October

Blueprint for harmonising unstandardised disease registries to allow federated data analysis: prepare for the future Johannes A. Kroes, Aruna T. Bansal, Emmanuelle Berret, Nils Christian, Andreas Kremer, Anna Alloni, Matteo Gabetta, Chris Marshall, Scott Wagers, Ratko Djukanovic, Celeste Porsbjerg, Dominique Hamerlijnck, Olivia Fulton, Anneke ten Brinke, Elisabeth H. Bel, Jacob K. Sont ERJ Open Res, 8 (4) 00168-2022; 10.1183/23120541.00168-2022
Complete response to anti-interleukin-5 biologics in a real-life setting: results from the nationwide Danish Severe Asthma Register Marianne Baastrup Soendergaard, Susanne Hansen, Anne-Sofie Bjerrum, Ole Hilberg, Sofie Lock-Johansson, Kjell Erik Julius Håkansson, Truls Sylvan Ingebrigtsen, Claus Rikard Johnsen, Linda Makowska Rasmussen, Anna von Bülow, Karin Dahl Assing, Johannes Martin Schmid, Charlotte Suppli Ulrik, Celeste Porsbjerg ERJ Open Res, 8 (4) 00238-2022; 10.1183/23120541.00238-2022
Vasoreactive phenotype in children with pulmonary arterial hypertension and syncope Alexandra N. Linder, Jill Hsia, Sheila V. Krishnan, Erika B. Rosenzweig, Usha S. Krishnan ERJ Open Res, 8 (4) 00223-2022; 10.1183/23120541.00223-2022
Evaluation of aerosol drug delivery with concurrent low- and high-flow nasal oxygen Barry Murphy, Marc Mac Giolla Eain, Mary Joyce, James B. Fink, Ronan MacLoughlin ERJ Open Res, 8 (4) 00220-2022; 10.1183/23120541.00220-2022
Associations of influenza vaccination with severity of immune-related adverse events in patients with advanced thoracic cancers on immune checkpoint inhibitors Emily Pei-Ying Lin, Li-Ching Huang, Jennifer Whisenant, Sally York, Travis Osterman, Jennifer Lewis, Wade Iams, Emily Skotte, Amanda Cass, Chih-Yuan Hsu, Yu Shyr, Leora Horn ERJ Open Res, 8 (4) 00684-2021; 10.1183/23120541.00684-2021
Respiratory healthcare professionals’ views on long-term recommendations of interventions to prevent acute respiratory illnesses after the COVID-19 pandemic Karin Yaacoby-Bianu, Galit Livnat, James D. Chalmers, Michal Shteinberg ERJ Open Res, 8 (4) 00114-2022; 10.1183/23120541.00114-2022
Heightened ventilatory response during stair climbing in individuals with dysfunctional breathing Karina Siewers, Emil Walsted, Bishmann Manivannan, Christopher Warren, Colm McCabe, James H. Hull ERJ Open Res, 8 (4) 00285-2022; 10.1183/23120541.00285-2022
Air quality in Mexico City during the COVID-19 lockdown possibly decreased COPD exacerbations Francisco Montiel-Lopez, Daniela Rodríguez-Ramírez, Maricruz Cassou-Martínez, María Cristina Miranda-Márquez, Claudia González-González, Raúl H. Sansores, María Eugenia Mayar-Maya, Rogelio Pérez-Padilla, Robinson Emmanuel Robles-Hernández, Ireri Thirion-Romero, Oliver Pérez-Bautista, Alejandra Ramírez-Venegas ERJ Open Res, 8 (4) 00183-2022; 10.1183/23120541.00183-2022
It is time to end our love affair with short-acting ß₂-agonists in asthma Michael G. Crooks, Shoaib Faruqi ERJ Open Res, 8 (4) 00353-2022; 10.1183/23120541.00353-2022
