European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

March

Achoo, achis, ATCHIN! Vaccine you… Filipe Froes, Francesco Blasi, Antoni Torres Eur Respir J, 51 (3) 1702558; 10.1183/13993003.02558-2017
Reassessing Th1 versus Th17.1 in sarcoidosis: new tricks for old dogma Edward S. Chen Eur Respir J, 51 (3) 1800010; 10.1183/13993003.00010-2018
Location or origin? What is critical for macrophage propagation of lung fibrosis? Xiaofeng Zhou, Bethany B. Moore Eur Respir J, 51 (3) 1800103; 10.1183/13993003.00103-2018
AHRR hypomethylation, lung function, lung function decline and respiratory symptoms Jakob B. Kodal, Camilla J. Kobylecki, Signe Vedel-Krogh, Børge G. Nordestgaard, Stig E. Bojesen Eur Respir J, 51 (3) 1701512; 10.1183/13993003.01512-2017
Increased T-helper 17.1 cells in sarcoidosis mediastinal lymph nodes Caroline E. Broos, Laura L. Koth, Menno van Nimwegen, Johannes C.C.M. in ‘t Veen, Sandra M.J. Paulissen, Jan Piet van Hamburg, Jouke T. Annema, Roxane Heller-Baan, Alex Kleinjan, Henk C. Hoogsteden, Marlies S. Wijsenbeek, Rudi W. Hendriks, Bernt van den Blink, Mirjam Kool Eur Respir J, 51 (3) 1701124; 10.1183/13993003.01124-2017
CSF1R inhibition prevents radiation pulmonary fibrosis by depletion of interstitial macrophages Lydia Meziani, Michele Mondini, Benoît Petit, Alexandre Boissonnas, Vincent Thomas de Montpreville, Olaf Mercier, Marie-Catherine Vozenin, Eric Deutsch Eur Respir J, 51 (3) 1702120; 10.1183/13993003.02120-2017
Effect modification of perinatal exposure to air pollution and childhood asthma incidence Éric Lavigne, Marc-André Bélair, Daniel Rodriguez Duque, Minh T. Do, David M. Stieb, Perry Hystad, Aaron van Donkelaar, Randall V. Martin, Daniel L. Crouse, Eric Crighton, Hong Chen, Richard T. Burnett, Scott Weichenthal, Paul J. Villeneuve, Teresa To, Jeffrey R. Brook, Markey Johnson, Sabit Cakmak, Abdool S. Yasseen, Mark Walker Eur Respir J, 51 (3) 1701884; 10.1183/13993003.01884-2017
Mesenchymal stromal cell infusion modulates systemic immunological responses in stable COPD patients: a phase I pilot study Jesse Armitage, Dino B.A. Tan, Russel Troedson, Paul Young, Kay-vin Lam, Kathryn Shaw, Marian Sturm, Daniel J. Weiss, Yuben P. Moodley Eur Respir J, 51 (3) 1702369; 10.1183/13993003.02369-2017
First histopathological evidence of irreversible pulmonary vascular disease in dasatinib-induced pulmonary arterial hypertension Cécile Daccord, Igor Letovanec, Patrick Yerly, Jonathan Bloch, Adam Ogna, Laurent P. Nicod, John-David Aubert Eur Respir J, 51 (3) 1701694; 10.1183/13993003.01694-2017
Adverse respiratory effects of opioids for chronic breathlessness: learning lessons from chronic pain Kyle T.S. Pattinson, Matthew J. Rowland, Annabel H. Nickol, Jane Quinlan Eur Respir J, 51 (3) 1702531; 10.1183/13993003.02531-2017
New era for European Respiratory Society clinical practice guidelines: joining efficiency and high methodological standards Marc Miravitlles, Thomy Tonia, David Rigau, Nicolas Roche, Céline Genton, Valérie Vaccaro, Tobias Welte, Mina Gaga, Guy Brusselle Eur Respir J, 51 (3) 1800221; 10.1183/13993003.00221-2018
Contrary to popular belief, ventilator-associated lower respiratory tract infections are less common in immunocompromised patients Lieuwe D. Bos Eur Respir J, 51 (3) 1800228; 10.1183/13993003.00228-2018
