G. Caramori (Ferrara, Italy), I.M. Adcock (London, United Kingdom)
A novel inhaled PI3Kδ inhibitor, LAS194223 reduces allergen-induced airway inflammation in rat
M. Calbet, M. Lehner, E. Calama, A. Domenech, J. Cabedo, M. Dominguez, M. Erra, J. De Alba, N. Prats, M. Miralpeix (Sant Feliu del Llobregat, Spain)
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Safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single (SD) and repeat (RD) inhaled doses of a novel phosphoinositide 3-kinase δ inhibitor (PI3Kδ), GSK2269557, administered to healthy smokers
R. Wilson, A. Cahn, M. Montembault, J. Green, N. Musani, M. Begg, A. Deans, J. Gilbert, S. Ahmed, A. Kielkowska, J. Clark, M. Boyce, E. M. Hessel, P. Ventresca (Stevenage, London, Cambridge, United Kingdom)
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New inhaled JAK inhibitor LAS194046 inhibits allergen-induced airway inflammation in Brown Norway rats
I. Ramis, E. Calama, A. Domènech, C. Carreño, E. Calaf, M. Cordoba, J. Alberti, J. De Alba, J. Bach, N. Prats, M. Miralpeix (Sant Feliu de Llobregat, Spain)
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Inhibition of JAK/STAT pathway in airway epithelium as a potential targeted therapy of asthma
A. Bujak, P. Nejman-Gryz, P. Gunerka, M. Lamparska-Przybysz, M. Wieczorek, R. Chazan, A. Stanczak (Kielpin/Lomianki, Warsaw, Lodz, Poland)
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Inhibitor effect of Janus kinase II in bleomycin-induced pulmonary fibrosis model
G. Hernandez, L. Diaz, A. Serrano, J. Milara, J. Cortijo (Valencia, Spain)
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LSC 2014 abstract - Deciphering of the mechanism of the anti-asthmatic action of the CXCL12 neutraligand, chalcone 4
F. Daubeuf, D. Bonnet, V. Beckaert, A. Ouadi, P. Marchand, D. Brasse, P. Gizzi, M. Hibert, J. L. Galzi, N. Frossard (Illkirch, Strasbourg, France)
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The novel elastase inhibitor BAY 85-8501 provides a new approach in the treatment of pulmonary diseases
J. Nagelschmitz, D. Kaufel, S. Stephan, F. von Nussbaum, V. Li, M. Delbeck, K. Lustig, T. Bandel, H. Watz (Wuppertal, Grosshansdorf, Germany)
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The anti-proliferative effect of hydrogen sulfide upon human airway smooth muscle in COPD
M. Perry, A. Tu, G. Sehra, I. Adcock, F. Chung (London, United Kingdom)
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