European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

December

Evolving diagnostic techniques in mediastinal lymphadenopathy: is mediastinal cryobiopsy the new kid on the block?
Reinier R.L. Wener, Paul E. Van Schil
Eur Respir J, 58 (6) 2101496; 10.1183/13993003.01496-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Less is more? Antibiotic treatment duration for exacerbations of bronchiectasis
James D. Chalmers, Holly R. Keir
Eur Respir J, 58 (6) 2101416; 10.1183/13993003.01416-2021
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Using placebo-controlled trials to define predictors of future exacerbations in severe asthma patients
Andriana I. Papaioannou, Andreas Photiades, Mina Gaga
Eur Respir J, 58 (6) 2101702; 10.1183/13993003.01702-2021
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Identifying and addressing health inequalities in asthma care
Dermot Ryan, Ian Sabroe
Eur Respir J, 58 (6) 2101829; 10.1183/13993003.01829-2021
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Distinguishing causation from genetic correlation in a Mendelian randomisation framework
Dipender Gill, Stephen Burgess
Eur Respir J, 58 (6) 2101346; 10.1183/13993003.01346-2021
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Targeting AMPK and the Nrf2/HO-1 axis: a promising therapeutic strategy in acute lung injury
Stefan W. Ryter
Eur Respir J, 58 (6) 2102238; 10.1183/13993003.02238-2021
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ERS clinical practice guidelines on treatment of sarcoidosis
Robert P. Baughman, Dominique Valeyre, Peter Korsten, Alexander G. Mathioudakis, Wim A. Wuyts, Athol Wells, Paola Rottoli, Hiliaro Nunes, Elyse E. Lower, Marc A. Judson, Dominique Israel-Biet, Jan C. Grutters, Marjolein Drent, Daniel A. Culver, Francesco Bonella, Katerina Antoniou, Filippo Martone, Bernd Quadder, Ginger Spitzer, Blin Nagavci, Thomy Tonia, David Rigau, Daniel R. Ouellette
Eur Respir J, 58 (6) 2004079; 10.1183/13993003.04079-2020
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Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial
Jing Zhang, Jie-Ru Guo, Zan-Sheng Huang, Wan-Lei Fu, Xian-Li Wu, Na Wu, Wolfgang M. Kuebler, Felix J.F. Herth, Ye Fan
Eur Respir J, 58 (6) 2100055; 10.1183/13993003.00055-2021
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Chronic respiratory diseases are predictors of severe outcome in COVID-19 hospitalised patients: a nationwide study
Guillaume Beltramo, Jonathan Cottenet, Anne-Sophie Mariet, Marjolaine Georges, Lionel Piroth, Pascale Tubert-Bitter, Philippe Bonniaud, Catherine Quantin
Eur Respir J, 58 (6) 2004474; 10.1183/13993003.04474-2020
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Performance of Xpert MTB/RIF Ultra for tuberculosis diagnosis in the context of passive and active case finding
Belén Saavedra, Edson Mambuque, Dinis Nguenha, Neide Gomes, Shilzia Munguambe, Juan Ignacio García, Santiago Izco, Sozinho Acacio, Adrià Murias-Closas, Marta Cossa, Irene Losada, Hadrián Pernas-Pardavila, Laura Oliveras, Grant Theron, Alberto L. García-Basteiro
Eur Respir J, 58 (6) 2100257; 10.1183/13993003.00257-2021
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Feasibility of shortening intravenous antibiotic therapy for bronchiectasis based on bacterial load: a proof-of-concept randomised controlled trial
Pallavi Bedi, Manjit K. Cartlidge, Yang Zhang, Kim Turnbull, Samantha Donaldson, Andrea Clarke, Jane Crowe, Kadiga Campbell, Catriona Graham, Ruzanna Franguylan, Adriano G. Rossi, Adam T. Hill
Eur Respir J, 58 (6) 2004388; 10.1183/13993003.04388-2020
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Evolution of CT findings after anticoagulant treatment for acute pulmonary embolism in patients with and without an ultimate diagnosis of chronic thromboembolic pulmonary hypertension
Natalia J. Braams, Gudula J.A.M. Boon, Frances S. de Man, Josien van Es, Paul L. den Exter, Lucia J.M. Kroft, Ludo F.M. Beenen, Menno V. Huisman, Esther J. Nossent, Anco Boonstra, Anton Vonk Noordegraaf, Dieuwertje Ruigrok, Frederikus A. Klok, Harm Jan Bogaard, Lilian J. Meijboom
Eur Respir J, 58 (6) 2100699; 10.1183/13993003.00699-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Patient characteristics, biomarkers and exacerbation risk in severe, uncontrolled asthma
Monica Kraft, Guy Brusselle, J. Mark FitzGerald, Ian D. Pavord, Matthew Keith, Malin Fagerås, Esther Garcia Gil, Ian Hirsch, Mitchell Goldman, Gene Colice
Eur Respir J, 58 (6) 2100413; 10.1183/13993003.00413-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Socioeconomic biases in asthma control and specialist referral of possible severe asthma
Kjell Erik Julius Håkansson, Vibeke Backer, Charlotte Suppli Ulrik
Eur Respir J, 58 (6) 2100741; 10.1183/13993003.00741-2021
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COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy
Markus Weckmann, Thomas Bahmer, Jannie Marie Sand, Sarah Rank Rønnow, Martin Pech, Cornelis Vermeulen, Alen Faiz, Diana Julie Leeming, Morten Asser Karsdal, Lars Lunding, Brian George G. Oliver, Michael Wegmann, Gudrun Ulrich-Merzenich, Uwe R. Juergens, Jannis Duhn, Yves Laumonnier, Olga Danov, Katherina Sewald, Ulrich Zissler, Marnix Jonker, Inke König, Gesine Hansen, Erika von Mutius, Oliver Fuchs, Anna-Maria Dittrich, Bianca Schaub, Christine Happle, Klaus F. Rabe, Maarten van de Berge, Janette Kay Burgess, Matthias Volkmar Kopp
Eur Respir J, 58 (6) 2003969; 10.1183/13993003.03969-2020
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Kidney function and obstructive lung disease: a bidirectional Mendelian randomisation study
Sehoon Park, Soojin Lee, Yaerim Kim, Semin Cho, Kwangsoo Kim, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim
Eur Respir J, 58 (6) 2100848; 10.1183/13993003.00848-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis
Yoshio Nakahara, Naozumi Hashimoto, Koji Sakamoto, Atsushi Enomoto, Taylor S. Adams, Toyoharu Yokoi, Norihito Omote, Sergio Poli, Akira Ando, Keiko Wakahara, Atsushi Suzuki, Masahide Inoue, Akitoshi Hara, Yasuyuki Mizutani, Kazuyoshi Imaizumi, Tsutomu Kawabe, Ivan O. Rosas, Masahide Takahashi, Naftali Kaminski, Yoshinori Hasegawa
Eur Respir J, 58 (6) 2003397; 10.1183/13993003.03397-2020
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AICAR decreases acute lung injury by phosphorylating AMPK and upregulating heme oxygenase-1
Israr Ahmad, Adam Molyvdas, Ming-Yuan Jian, Ting Zhou, Amie M. Traylor, Huachun Cui, Gang Liu, Weifeng Song, Anupam Agarwal, Tamas Jilling, Saurabh Aggarwal, Sadis Matalon
Eur Respir J, 58 (6) 2003694; 10.1183/13993003.03694-2020
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A contemporary practical approach to the multidisciplinary management of unclassifiable interstitial lung disease
Christopher J. Ryerson, Tamera J. Corte, Jeffrey L. Myers, Simon L.F. Walsh, Sabina A. Guler
Eur Respir J, 58 (6) 2100276; 10.1183/13993003.00276-2021
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The effectiveness of contact investigation among contacts of tuberculosis patients: a systematic review and meta-analysis
Kavindhran Velen, Rashmi Vijay Shingde, Jennifer Ho, Greg James Fox
Eur Respir J, 58 (6) 2100266; 10.1183/13993003.00266-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Saliva molecular testing for SARS-CoV-2: simplifying the diagnosis without losing accuracy
Francesca Saluzzo, Paola Mantegani, Valeria Poletti de Chaurand, Federica Cugnata, Patrizia Rovere-Querini, Marta Cilla, Patrizia Paola Erba, Sara Racca, Cristina Tresoldi, Caterina Uberti-Foppa, Clelia Di Serio, Daniela Maria Cirillo
Eur Respir J, 58 (6) 2102099; 10.1183/13993003.02099-2021
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Outcomes over the first two years of treatment with mepolizumab in severe asthma
Lynn Elsey, Thomas Pantin, Leanne-Jo Holmes, Gael Tavernier, Stephen J. Fowler
Eur Respir J, 58 (6) 2101313; 10.1183/13993003.01313-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Epigenetic blood biomarkers of ageing and mortality in COPD
Ana I. Hernandez Cordero, Chen Xi Yang, Stephen Milne, Xuan Li, Zsuzsanna Hollander, Virginia Chen, Raymond Ng, Scott J. Tebbutt, Janice M. Leung, Don D. Sin
Eur Respir J, 58 (6) 2101890; 10.1183/13993003.01890-2021
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The prognostic role of matrix metalloproteinase-7 in scleroderma-associated interstitial lung disease
Scott M. Matson, Seoyeon J. Lee, Ryan A. Peterson, Natalia A. Achtar-Zadeh, Francesco Boin, Paul J. Wolters, Joyce S. Lee
Eur Respir J, 58 (6) 2101560; 10.1183/13993003.01560-2021
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Circulating fibrocytes as a new tool to predict lung cancer progression after surgery?
Pauline Henrot, Fabien Beaufils, Matthieu Thumerel, Edmée Eyraud, Augustin Boudoussier, Hugues Begueret, Elise Maurat, Pierre-Olivier Girodet, Roger Marthan, Patrick Berger, Isabelle Dupin, Maéva Zysman
Eur Respir J, 58 (6) 2101221; 10.1183/13993003.01221-2021
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Should diffusing capacity quality control be treated like other laboratory devices?
Jeffrey M. Haynes, Gregg L. Ruppel, David A. Kaminsky
Eur Respir J, 58 (6) 2102642; 10.1183/13993003.02642-2021
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Soluble VE-cadherin: not just a marker of endothelial permeability
Shi Qi Li, Ying Ni Lin, Qing Yun Li
Eur Respir J, 58 (6) 2102241; 10.1183/13993003.02241-2021
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Reply: Soluble VE-cadherin: not just a marker of endothelial permeability
Olfa Harki, Gilles Faury, Isabelle Vilgrain, Jean-Louis Pépin, Anne Briançon-Marjollet
Eur Respir J, 58 (6) 2102629; 10.1183/13993003.02629-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
CFTR in the regulation of pulmonary vascular tone and remodeling
Christoph Tabeling, Martin Witzenrath, Wolfgang M. Kuebler
Eur Respir J, 58 (6) 2101861; 10.1183/13993003.01861-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides