Neutrophils in bronchial mucosa, sputum and blood after administration of the CXCR2-antagonist AZD5069 - An explorative study in neutrophilic asthma

Henrik Watz (Grosshansdorf, Germany), Henrik Watz, Anne Kirsten, Frauke Pedersen, Torsten Goldmann, Florian Stellmacher, Mohib Uddin, Bengt Larsson, Gerhard Böttcher, Anna Malmgren, Marteen Kraan, Klaus Rabe

Source: International Congress 2016 – Novel mechanisms and treatment modalities in asthma
Session: Novel mechanisms and treatment modalities in asthma
Session type: Poster Discussion
Number: 4892
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Henrik Watz (Grosshansdorf, Germany), Henrik Watz, Anne Kirsten, Frauke Pedersen, Torsten Goldmann, Florian Stellmacher, Mohib Uddin, Bengt Larsson, Gerhard Böttcher, Anna Malmgren, Marteen Kraan, Klaus Rabe. Neutrophils in bronchial mucosa, sputum and blood after administration of the CXCR2-antagonist AZD5069 - An explorative study in neutrophilic asthma. Eur Respir J 2016; 48: Suppl. 60, 4892

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Monitoring sputum eosinophils in mucosal inflammation and remodelling: a pilot study
Source: Eur Respir J 2010; 35: 48-53
Year: 2010



Decrease in a quantity of the eosinophils in bioptates of the mucosa of bronchial tree of patients with bronchial asthma associated with stressful life events
Source: Annual Congress 2013 –The vulnerable patient and ageing cells
Year: 2013

The airway microbiota is significantly altered in asthma patients with airway hyperresponsiveness to mannitol
Source: International Congress 2015 – Exploring mechanisms in obstructive airway diseases
Year: 2015

Peripheral blood eosinophilia predicts lower airway eosinophilia in asthma and COPD
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015


LATE-BREAKING ABSTRACT: Sputum transcriptome analysis yields eosinophilic and non-eosinophilic inflammatory mechanisms in UBIOPRED asthma cohort
Source: International Congress 2015 – Translational research in respiratory care: new findings
Year: 2015

Asthma
Source: Respipedia Article
Year: 2018

Asthma control and sputum eosinophils: A longitudinal study in daily practice
Source: International Congress 2015 – Exploring mechanisms in obstructive airway diseases
Year: 2015


The effect of bronchial thermoplasty on nerve C-fibers and inflammatory cells in patients with severe asthma
Source: International Congress 2015 – Bronchoscopic treatment of emphysema and asthma: what is new?
Year: 2015


Cytological and mRNAs peripheral blood markers of aspirin intolerance in asthmatics
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015

Periostin in lower airway samples and serum, a novel asthma marker?
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015


LATE-BREAKING ABSTRACT: Bronchial microbiome in severe persistent oral corticosteroid-dependent asthma
Source: International Congress 2015 – Respiratory infections: from basic science to clinical issues
Year: 2015

Eosinophilic inflammation in sputum of poorly controlled asthmatics
Source: Eur Respir J 2002; 20: 1370-1377
Year: 2002



Airway inflammation and hyperresponsiveness study in skier children determined by induced sputum and mannitol test
Source: International Congress 2015 – Paediatric asthma and allergy: lung function and biomarkers
Year: 2015


Bronchoscopic evaluation of the lower airways in patients with persistent severe asthma
Source: International Congress 2015 – Sedation and educational issues in bronchoscopy: basic bronchoscopic techniques
Year: 2015


Myeloperoxidase of bronchial leucocytes as a biomarker of osmotic bronchial hyperresponsiveness in asthmatics
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015


Disconnect between sputum neutrophils and other measures of airway inflammation in asthma
Source: Eur Respir J 2014; 43: 627-629
Year: 2013


Lung microbiome is associated with asthma severity in fungal associated asthma
Source: International Congress 2015 – Phenotyping asthma with biomarkers
Year: 2015


Airway basophils are increased and correlated with eosinophilic inflammtaion in asthma and COPD
Source: International Congress 2015 – Exploring mechanisms in obstructive airway diseases
Year: 2015

Sputum microbiota in Chinese adults with eosinophilic versus non-eosinophilic asthma
Source: International Congress 2015 – Clincal aspects of asthma: monitoring and mechanisms
Year: 2015


Monitoring of sputum eosinophils in long-term treatment of bronchial asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 111s
Year: 2002