Scientific advances in airway pharmacology

E-poster session
Chairs: R. Gosens (Groningen, Netherlands), L. Kistemaker (Groningen, Netherlands)

Late Breaking Abstract - Inhaled corticosteroids in bronchiectasis is associated to increased morbidity, Pseudomonas colonization and mortality – a five-year prospective cohort study K. Håkansson (Hvidovre, Denmark), K. Fjaellegaard (Naestved, Denmark), A. Browatzki (Hilleroed, Denmark), M. Sin (Hvidovre, Denmark), C. Suppli Ulrik (Hvidovre, Denmark)
Late Breaking Abstract - Anti-inflammatory and anti-fibrotic effect of novel, pan-PDE inhibitors in human bronchial epithelial cells K. Wójcik-Pszczola (Kraków, Poland), B. Jakiela (Kraków, Poland), H. Plutecka (Kraków, Poland), A. Jankowska (Kraków, Poland), M. Slusarczyk (Kraków, Poland), G. Chlon-Rzepa (Kraków, Poland), K. Pociecha (Kraków, Poland), A. Swierczek (Kraków, Poland), E. Wyska (Kraków, Poland), P. Koczurkiewicz-Adamczyk (Kraków, Poland), E. Pekala (Kraków, Poland), R. Gosens (Groningen, Netherlands)
Safety, pharmacokinetics and pharmacodynamics of BI 1323495 in healthy males M. Desch (Biberach, Germany), R. Sennewald (Biberach, Germany), A. Eleftheraki (Biberach, Germany), H. Kögler (Ingelheim am Rhein, Germany), C. Diefenbach (Biberach, Germany)
Arrhythmogenic and chronotropic effects of bronchodilator drugs on human cardiomyocytes M. Šcurek (Brno, Czech Republic), M. Pešl (Brno, Czech Republic), J. Pribyl (Brno, Czech Republic), Š. Klimovic (Brno, Czech Republic), T. Urban (Brno, Czech Republic), Š. Jelínková (Brno, Czech Republic), V. Rotrekl (Brno, Czech Republic), K. Brat (Brno, Czech Republic)
Transient receptor potential vanilloid 4 channels mediate resistive breathing-induced acute lung injury. D. Toumpanakis (Athens, Greece), A. Chatzianastasiou (Athens, Greece), V. Vassilakopoulou (Athens, Greece), E. Mizi (Athens, Greece), S. Theocharis (Athens, Greece), T. Vassilakopoulos (Athens, Greece)
Resolvin E1 and E3 dampens asthmatic inflammation in a murine model M. Sato (Gunma, Japan), H. Aoki-Saito (Gunma, Japan), M. Yatomi (Gunma, Japan), H. Tsurumaki (Gunma, Japan), Y. Koga (Gunma, Japan), N. Sunaga (Gunma, Japan), T. Maeno (Gunma, Japan), K. Dobashi (Gunma, Japan), S. Shuto (Hokkaido, Japan), M. Yamada (Gunma, Japan), T. Hisada (Gunma, Japan)
Characterisation of type two immune responses in a murine model of allergic airway disease N. Kobold (London, United Kingdom), B. Dekkak (London, United Kingdom), P. Flajolet (London, United Kingdom), D. Patel (London, United Kingdom), R. Snelgrove (London, United Kingdom), M. Belvisi (Gothenburg, Sweden), M. Birrell (Gothenburg, Sweden)
Evaluating a CD63 assay as a biomarker for SYK inhibitor activity D. Lamb (Biberach an der Riss, Germany), K. Sewald (Hannover, Germany), E. Benediktus (Biberach an der Riss, Germany), A. Braun (Hannoveran der Riss, Germany)
Profiling the impact of two JAK inhibitors in a pre-clinical model of allergic asthma J. Pinkerton (London, United Kingdom), B. Dekkak (London, United Kingdom), D. Zervas (London, United Kingdom), T. Markou (London, United Kingdom), A. Borde (Gothenburg, Sweden), A. Cavallin (Gothenburg, Sweden), T. Ericsson (Gothenburg, Sweden), R. Hendrickx (Gothenburg, Sweden), A. Aurell Holmberg (Gothenburg, Sweden), J. Steele (Gothenburg, Sweden), M. Belvisi (Gothenburg, Sweden), M. Birrell (Gothenburg, Sweden)
In vitro and in vivo characterisation of the novel neutrophil elastase inhibitor BI 1323495 S. Kreideweiss (Biberach, Germany), A. Schuler-Metz (Biberach, Germany), C. Gnamm (Biberach, Germany), S. Peters (Biberach, Germany), T. Oost (Biberach, Germany)
Long-acting bronchodilators improve lipopolysaccharide-induced swine airway hypersecretion as well as the abnormal acidification in pH H. Aritake (Mizusawa, Japan), T. Tamada (Sendai, Japan), K. Murakami (Sendai, Japan), S. Gamo (Sendai, Japan), M. Nara (Sendai, Japan), H. Sugiura (Sendai, Japan), M. Ichinose (Sendai, Japan)
Beclomethasone, formoterol and glycopyrronium: effect on an ex vivo model of COPD exacerbation L. Calzetta (Rome, Italy), B. Ritondo (Rome, Italy), F. Cavalli (Rome, Italy), M. Matino (Rome, Italy), M. Cazzola (Rome, Italy), P. Rogliani (Rome, Italy)
Plant protease inhibitors compared to corticosteroids in mice with Asthma-COPD J. João (são paulo, Brazil), J. Barbosa (são paulo, Brazil), L. Da Silva (são paulo, Brazil), T. Dos Santos (são paulo, Brazil), L. Camargo (são paulo, Brazil), E. De Campos (são paulo, Brazil), T. Galil (são paulo, Brazil), B. Saraiva- Romanholo (são paulo, Brazil), S. Bezerra (são paulo, Brazil), S. Hamaguchi (são paulo, Brazil), M. Martins (são paulo, Brazil), M. Olivo (são paulo, Brazil), R. Righetti (são paulo, Brazil), I. Tibério (são paulo, Brazil), E. Leick (são paulo, Brazil)
The effects of Nrf2 activators and oxidative stress on COPD alveolar macrophages J. Li (Manchester (Greater Manchester), United Kingdom), J. Baker (Manchester (Greater Manchester), United Kingdom), C. Murray (Manchester (Greater Manchester), United Kingdom), N. Cooper (Manchester (Greater Manchester), United Kingdom), C. Lucas (Manchester (Greater Manchester), United Kingdom), C. Fox (Manchester (Greater Manchester), United Kingdom), D. Singh (Manchester (Greater Manchester), United Kingdom), S. Lea (Manchester (Greater Manchester), United Kingdom)
Glucocorticoid-induced adrenal suppression and metabolic syndrome in glucocorticoid treated AECOPD patients related to different gene polymorphisms of the glucocorticoid receptor gene P. Sivapalan (Hellerup, Denmark), S. W. Borresen (Copenhagen, Denmark), J. Eklöf (Hellerup, Denmark), M. Klose (Copenhagen, Denmark), T. Wilcke (Hellerup, Denmark), U. Feldt-Rasmussen (Copenhagen, Denmark), M. Rossing (Copenhagen, Denmark), F. S. Holm (Hellerup, Denmark), R. L. Marvig (Copenhagen, Denmark), N. R. Jørgensen (Copenhagen, Denmark), N. Seershom (Hellerup, Denmark), T. S. Eriksen (Hellerup, Denmark), J. Vestbo (Manchester, United Kingdom), J. Jensen (Copenhagen, Denmark)