Heterogeneity in the use of biologics for severe asthma in Europe: a SHARP ERS study Anne-Noelle Frix, Liam G. Heaney, Barbro Dahlén, Florin Mihaltan, Svetlana Sergejeva, Sanja Popovic-Grle, Vratislav Sedlak, Lauri Lehtimäki, Arnaud Bourdin, Stephanie Korn, Eleftherios Zervas, Zsuzsanna Csoma, Dora Lúðvíksdóttir, Marcus Butler, Giorgio Walter Canonica, Ineta Grisle, Kristina Bieksiene, Anneke Ten Brinke, Piotr Kuna, Claudia Chaves Loureiro, Natalia M. Nenasheva, Zorica Lazic, Sabina S?krgat, David Ramos-Barbon, Joerg Leuppi, Bilun Gemicioglu, Apostolos Bossios, Celeste M. Porsbjerg, Elisabeth H. Bel, Ratko Djukanovic, Renaud Louis ERJ Open Res, 8 (4) 00273-2022; 10.1183/23120541.00273-2022
Treatment with interleukin (IL)-5/IL-5 receptor antibodies in patients with severe eosinophilic asthma and COPD Nora Drick, Jan Fuge, Benjamin Seeliger, Milan Speth, Jens Vogel-Claussen, Tobias Welte, Hendrik Suhling ERJ Open Res, 8 (4) 00207-2022; 10.1183/23120541.00207-2022
Mortality associated with metabolic syndrome in people with COPD managed in primary care Urvee Karsanji, Rachael A. Evans, Jennifer K. Quint, Kamlesh Khunti, Claire A. Lawson, Emily Petherick, Neil J. Greening, Sally J. Singh, Matthew Richardson, Michael C. Steiner ERJ Open Res, 8 (4) 00211-2022; 10.1183/23120541.00211-2022
Haemodynamic effects of initial combination therapy in pulmonary arterial hypertension: a systematic review and meta-analysis Ioannis T. Farmakis, Elena Vrana, Sophia-Anastasia Mouratoglou, Stefanos Zafeiropoulos, Stavros Zanos, George Giannakoulas ERJ Open Res, 8 (4) 00313-2022; 10.1183/23120541.00313-2022
Randomised controlled trial of first-line tyrosine-kinase inhibitor (TKI) versus intercalated TKI with chemotherapy for EGFR-mutated nonsmall cell lung cancer Rolof G.P. Gijtenbeek, Vincent van der Noort, Joachim G.J.V. Aerts, Jeske A. Staal-van den Brekel, Egbert F. Smit, Frans H. Krouwels, Frank A. Wilschut, T. Jeroen N. Hiltermann, Wim Timens, Ed Schuuring, Joost D.J. Janssen, Martijn Goosens, Paul M. van den Berg, A. Joop de Langen, Jos A. Stigt, Ben E.E.M. van den Borne, Harry J.M. Groen, Wouter H. van Geffen, Anthonie J. van der Wekken ERJ Open Res, 8 (4) 00239-2022; 10.1183/23120541.00239-2022
Infant tidal flow–volume parameters and arousal state Karen Eline Stensby Bains, Martin Färdig, Hrefna Katrín Gudmundsdóttir, Catarina Almqvist, Gunilla Hedlin, Live S. Nordhagen, Eva M. Rehbinder, Håvard O. Skjerven, Cilla Söderhäll, Riyas Vettukattil, Björn Nordlund, Karin C. Lødrup Carlsen ERJ Open Res, 8 (4) 00163-2022; 10.1183/23120541.00163-2022
Clinical application of oscillometry in respiratory diseases: an impulse oscillometry registry Xiaolin Liang, Jinping Zheng, Yi Gao, Zhe Zhang, Wen Han, Jing Du, Yong Lu, Li Chen, Tao Wang, Jinming Liu, Gang Huang, Bingrong Zhao, Guihua Zhao, Xuhua Zhang, Yi Peng, Xin Chen, Ning Zhou ERJ Open Res, 8 (4) 00080-2022; 10.1183/23120541.00080-2022
Body mass index increase: a risk factor for forced expiratory volume in 1 s decline for overweight and obese adults with asthma Nicolás Bermúdez Barón, Hannu Kankaanranta, Linnea Hedman, Martin Andersson, Caroline Stridsman, Anne Lindberg, Eva Rönmark, Helena Backman ERJ Open Res, 8 (4) 00110-2022; 10.1183/23120541.00110-2022
