In vitro pharmacological characterization of the potent, lung selective pan-JAK inhibitor TD-8236 Source: International Congress 2019 – Advances in asthma pharmacology Year: 2019
A functional variant of secretory leukocyte protease inhibitor (SLPI) with improved anti-inflammatory activity against pulmonary infection Source: Lung Science Conference 2015 Year: 2015
In vitro and in vivo anti-inflammatory activity of the novel PDE4 inhibitor roflumilastSource: Eur Respir J 2001; 18: Suppl. 33, 35s Year: 2001
LSC Abstract – A functional variant of secretory leukocyte protease inhibitor (SLPI) with improved anti-inflammatory activity against pulmonary infection Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects Year: 2015
The novel phosphodiesterase 4 inhibitor CI-1044 inhibits in vitro LPS-induced TNFα production in whole blood of COPD patients Source: Eur Respir J 2001; 18: Suppl. 33, 34s Year: 2001
AZD9668: Pharmacological characterisation of a novel oral inhibitor of neutrophil elastase (NE) Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
Roflumilast inhibits leukocyte cell interactions in vivo Source: Eur Respir J 2006; 28: Suppl. 50, 224s Year: 2006
The effect of recombinant Il-8 on eosinophil migration in vitro and in vivo Source: Eur Respir J 2002; 20: Suppl. 38, 382s Year: 2002
Pharmacological characterization of CHI25243, a novel potent inhaled inhibitor of neutrophil elastase Source: International Congress 2016 – Therapeutic horizons: novel targets and pharmacological models Year: 2016
An innovative high sensitivity tool for active neutrophil elastase quantification Source: Virtual Congress 2021 – Biomarkers for the management of bronchial obstructive diseases Year: 2021
The selective phosphodiesterase 4 inhibitor, cilomilast, inhibits interleukin-8-induced pulmonary neutrophil accumulation in the rabbit Source: Eur Respir J 2001; 18: Suppl. 33, 35s Year: 2001
Effects of N-acetylcysteine and salbutamol on neutrophil migration and release of interleukin-8 and elastase by neutrophils in vitro Source: Eur Respir J 2004; 24: Suppl. 48, 579s Year: 2004
The phosphodiesterase 4 inhibitor SB 207499 selectively inhibits neutrophil functions Source: Eur Respir J 2001; 18: Suppl. 33, 34s Year: 2001
Neutrophil activity assessed using a novel serological marker of human neutrophil elastase degraded calprotectin is elevated in patients with COPD or IPF Source: Virtual Congress 2021 – Advanced in vitro models for drug discovery Year: 2021
Usefulness of selective neutrophil elastase inhibitor, sivelestat, in ALI patients with SIRS Source: Annual Congress 2012 - How to use technology to provide better critical care Year: 2012
Zaphirlukast inhibits in vitro the respiratory burst of human neutrophils Source: Eur Respir J 2001; 18: Suppl. 33, 79s Year: 2001
Effect of human neutrophil proteases on ex vivo small airway function Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung Year: 2013
²Classical vasodilators² inhibit the recruitment of polymorphonuclear leukocytes in vitro Source: Eur Respir J 2005; 26: Suppl. 49, 352s Year: 2005
Evidence that cathepsin G counteracts the profibrotic effects of neutrophil elastase following lung injury Source: Eur Respir J 2001; 18: Suppl. 33, 181s Year: 2001
Investigating optimal sputum processing methods for active neutrophil elastase quantification Source: International Congress 2017 – Techniques in biomarker selection Year: 2017