The ROS controversy in hypoxic pulmonary hypertension revisited Sébastien Bonnet, Olivier Boucherat Eur Respir J, 51 (3) 1800276; 10.1183/13993003.00276-2018
Biomarkers of carcinogenesis and tumour growth in patients with cutaneous melanoma and obstructive sleep apnoea Fernando Santamaria-Martos, Ivan Benítez, Cristina Girón, Ferran Barbé, Miguel-Angel Martínez-García, Luis Hernández, Josep M. Montserrat, Eduardo Nagore, Antonio Martorell, Francisco Campos-Rodriguez, Jaime Corral, Valentin Cabriada, Jorge Abad, Olga Mediano, Maria F. Troncoso, Irene Cano-Pumarega, Ana Maria Fortuna Gutierrez, Trinidad Diaz-Cambriles, Maria Somoza-Gonzalez, Isaac Almendros, Ramon Farre, David Gozal, Manuel Sánchez-de-la-Torre Eur Respir J, 51 (3) 1701885; 10.1183/13993003.01885-2017
Sex differences in the associations of obstructive sleep apnoea with epidemiological factors Tianyi Huang, Brian M. Lin, Sarah C. Markt, Meir J. Stampfer, Francine Laden, Frank B. Hu, Shelley S. Tworoger, Susan Redline Eur Respir J, 51 (3) 1702421; 10.1183/13993003.02421-2017
Cost-effectiveness of KRAS, EGFR and ALK testing for decision making in advanced nonsmall cell lung carcinoma: the French IFCT-PREDICT.amm study Sandrine Loubière, Alexandre Drezet, Michèle Beau-Faller, Denis Moro-Sibilot, Sylvie Friard, Marie Wislez, Hélène Blons, Catherine Daniel, Virginie Westeel, Anne Madroszyk, Hervé Léna, Patrick Merle, Julien Mazières, Gérard Zalcman, Roger Lacave, Martine Antoine, Franck Morin, Pascale Missy, Fabrice Barlesi, Pascal Auquier, Jacques Cadranel Eur Respir J, 51 (3) 1701467; 10.1183/13993003.01467-2017
Comparison of different staging methods for COPD in predicting outcomes Tang-Hsiu Huang, Tzuen-Ren Hsiue, Sheng-Hsiang Lin, Xin-Ming Liao, Po-Lan Su, Chiung-Zuei Chen Eur Respir J, 51 (3) 1700577; 10.1183/13993003.00577-2017
Markers of cardiovascular autonomic dysfunction predict COPD in middle-aged subjects Fabrizio Ricci, Per Wollmer, Gunnar Engström, Artur Fedorowski, Viktor Hamrefors Eur Respir J, 51 (3) 1702481; 10.1183/13993003.02481-2017
Impact of immunosuppression on incidence, aetiology and outcome of ventilator-associated lower respiratory tract infections Anne-Sophie Moreau, Ignacio Martin-Loeches, Pedro Povoa, Jorge Salluh, Alejandro Rodriguez, Arnaud W. Thille, Emilio Diaz Santos, Elisa Vedes, Suzana Margareth Lobo, Bruno Mégarbane, Esperanza Molero Silvero, Luis Coelho, Laurent Argaud, Rafael Sanchez Iniesta, Julien Labreuche, Anahita Rouzé, Saad Nseir Eur Respir J, 51 (3) 1701656; 10.1183/13993003.01656-2017
Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension Oleg Pak, Susan Scheibe, Azadeh Esfandiary, Mareike Gierhardt, Akylbek Sydykov, Angela Logan, Athanasios Fysikopoulos, Florian Veit, Matthias Hecker, Florian Kroschel, Karin Quanz, Alexandra Erb, Katharina Schäfer, Mirja Fassbinder, Nasim Alebrahimdehkordi, Hossein A. Ghofrani, Ralph T. Schermuly, Ralf P. Brandes, Werner Seeger, Michael P. Murphy, Norbert Weissmann, Natascha Sommer Eur Respir J, 51 (3) 1701024; 10.1183/13993003.01024-2017
Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma F. Nicole Dijk, Chengjian Xu, Erik Melén, Anne-Elie Carsin, Asish Kumar, Ilja M. Nolte, Olena Gruzieva, Goran Pershagen, Neomi S. Grotenboer, Olga E.M. Savenije, Josep Maria Antó, Iris Lavi, Carlota Dobaño, Jean Bousquet, Pieter van der Vlies, Ralf J.P. van der Valk, Johan C. de Jongste, Martijn C. Nawijn, Stefano Guerra, Dirkje S. Postma, Gerard H. Koppelman Eur Respir J, 51 (3) 1701377; 10.1183/13993003.01377-2017
Safety and efficacy of pirfenidone in patients carrying telomerase complex mutation Aurélien Justet, Gabriel Thabut, Effrosyni Manali, Maria Molina Molina, Caroline Kannengiesser, Jacques Cadranel, Vincent Cottin, Anne Gondouin, Hilario Nunes, Eline Magois, Cécile Tromeur, Grégoire Prevot, Spyros Papiris, Sylvain Marchand-Adam, Anne Sophie Gamez, Martine Reynaud-Gaubert, Lidwine Wemeau, Bruno Crestani, Raphael Borie Eur Respir J, 51 (3) 1701875; 10.1183/13993003.01875-2017
Differential diagnosis between newly diagnosed asthma and COPD using exhaled breath condensate metabolomics: a pilot study Mauro Maniscalco, Debora Paris, Dominique J. Melck, Antonio Molino, Mauro Carone, Paolo Ruggeri, Gaetano Caramori, Andrea Motta Eur Respir J, 51 (3) 1701825; 10.1183/13993003.01825-2017
Pulmonary capillary recruitment in exercise and pulmonary hypertension David Langleben, Stylianos E. Orfanos Eur Respir J, 51 (3) 1702559; 10.1183/13993003.02559-2017
Pulmonary capillary recruitment in exercise and pulmonary hypertension Horst Olschewski, Gabor Kovacs, Philippe Herve Eur Respir J, 51 (3) 1800260; 10.1183/13993003.00260-2018
A well-designed/conducted study on alpha-1 antitrypsin epidemiology not quoted Ignacio Blanco Eur Respir J, 51 (3) 1702662; 10.1183/13993003.02662-2017
Asbestos-related lung cancers are rarely associated with ALK, ROS1 and RET rearrangements Marie Uguen, Jean-Dominique Dewitte, Brice Loddé, Pascale Marcorelles, Arnaud Uguen Eur Respir J, 51 (3) 1702605; 10.1183/13993003.02605-2017
ERJ March Podcast: World TB Day Eur Respir J, 51 (3) 18E5103; 10.1183/13993003.E5103-2018
Will regulatory issues continue to be a major barrier to access to bedaquiline and delamanid? Tiziana Masini, Janika Hauser, Rutendo Kuwana, Nguyen Nhat Linh, Ernesto Jaramillo Eur Respir J, 51 (3) 1702480; 10.1183/13993003.02480-2017
Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement Jakko van Ingen, Timothy Aksamit, Claire Andrejak, Erik C. Böttger, Emmanuelle Cambau, Charles L. Daley, David E. Griffith, Lorenzo Guglielmetti, Steven M. Holland, Gwen A. Huitt, Won-Jung Koh, Christoph Lange, Philip Leitman, Theodore K. Marras, Kozo Morimoto, Kenneth N. Olivier, Miguel Santin, Jason E. Stout, Rachel Thomson, Enrico Tortoli, Richard J. Wallace, Kevin L. Winthrop, Dirk Wagner Eur Respir J, 51 (3) 1800170; 10.1183/13993003.00170-2018
The World Health Organization global aDSM database: generating evidence on the safety of new treatment regimens for drug-resistant tuberculosis Christine M. Halleux, Dennis Falzon, Corinne Merle, Ernesto Jaramillo, Fuad Mirzayev, Piero Olliaro, Karin Weyer Eur Respir J, 51 (3) 1701643; 10.1183/13993003.01643-2017
Uptake of governmental social protection and financial hardship during drug-resistant tuberculosis treatment in Rio de Janeiro, Brazil William E. Rudgard, Nancy S. das Chagas, Regina Gayoso, Mauricio L. Barreto, Delia Boccia, Liam Smeeth, Laura C. Rodrigues, Knut Lönnroth, Elizabeth Williamson, Ethel L.N. Maciel Eur Respir J, 51 (3) 1800274; 10.1183/13993003.00274-2018