Infant lung function: criteria for selecting tidal flow–volume loops Karen Eline Stensby Bains, Hrefna Katrín Gudmundsdóttir, Martin Färdig, Erik Amnö, Christine M. Jonassen, Björn Nordlund, Eva Maria Rehbinder, Håvard O. Skjerven, Corina Silvia Rueegg, Riyas Vettukattil, Karin C. Lødrup Carlsen ERJ Open Res, 8 (4) 00165-2022; 10.1183/23120541.00165-2022
Corticosteroid-induced remission and mycophenolate maintenance therapy in granulomatous lymphocytic interstitial lung disease: long-term, longitudinal change in lung function in a single-centre cohort Heba M. Bintalib, David M. Lowe, Gaia Mancuso, Georgia Gkrepi, Suranjith L. Seneviratne, Siobhan O. Burns, John R. Hurst ERJ Open Res, 8 (4) 00024-2022; 10.1183/23120541.00024-2022
Functional clinical impairments and frailty in interstitial lung disease patients Pierre-François Tremblay Labrecque, Geneviève Dion, Didier Saey ERJ Open Res, 8 (4) 00144-2022; 10.1183/23120541.00144-2022
Phase I studies of BI 1015550, a preferential phosphodiesterase 4B inhibitor, in healthy males and patients with idiopathic pulmonary fibrosis Toby M. Maher, Christina Schlecker, Doreen Luedtke, Sebastian Bossert, Donald F. Zoz, Armin Schultz ERJ Open Res, 8 (4) 00240-2022; 10.1183/23120541.00240-2022
Neighbourhood disadvantage impacts on pulmonary function in patients with sarcoidosis Gillian C. Goobie, Christopher J. Ryerson, Kerri A. Johannson, Spencer Keil, Erin Schikowski, Nasreen Khalil, Veronica Marcoux, Deborah Assayag, Hélène Manganas, Jolene H. Fisher, Martin R.J. Kolb, Xiaoping Chen, Kevin F. Gibson, Daniel J. Kass, Yingze Zhang, Kathleen O. Lindell, S. Mehdi Nouraie ERJ Open Res, 8 (4) 00357-2022; 10.1183/23120541.00357-2022
Matrix metalloproteinase-7 is increased in lung bases but not apices in idiopathic pulmonary fibrosis Jade Jaffar, Mae Wong, Gregory A. Fishbein, Monther Alhamdoosh, Laura McMillan, Cristina Gamell-Fulla, Milica Ng, Nick Wilson, Karen Symons, Ian Glaspole, Glen Westall ERJ Open Res, 8 (4) 00191-2022; 10.1183/23120541.00191-2022
Analysis of real-world data and a mouse model indicates that pirfenidone causes pellagra Koji Kuronuma, Natsumi Susai, Tomohiro Kuroita, Hiroki Yamamoto, Takeshi Yoshioka, Shuji Kaneko, Hirofumi Chiba ERJ Open Res, 8 (4) 00245-2022; 10.1183/23120541.00245-2022
Focused lung ultrasound to predict respiratory failure in patients with symptoms of COVID-19: a multicentre prospective cohort study Søren Helbo Skaarup, Rasmus Aagaard, Stig Holm Ovesen, Jesper Weile, Hans Kirkegaard, Caroline Espersen, Mats Christian Højbjerg Lassen, Kristoffer Grundtvig Skaarup, Stefan Posth, Christian B. Laursen, Ask Bock, Michael Dan Arvig, Tor Biering-Sørensen ERJ Open Res, 8 (4) 00128-2022; 10.1183/23120541.00128-2022
Symptoms persisting after hospitalisation for COVID-19: 12 months interim results of the CO-FLOW study L. Martine Bek, Julia C. Berentschot, Majanka H. Heijenbrok-Kal, Susanne Huijts, Michel E. van Genderen, J. Hans Vlake, Jasper van Bommel, Joachim G.J.V. Aerts, Gerard M. Ribbers, Rita J.G. van den Berg-Emons, Merel E. Hellemons ERJ Open Res, 8 (4) 00355-2022; 10.1183/23120541.00355-2022
Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance Antoine Beurnier, Youri Yordanov, Agnès Dechartres, Aurélien Dinh, Erwan Debuc, François-Xavier Lescure, Patrick Jourdain, Luc Jaulmes, Marc Humbert ERJ Open Res, 8 (4) 00012-2022; 10.1183/23120541.00012-2022
