076-2021
Comment on: Transcriptomic analysis of CFTR-impaired endothelial cells reveals a pro-inflammatory phenotype Fabrice Antigny, Hélène Le Ribeuz, Marc Humbert, David Montani Eur Respir J, 58 (2) 2101365; 10.1183/13993003.01365-2021
Endothelial CFTR dysfunction and its involvement in the pathogenesis of pulmonary arterial hypertension Mathias Declercq, Lucas Treps, Siham Bousfia, Peter Carmeliet, Peter Witters Eur Respir J, 58 (2) 2101645; 10.1183/13993003.01645-2021
Interleukin-6 and intrapulmonary shunt Francisco Perez-Vizcaino, Laura Moreno, José A. Lorente Eur Respir J, 58 (2) 2101292; 10.1183/13993003.01292-2021
Prevalence of pulmonary embolism on hospital admission in COVID-19 patients: is there a role for pre-test probability scores and home treatment? Angelo Porfidia, Enrico Pola, Roberto Pola Eur Respir J, 58 (2) 2100785; 10.1183/13993003.00785-2021
Prevalence of pulmonary embolism in patients with COVID-19 at the time of hospital admission and role for pre-test probability scores and home treatment Mitja Jevnikar, Olivier Sanchez, Marc Humbert, Florence Parent Eur Respir J, 58 (2) 2101033; 10.1183/13993003.01033-2021