The World Health Organization standards for tuberculosis care and management Christopher Gilpin, Alexei Korobitsyn, Giovanni Battista Migliori, Mario C. Raviglione, Karin Weyer Eur Respir J, 51 (3) 1800098; 10.1183/13993003.00098-2018
The lower limit of normal versus a fixed ratio to assess airflow limitation: will the debate ever end? Lewis J. Smith Eur Respir J, 51 (3) 1800403; 10.1183/13993003.00403-2018
Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis A. Susanne Dittrich, Iris Kühbandner, Stefanie Gehrig, Verena Rickert-Zacharias, Matthew Twigg, Sabine Wege, Clifford C. Taggart, Felix Herth, Carsten Schultz, Marcus A. Mall Eur Respir J, 51 (3) 1701910; 10.1183/13993003.01910-2017
Bedaquiline and delamanid for the treatment of multidrug-resistant tuberculosis: a multicentre cohort study in Korea Cheon Tae Kim, Tae-Ok Kim, Hong-Joon Shin, Young Chun Ko, Yeong Hun Choe, Hak-Ryul Kim, Yong-Soo Kwon Eur Respir J, 51 (3) 1702467; 10.1183/13993003.02467-2017
Acute respiratory distress syndrome in mechanically ventilated patients with community-acquired pneumonia Catia Cilloniz, Miquel Ferrer, Adamanthia Liapikou, Carolina Garcia-Vidal, Albert Gabarrus, Adrian Ceccato, Jorge Puig de La Bellacasa, Francesco Blasi, Antoni Torres Eur Respir J, 51 (3) 1702215; 10.1183/13993003.02215-2017
Laboratory-confirmed respiratory infections as triggers for acute myocardial infarction and stroke: a self-controlled case series analysis of national linked datasets from Scotland Charlotte Warren-Gash, Ruth Blackburn, Heather Whitaker, Jim McMenamin, Andrew C. Hayward Eur Respir J, 51 (3) 1701794; 10.1183/13993003.01794-2017
Young and middle-aged adults with airflow limitation according to lower limit of normal but not fixed ratio have high morbidity and poor survival: a population-based prospective cohort study Yunus Çolak, Shoaib Afzal, Børge G. Nordestgaard, Jørgen Vestbo, Peter Lange Eur Respir J, 51 (3) 1702681; 10.1183/13993003.02681-2017
Development and feasibility of an eHealth tool for idiopathic pulmonary fibrosis Catharina C. Moor, Mirjam J.G. van Manen, Nelleke C. Tak, Esther van Noort, Marlies S. Wijsenbeek Eur Respir J, 51 (3) 1702508; 10.1183/13993003.02508-2017
Are inhaled corticosteroids prescribed rationally in primary ciliary dyskinesia? Eleonora Dehlink, Charlotte Richardson, Gemma Marsh, Kiralie Lee, Angela Jamalzadeh, Andrew Bush, Claire Hogg, Siobhán B. Carr Eur Respir J, 51 (3) 1702221; 10.1183/13993003.02221-2017
Safety and efficacy of exposure to bedaquiline-delamanid in multidrug-resistant tuberculosis: a case series from France and Latvia Lorenzo Guglielmetti, Linda Barkane, Damien Le Dû, Dhiba Marigot-Outtandy, Jérôme Robert, Nicolas Veziris, Yazdan Yazdanpanah, Liga Kuksa, Eric Caumes, Mathilde Fréchet-Jachym Eur Respir J, 51 (3) 1702550; 10.1183/13993003.02550-2017
Xpert MTB/RIF as add-on test to microscopy in a low tuberculosis incidence setting Giorgia Sulis, Angelica Agliati, Gabriele Pinsi, Giordano Bozzola, Pierfranco Foccoli, Maurizio Gulletta, Silvio Caligaris, Lina R. Tomasoni, Issa El-Hamad, Alberto Matteelli Eur Respir J, 51 (3) 1702345; 10.1183/13993003.02345-2017