Telemedicine home CPAP titration and follow-up in the COVID-19 scenario Jaume Bordas-Martinez, Neus Salord, Eva Fontanilles, Eliseo Prado, María Calvo, João Carmezim, Salud Santos, Carmen Monasterio ERJ Open Res, 8 (4) 00084-2022; 10.1183/23120541.00084-2022
A novel infrasound and audible machine-learning approach to the diagnosis of COVID-19 Guy Dori, Noa Bachner-Hinenzon, Nour Kasim, Haitem Zaidani, Sivan Haia Perl, Shlomo Maayan, Amin Shneifi, Yousef Kian, Tuvia Tiosano, Doron Adler, Yochai Adir ERJ Open Res, 8 (4) 00152-2022; 10.1183/23120541.00152-2022
Prevalence and genetic basis of first-line drug resistance of Mycobacterium tuberculosis in Ca Mau, Vietnam Jack Callum, Phuong T.B. Nguyen, Elena Martinez, Van-Anh T. Nguyen, Frances Garden, Nhung V. Nguyen, Thu-Anh Nguyen, Hoa B. Nguyen, Son V. Nguyen, Khanh B. Luu, Jennifer Ho, Nguyen N. Linh, Warwick J. Britton, Vitali Sintchenko, Greg J. Fox, Guy B. Marks ERJ Open Res, 8 (4) 00122-2022; 10.1183/23120541.00122-2022
Obstructive sleep apnoea-related respiratory events and desaturation severity are associated with the cardiac response Salla Hietakoste, Tuomas Karhu, Saara Sillanmäki, Raquel Bailón, Thomas Penzel, Juha Töyräs, Timo Leppänen, Sami Myllymaa, Samu Kainulainen ERJ Open Res, 8 (4) 00121-2022; 10.1183/23120541.00121-2022
Investigation of the frequency of obstructive sleep apnoea syndrome in patients with subclinical hypothyroidism Aysegul Gencer, Ersan Atahan, Pinar Kadioglu, Birsen Mutlu ERJ Open Res, 8 (4) 00186-2022; 10.1183/23120541.00186-2022
Validation of the cough phenotype TBQ among elderly Finnish subjects Heikki O. Koskela, Johanna T. Kaulamo, Tuomas A. Selander, Anne M. Lätti ERJ Open Res, 8 (4) 00284-2022; 10.1183/23120541.00284-2022
Family case studies: absence of Pseudomonas aeruginosa transmission in bronchiectasis Ruth Sobala, Kristian Brooks, John Davison, Joanna Lumb, Anthony De Soyza ERJ Open Res, 8 (4) 00280-2022; 10.1183/23120541.00280-2022
“A double-blind randomised controlled trial of protein supplementation to enhance exercise capacity in COPD during pulmonary rehabilitation: a pilot study”. Abdulelah M. Aldhahir, Yousef S. Aldabayan, Jaber S. Alqahtani, Heidi A. Ridsdale, Colette Smith, John R. Hurst and Swapna Mandal. ERJ Open Res 2021; 7: 00077-2021 ERJ Open Res, 8 (4) 50077-2021; 10.1183/23120541.50077-2021
Infant lung function and maternal physical activity in the first half of pregnancy Hrefna Katrín Gudmundsdóttir, Oda C.L. Carlsen, Karen Eline Stensby Bains, Martin Färdig, Guttorm Haugen, Christine M. Jonassen, Marissa LeBlanc, Björn Nordlund, Eva Maria Rehbinder, Håvard O. Skjerven, Anne Cathrine Staff, Riyas Vettukattil, Karin C. Lødrup Carlsen ERJ Open Res, 8 (4) 00172-2022; 10.1183/23120541.00172-2022
Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort Ashraf Yassen, Katrin Coboeken, Sébastien Bailly, Rolf Burghaus, Jitka Buskova, Zoran Dogas, Marta Drummond, Haralampos Gouveris, Pavol Joppa, Joerg Lippert, Carolina Lombardi, Stefan Mihaicuta, Jean Louis Pépin, Ding Zou, Jan Hedner, Ludger Grote ERJ Open Res, 8 (4) 00132-2022; 10.1183/23120541.00132-2022
