Combining an epithelial repair factor and anti-fibrotic with a corticosteroid offers optimal treatment for the pathogenesis of allergic airways disease
Krupesh Patel (Glen Waverley, Australia), Krupesh Patel, Chrishan Samuel, Simon Royce
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Neutrophils in bronchial mucosa, sputum and blood after administration of the CXCR2-antagonist AZD5069 - An explorative study in neutrophilic asthma
Henrik Watz (Grosshansdorf, Germany), Henrik Watz, Anne Kirsten, Frauke Pedersen, Torsten Goldmann, Florian Stellmacher, Mohib Uddin, Bengt Larsson, Gerhard Böttcher, Anna Malmgren, Marteen Kraan, Klaus Rabe
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Roflumilast but not dexamethasone or fluticasone reduces neutrophilic airway inflammation and hyperreactivity in a murine influenza-induced asthma exacerbation model
Cornelia Tilp (Biberach an der Riss, Germany), Cornelia Tilp, Hannes Bucher, Eva Wex, Klaus Erb
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A fixed combination of thyme and primula dry extracts normalizes goblet cell hyperplasia and MUC5AC formation in vivo and in vitro
Jan Seibel (Neumarkt i.d.OPf., Germany), Jan Seibel, Aldo Ammendola, Martin Lehner
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Effects of phosphoinositide-3-kinase inhibitors on steroid-insensitive airway inflammation in poly(I:C) and allergen challenged mice
Genki Kimura (Funabashi, Japan), Genki Kimura, Yuki Nishimoto, Keitaro Ueda, Takahiro Nakaoki, Takashi Masuko, Peter J. Barnes, Kazuhiro Ito, Yasuo Kizawa
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Enrichment of the Janus kinase (JAK) activation signature in severe asthma sputum: Correlation with IL-13 expression
Stelios Pavlidis (London, United Kingdom), Stelios Pavlidis, Ian Adcock, Fan Chung, Anthony Rowe, Christos Rossios, Ioannis Pandis, Ratko Djukanovich, Peter Sterk, Yike Guo, Coen Wiegman
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Relationship between mitochondrial function and cellular ageing depends upon compartment analysed
Stelios Pavlidis (London, United Kingdom), Stelios Pavlidis, Fan Chung, Anthony Rowe, Ioannis Pandis, Ratko Djukanovic, Peter Sterk, Yi-ke Guo, Ian Adcock
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Adrenal insufficiency in asthma patients – Who is at risk?
Sam Roberts (Leeds, United Kingdom), Sam Roberts, Tim Sutherland, Jane Slough, Rhodri King, Robert Murray, Ian Clifton
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TNFAIP3 (A20) expression is elevated in the sputum of severe asthmatics
Stelios Pavlidis (London, United Kingdom), Stelios Pavlidis, Fan Chung, Anthony Rowe, Ioannis Pandis, Ratko Djukanovic, Peter Sterk, Yike Guo, Ian Adcock
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Omalizumab, airway obstruction and remodeling
Michela Maria Bellocchia (Turin, Italy), Michela Maria Bellocchia, Renza Ambrosanio, Filippo Patrucco, Giulia Verri, Lorena Mercante, Monica Boita, Giuseppe Tabbbia, Alessio Mattei, Paolo Solidoro, Caterina Bucca
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Modulation of inflammation by benralizumab in eosinophilic airway disease
Paul Newbold (Gaithersburg, United States of America), Paul Newbold, Hao Liu, Tuyet-Hang Pham, Gautam Damera, Sriram Sridhar
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Budesonide/formoterol maintenance and reliever therapy in adolescent patients with asthma
Hans Bisgaard (Copenhagen, Denmark), Hans Bisgaard, Dan Lythgoe, Carin Jorup
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Tiotropium reduces oral prednisone requirements while improving respiratory function in patients with severe persistent asthma
Bashir Omarjee (Saint-Denis/La Réunion, Reunion), Bashir Omarjee
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RPL554, an inhaled PDE3/4 inhibitor, causes comparable bronchodilation to high dose nebulised salbutamol in asthmatics with fewer systemic effects
Leif Bjermer (Lund, Sweden), Leif Bjermer, Johnston Stewart, Katharine Abbott-Banner, Kenneth Newman
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Bronchial thermoplasty resulted in an increase of CD4+CD25+ regulatory T cells in severe asthma patients
Mateja Marc Malovrh (Kranj, Slovenia), Mateja Marc Malovrh, Aleš Rozman, Sabina Škrgat, Mira Šilar, Julij Šelb, Peter Korošec
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Dysphonia in asthmatic women using inhaled corticosteroids: It is not only a laryngeal inflammation
Frédéric de Blay (Strasbourg, France), Frédéric de Blay, Christina Delmas, Elisabeth Peri, Michel Velten, Julie Petit-Thomas, Helene Kuntz, Philippe Schultz
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