Hearing loss with kanamycin treatment for multidrug-resistant tuberculosis in Bangladesh Scott K. Heysell, Shahriar Ahmed, Md. Toufiq Rahman, Md. Wahiduzzaman Akhanda, A. Tucker Gleason, Andrew Ebers, Eric R. Houpt, Sayera Banu Eur Respir J, 51 (3) 1701778; 10.1183/13993003.01778-2017
Cross border, highly individualised treatment of a patient with challenging extensively drug-resistant tuberculosis Onno W. Akkerman, Floris Grasmeijer, Wiel C.M. de Lange, Huib A.M. Kerstjens, Gerard de Vries, Mathieu S. Bolhuis, Jan-Willem Alffenaar, Henderik W. Frijlink, Grace Smith, Roger Gajraj, Rina de Zwaan, Paul Hagedoorn, Martin Dedicoat, Dick van Soolingen, Tjip S. van der Werf Eur Respir J, 51 (3) 1702490; 10.1183/13993003.02490-2017
Low prevalence of fluoroquinolone resistance among patients with tuberculosis in the Philippines: results of a national survey Dodge R. Lim, Anna S. Dean, Mary Rosary Taguinod-Santiago, Angeli Borbe-Reyes, Andrea Maurizio Cabibbe, Matteo Zignol, Ramon P. Basilio, Anna Marie Celina Garfin, Maria Cecilia G. Ama Eur Respir J, 51 (3) 1702571; 10.1183/13993003.02571-2017
T-cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation Munyaradzi Musvosvi, Darragh Duffy, Elizabeth Filander, Hadn Africa, Simbarashe Mabwe, Lungisa Jaxa, Nicole Bilek, Alba Llibre, Vincent Rouilly, Mark Hatherill, Matthew Albert, Thomas J. Scriba, Elisa Nemes Eur Respir J, 51 (3) 1800153; 10.1183/13993003.00153-2018
Risk assessment in pulmonary arterial hypertension Marius M. Hoeper, David Pittrow, Christian Opitz, J. Simon R. Gibbs, Stephan Rosenkranz, Ekkehard Grünig, Karen M. Olsson, Doerte Huscher Eur Respir J, 51 (3) 1702606; 10.1183/13993003.02606-2017
Risk assessment in pulmonary arterial hypertension Athénaïs Boucly, Jason Weatherald, Marc Humbert, Olivier Sitbon Eur Respir J, 51 (3) 1800279; 10.1183/13993003.00279-2018
Impact of processing technique on bronchoalveolar lavage cellular analysis Leila Barss, Kristin L. Fraser, Margaret M. Kelly, Kerri A. Johannson Eur Respir J, 51 (3) 1701769; 10.1183/13993003.01769-2017
Renal Fanconi syndrome with meropenem-containing regimen in drug-resistant tuberculosis Simon Tiberi, Marie-Christine Payen, Giovanni Sotgiu, Lia D'Ambrosio, Rosella Centis, Jan-Willem Alffenaar, Giovanni Battista Migliori Eur Respir J, 51 (3) 1702187; 10.1183/13993003.02187-2017
Closing the gap in surveillance of tuberculosis and HIV co-infection, and the need for clinician–public health alliances Gerard de Vries, Susan van den Hof, Eline Op de Coul, Reinout van Crevel Eur Respir J, 51 (3) 1702671; 10.1183/13993003.02671-2017
Eligibility for the shorter regimen for multidrug-resistant tuberculosis in Mexico Marcela Munoz-Torrico, Miguel Angel Salazar, Miriam de Jesús Mohedano Millán, Jose A. Martínez Orozco, Luis A. Narvaez Diaz, Mariela Segura del Pilar, Dina Visca, Lia D'Ambrosio, Rosella Centis, Giovanni Battista Migliori Eur Respir J, 51 (3) 1702267; 10.1183/13993003.02267-2017
Pragmatic tuberculosis prevention policies for primary care in low- and middle-income countries Matthew J. Saunders, Marco A. Tovar, Sumona Datta, Benjamin E.W. Evans, Tom Wingfield, Carlton A. Evans Eur Respir J, 51 (3) 1800315; 10.1183/13993003.00315-2018