Dual CFTR modulator therapy efficacy in the real world: lessons for the future Anna-Maria Dittrich, Sandra Y. Chuang ERJ Open Res, 8 (4) 00464-2022; 10.1183/23120541.00464-2022
Complex pathways leading to future paediatric asthma exacerbations Amrita Dosanjh ERJ Open Res, 8 (4) 00322-2022; 10.1183/23120541.00322-2022
Multidrug-resistant tuberculosis: diagnosis, checklists, adverse events, advice and outcomes Graham H. Bothamley ERJ Open Res, 8 (4) 00512-2022; 10.1183/23120541.00512-2022
Airway disease: a confusion inside an enigma Alyn H. Morice ERJ Open Res, 8 (4) 00519-2022; 10.1183/23120541.00519-2022
Assessment of factors and interventions towards therapeutic adherence among persons with non-cystic fibrosis bronchiectasis Christina S. Thornton, Ranjani Somayaji, Rachel K. Lim ERJ Open Res, 8 (4) 00340-2022; 10.1183/23120541.00340-2022
Pulmonary hypertension in interstitial lung disease: an area of unmet clinical need Sebastiaan Dhont, Bert Zwaenepoel, Els Vandecasteele, Guy Brusselle, Michel De Pauw ERJ Open Res, 8 (4) 00272-2022; 10.1183/23120541.00272-2022
COVID-19 therapies for inpatients: a review and quality assessment of clinical guidelines David A. Wohl, Aprille A. Espinueva, Lauren Dau, Chen-Yu Wang, Alexandra Lachmann, Rujuta A. Bam, Aaditya Rawal, Kerris Chappell-Smith, Juergen K. Rockstroh ERJ Open Res, 8 (4) 00236-2022; 10.1183/23120541.00236-2022
Clinical assessment of balance and functional impairments in people with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis Rodrigo Núñez-Cortés, Paloma Padilla-Acevedo, Franchesca Vergara-Peña, Sara Mollà-Casanova, Claudia Espinoza-Bravo, Rodrigo Torres-Castro, Carlos Cruz-Montecinos ERJ Open Res, 8 (4) 00164-2022; 10.1183/23120541.00164-2022
AROMA: real-world global registry of dupilumab for chronic rhinosinusitis with nasal polyps Shahid Siddiqui, Claus Bachert, Adam M. Chaker, Joseph K. Han, Peter W. Hellings, Anju T. Peters, Enrico Heffler, Siddhesh Kamat, Haixin Zhang, Scott Nash, Asif H. Khan, Lucia De Prado Gomez, Juby A. Jacob-Nara, Paul J. Rowe, Yamo Deniz ERJ Open Res, 8 (4) 00085-2022; 10.1183/23120541.00085-2022
Past asthma exacerbation in children predicting future exacerbation: a systematic review Rachel Lowden, Steve Turner ERJ Open Res, 8 (4) 00174-2022; 10.1183/23120541.00174-2022
Early-life risk factors for development of asthma from 8 to 28 years of age: a prospective cohort study Linnéa Hedman, Linnéa Almqvist, Anders Bjerg, Martin Andersson, Helena Backman, Matthew S. Perzanowski, Eva Rönmark ERJ Open Res, 8 (4) 00074-2022; 10.1183/23120541.00074-2022
Exercise rehabilitation in COPD and heart failure: comparison of two national audits Amy V. Jones, Rachael A. Evans, Alexander S. Harrison, Lauren B. Sherar, Michael C. Steiner, Patrick Doherty, Sally J. Singh ERJ Open Res, 8 (4) 00131-2022; 10.1183/23120541.00131-2022
Improving the wellbeing of caregivers of patients with COPD using a home-based pulmonary rehabilitation programme Jean-Marie Grosbois, Sarah Gephine, Maeva Kyheng, Olivier Le Rouzic, Cécile Chenivesse ERJ Open Res, 8 (4) 00255-2022; 10.1183/23120541.00255-2022
