Source: International Congress 2014 – New drugs for asthma, COPD and pulmonary fibrosis
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
A. Bujak, P. Nejman-Gryz, P. Gunerka, M. Lamparska-Przybysz, M. Wieczorek, R. Chazan, A. Stanczak (Kielpin/Lomianki, Warsaw, Lodz, Poland). Inhibition of JAK/STAT pathway in airway epithelium as a potential targeted therapy of asthma. Eur Respir J 2014; 44: Suppl. 58, 3413

Member's Comments

No comment yet.

Related content which might interest you: Blockade of TSLP pathway alters asthma biomarkers Source: International Congress 2014 – Clinical trials of drugs for respiratory diseases Year: 2014 A novel inhaled PI3Kδ inhibitor, LAS194223 reduces allergen-induced airway inflammation in rat Source: International Congress 2014 – New drugs for asthma, COPD and pulmonary fibrosis Year: 2014 Therapeutic potential of CPL-407-105 – Novel potent JAK/STAT pathway inhibitor for the treatment of asthma Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs Year: 2014 Lung specific induction of Wnt-1 has a prophylactic and therapeutic effect on the development of an allergic airway disease Source: Annual Congress 2013 –Murine models of lung immunology Year: 2013 New inhaled JAK inhibitor LAS194046 inhibits allergen-induced airway inflammation in Brown Norway rats Source: International Congress 2014 – New drugs for asthma, COPD and pulmonary fibrosis Year: 2014 Expression of CysLT2 receptors in asthmatic lung, and the roles in bronchoconstriction Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases Year: 2014 In vitro characterization of a novel inhaled PI3Kd inhibitor LAS194223 Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs Year: 2014 Enhanced inflammatory gene expression in bronchial epithelial cells from asthmatic patients: Attenuation by a Brd4 mimic Source: International Congress 2014 – Novel targets and drugs for asthma and COPD Year: 2014 In vitro profile of the new inhaled pan-JAK inhibitor LAS194046 Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs Year: 2014 Effectively targeting small airways using controlled inhalation for peripheral corticosteroid deposition Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases Year: 2014 Activation of the β-catenin pathway by Wnt-1 treatment suppress inflammation in the mouse model of allergic airway disease Source: International Congress 2015 – Advances in asthma and allergy in animal models Year: 2015 Association between airway inflammation, airway remodelling and physiological changes in asthma Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases Year: 2014 The anti-inflammatory effects of sulforaphane are not mediated by the Nrf2 pathway Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases Year: 2014 LATE-BREAKING ABSTRACT: Effects of a dual CysLT1/2 antagonist, ONO-6950, on allergen-induced airway responses in subjects with mild allergic asthma. Source: International Congress 2014 – Latest insights in airway diseases Year: 2014 Characteristics of the adult corticosteroid-dependent severe asthma in UBIOPRED consortium Source: International Congress 2014 – Novel targets and drugs for asthma and COPD Year: 2014 Species comparison of interleukin-13 induced airway hyperreactivity as model for allergic asthma Source: International Congress 2014 – Animal models in respiratory drug development Year: 2014 LATE-BREAKING ABSTRACT: Attenuation of allergen-induced asthmatic responses by inhaled GATA-3 specific DNAzyme Source: International Congress 2014 – Latest insights in airway diseases Year: 2014 Clinical effectiveness of anti-IgE therapy in allergic severe asthma Source: International Congress 2014 – Asthma and COPD management Year: 2014 ADEPT-derived, U-BIOPRED validated asthma clinical clusters with Th2 and non-Th2 phenotypes Source: International Congress 2014 – Novel targets and drugs for asthma and COPD Year: 2014 Preventative administration of IL-27 improves airway inflammation of ovalbumin –induced asthma mice model via both STAT1 and GADD45γ/p38MAPK pathways Source: International Congress 2016 – Pharmacological intervention in humans and murine models of asthma Year: 2016