Long-term follow-up after bronchoscopic lung volume reduction valve treatment for emphysema Jorine E. Hartman, Karin Klooster, T. David Koster, Nick H.T. ten Hacken, Marlies van Dijk, Dirk-Jan Slebos ERJ Open Res, 8 (4) 00235-2022; 10.1183/23120541.00235-2022
Relevance of comorbidities on initial combination therapy in pulmonary arterial hypertension Roberto Badagliacca, Michele D'Alto, Stefano Ghio, Paola Argiento, Natale Daniele Brunetti, Gavino Casu, Nadia Cedrone, Marco Confalonieri, Marco Corda, Michele Correale, Carlo D'Agostino, Lucrezia De Michele, Serena Di Marino, Domenico Filomena, Giuseppe Galgano, Alessandra Greco, Carlo Lombardi, Giovanna Manzi, Valentina Mercurio, Massimiliano Mulè, Giuseppe Paciocco, Silvia Papa, Emanuele Romeo, Laura Scelsi, Davide Stolfo, Patrizio Vitulo, Carmine Dario Vizza ERJ Open Res, 8 (4) 00298-2022; 10.1183/23120541.00298-2022
1-year mortality in lung cancer in France according to key timepoints of care pathways Axelle Rivière, Anne Isabelle Lecuyer, Emeline Laurent, Carole Lefebvre, Thierry Lecomte, Elodie Olivier, Delphine Carmier, Laurent Plantier, Leslie Grammatico-Guillon ERJ Open Res, 8 (4) 00157-2022; 10.1183/23120541.00157-2022
Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century Lucia Cestelli, Ane Johannessen, Knut Stavem, Amund Gulsvik, Rune Nielsen ERJ Open Res, 8 (4) 00302-2022; 10.1183/23120541.00302-2022
Effect of nintedanib on acute exacerbations of fibrosing interstitial lung diseases: a national database study in Japan Hirokazu Urushiyama, Taisuke Jo, Wakae Hasegawa, Akira Yokoyama, Takahiro Ando, Yukiyo Sakamoto, Ryosuke Kumazawa, Kazuaki Uda, Nobuaki Michihata, Nobuyasu Awano, Matsui Hiroki, Kiyohide Fushimi, Hideo Yasunaga, Takahide Nagase ERJ Open Res, 8 (4) 00209-2022; 10.1183/23120541.00209-2022
Interferon-? release assay screening in biologics: safe and reliable, but not perfect John Cafferkey, Yorissa Padayachee, Sophia Kostich, Kartik Kumar, Paul Jewell, Mikin Patel, Aneeka Chavda, Alison Cox, Mirae Park, Georgina Russell, Meg Coleman, Laura Martin, Onn Min Kon ERJ Open Res, 8 (4) 00193-2022; 10.1183/23120541.00193-2022
Multidrug-resistant tuberculosis in Finland: treatment outcome and the role of whole-genome sequencing Virve Korhonen, Pia Kivelä, Marjo Haanperä, Hanna Soini, Tuula Vasankari ERJ Open Res, 8 (4) 00214-2022; 10.1183/23120541.00214-2022
Nontuberculous mycobacterial infections during cancer therapy with immune checkpoint inhibitors: a systematic review Andrea Lombardi, Andrea Gramegna, Margherita Ori, Cecilia Azzarà, Francesco Blasi, Andrea Gori ERJ Open Res, 8 (4) 00364-2022; 10.1183/23120541.00364-2022
Nontuberculous mycobacteria infection and pulmonary disease in bronchiectasis Kseniia Suska, Francesco Amati, Giovanni Sotgiu, Andrea Gramegna, Marco Mantero, Margherita Ori, Maurizio Ferrarese, Luigi Ruffo Codecasa, Anna Stainer, Francesco Blasi, Stefano Aliberti ERJ Open Res, 8 (4) 00060-2022; 10.1183/23120541.00060-2022
The demographics, clinical characteristics and quality of life of patients with chronic cough from the Isala Cough Clinic in the Netherlands Jan Willem K. van den Berg, Carl A. Baxter, Mireille A. Edens, Kornelis W. Patberg, Hester van der Velden, Arjan Weijerse, Stina Salomonsson ERJ Open Res, 8 (4) 00232-2022; 10.1183/23120541.00232-2022
The long-term effects of insulin use in incident cystic fibrosis-related diabetes: a target trial emulated using longitudinal national registry data Emily Granger, Ruth H. Keogh, Freddy Frost ERJ Open Res, 8 (4) 00170-2022; 10.1183/23120541.00170-2022
Long-term effectiveness of dual CFTR modulator treatment of cystic fibrosis Danya Muilwijk, Domenique D. Zomer-van Ommen, Vincent A.M. Gulmans, Marinus J.C. Eijkemans, Cornelis K. van der Ent ERJ Open Res, 8 (4) 00204-2022; 10.1183/23120541.00204-2022
Diagnostic agreement among experts assessing adults presenting with possible cystic fibrosis: need for improvement and implications for patient care Alessandro N. Franciosi, April Tanzler, Jodi Goodwin, Pearce G. Wilcox, George M. Solomon, Albert Faro, Noel G. McElvaney, Damian G. Downey, Bradley S. Quon ERJ Open Res, 8 (4) 00227-2022; 10.1183/23120541.00227-2022
Nasal epithelial cell culture fluorescence recovery after photobleaching predicts cystic fibrosis therapeutic response Timothy E. Corcoran, Carol A. Bertrand, Michael M. Myerburg, Daniel J. Weiner, Sheila A. Frizzell, Anna Li, Brittani Agostini, Robert S. Parker, Monica E. Shapiro, Ashok Muthukrishnan, Nicholas D. Hages, Brian P. Mulhern, Joseph M. Pilewski ERJ Open Res, 8 (4) 00382-2022; 10.1183/23120541.00382-2022
Respiratory symptoms and their determinants in the general Spanish population: changes over 20 years Marc Miravitlles, Juan José Soler-Cataluña, Joan B. Soriano, Francisco García-Río, Pilar de Lucas, Inmaculada Alfageme, Ciro Casanova, José Miguel Rodríguez González-Moro, Guadalupe Sánchez, Julio Ancochea, Borja G. Cosío ERJ Open Res, 8 (4) 00067-2022; 10.1183/23120541.00067-2022
Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings Ann Hutchinson, Victoria Allgar, Judith Cohen, David C. Currow, Susan Griffin, Simon Hart, Kelly Hird, Andrew Hodge, Suzanne Mason, Matthew Northgraves, Joanne Reeve, Flavia Swan, Miriam J. Johnson ERJ Open Res, 8 (4) 00257-2022; 10.1183/23120541.00257-2022
Sputum neutrophil counts in healthy subjects: relationship with age Augusta Beech, Dave Singh ERJ Open Res, 8 (4) 00246-2022; 10.1183/23120541.00246-2022
Pathological characteristics of mediastinal masses in Sri Lanka 2017–2021: a retrospective observational study Yasith Mathangasinghe, Saman Pradeep, Udeshika Perera, Ramani Punchihewa ERJ Open Res, 8 (4) 00256-2022; 10.1183/23120541.00256-2022
Persistent isolated impairment of gas transfer following COVID-19 pneumonitis relates to perfusion defects on dual-energy computed tomography Laura C. Price, Benjamin Garfield, Chloe Bloom, Nidhish Jeyin, Daniel Nissan, James H. Hull, Brijesh Patel, Gisli Jenkins, Simon Padley, William Man, Suveer Singh, Carole A. Ridge ERJ Open Res, 8 (4) 00224-2022; 10.1183/23120541.00224-2022
Is it feasible to perform a continuous laryngoscopy exercise test with a cold air inhalate? A case report Haakon Kvidaland, Sandra Stadheim, Signe Bø, Hege Clemm, Ola D. Røksund, Maria Vollsæter, Jon Hardie ERJ Open Res, 8 (4) 00222-2022; 10.1183/23120541.00222-2022
Pharmacotherapy for lung cancer with comorbid interstitial pneumonia: limited evidence requires appropriate evaluation Yuriko Ishida, Satoshi Ikeda, Akimasa Sekine, Tomohisa Baba, Takashi Ogura ERJ Open Res, 8 (4) 00337-2022; 10.1183/23120541.00337-2022
Reply to: Pharmacotherapy for lung cancer with comorbid interstitial pneumonia: limited evidence requires appropriate evaluation Manuela Funke-Chambour, Namrata Kewalramani, Carlos Machahua, Venerino Poletti, Athol U. Wells, Jacques Cadranel ERJ Open Res, 8 (4) 00469-2022; 10.1183/23120541.00469-2022
Development and validation of an interstitial lung disease exposure questionnaire for sub-Saharan Africa Peter Jackson, Roma Padalkar, Winceslaus Katagira, Kevin Mortimer, Natalie A. Rykiel, Nicole M. Robertson, Suzanne L. Pollard, Patricia Alupo, William Checkley, Bruce Kirenga, Trishul Siddharthan ERJ Open Res, 8 (4) 00205-2022; 10.1183/23120541.00205-2022
Developing a self-management package for pulmonary fibrosis: an international Delphi study Joanna Y.T. Lee, Gabriella Tikellis, Yet H. Khor, Anne E. Holland ERJ Open Res, 8 (4) 00349-2022; 10.1183/23120541.00349-2022
The trajectory of COVID-19 cardiopulmonary disease: insights from an autopsy study of community-based, pre-hospital deaths Luke Milross, Joaquim Majo, Julian Pulle, Sam Hoggard, Nigel Cooper, Bethany Hunter, Christopher J.A. Duncan, Andrew Filby, Andrew J. Fisher ERJ Open Res, 8 (4) 00303-2022; 10.1183/23120541.00303-2022
Feasibility of transbronchial lung cryobiopsy in patients with veno-venous extracorporeal membrane oxygenation support Shiyao Wang, Guowu Zhou, Yingying Feng, Yi Zhang, Ye Tian, Sichao Gu, Xiaojing Wu, Meiyuan Li, Yiming Feng, Dan Wang, Ying Li, Zheng Tian, Ling Zhao, Min Li, Wenhui Chen, Xu Huang, Qingyuan Zhan ERJ Open Res, 8 (4) 00383-2022; 10.1183/23120541.00383-2022
Negative association between fatigue and signs of sleep apnoea in patients after COVID-19 Markus C. Hayden, Gabriele Schwarzl, Matthias Limbach, Sorin Mitrea, Michael Schuler, Dennis Nowak, Konrad Schultz ERJ Open Res, 8 (4) 00289-2022; 10.1183/23120541.00289-2022
Targeted lung denervation modulates the mucosal epithelial transcriptome in COPD Karthi Srikanthan, Loes Kistemaker, Dirk-Jan Slebos, Wolfgang Gesierich, Kaid Darwiche, Peter Bonta, Gaetan Deslee, Pallav Shah, Reinoud Gosens ERJ Open Res, 8 (4) 00146-2022; 10.1183/23120541.00146-2022
Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19 Florian Tran, Danielle M.M. Harris, Alena Scharmacher, Hanna Graßhoff, Kristina Sterner, Susanne Schinke, Nadja Käding, Jens Y. Humrich, Otávio Cabral-Marques, Joana P. Bernardes, Neha Mishra, Thomas Bahmer, Jeanette Franzenburg, Bimba F. Hoyer, Andreas Glück, Martina Guggeis, Alexander Ossysek, Andre Küller, Derk Frank, Christoph Lange, Jan Rupp, Jan Heyckendorf, Karoline I. Gaede, Howard Amital, Philip Rosenstiel, Yehuda Shoenfeld, Gilad Halpert, Avi Z. Rosenberg, Kai Schulze-Forster, Harald Heidecke, Gabriela Riemekasten, Stefan Schreiber ERJ Open Res, 8 (4) 00379-2022; 10.1183/23120541.00379-2022
Nanopore-based metagenomic sequencing: a diagnostic tool in respiratory tract infection Robert Chapman, Alberto D'Angelo, Stefan Bagby ERJ Open Res, 8 (4) 00461-2022; 10.1183/23120541.00461-2022