Influence of nebulized drugs on ciliary activity in vitro

M. Boon, M. Jorissen, M. Proesmans, M. Jaspers, K. De Boeck (Leuven, Belgium)

Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Session: Preclinical models for the development of new drugs for respiratory diseases
Session type: Thematic Poster Session
Number: 685

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Boon, M. Jorissen, M. Proesmans, M. Jaspers, K. De Boeck (Leuven, Belgium). Influence of nebulized drugs on ciliary activity in vitro. Eur Respir J 2013; 42: Suppl. 57, 685

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
In vivo efficacy of CHF6001, an inhaled PDE4 inhibitor with a wide therapeutic window
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014


New nasal spray stimulates ciliary activity in vitro
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015


Effect of the combination of doxofylline and montelukast on LPS-induced leukocyte migration to the lung
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014

In vitro pharmacological characterization of two novel dual-acting MABA compounds (LAS190792 and LAS191351)
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014

Bronchoprotective activity and safety assessment of two novel dual-acting MABA compounds (LAS190792 and LAS191351) in dogs
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014

In vitro characterization of a novel inhaled PI3Kd inhibitor LAS194223
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

Effect of diminazene on monocrotalin-induced pulmonary hypertension rat model
Source: International Congress 2015 – Pulmonary hypertension: novel insights into the biology of the disease
Year: 2015

Pharmacological profile of a novel, potent and oral TRPA1 antagonist. Characterization in a preclinical model of induced cough
Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis
Year: 2015

In vitro profile of the new inhaled pan-JAK inhibitor LAS194046
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

Effect of inhaled beclomethasone or placebo on brain stem activity in a patient chronically treated with steroids - Preliminary report
Source: International Congress 2015 – New data on established treatments for asthma and COPD
Year: 2015


Fast, efficient and realistic in vitro delivery of inhaled drugs to pulmonary cells: Application to the proteasome inhibitor bortezomib
Source: Annual Congress 2013 –Cutting edge: drug delivery to the airways
Year: 2013

Prospects for new compounds tiosemikarbazonami class to create drugs with antituberculosis activity
Source: International Congress 2014 – Tuberculosis: diagnosis
Year: 2014

CHI-91040, a novel inhaled p38α inhibitor, counteracts lung inflammation induced by IL-1β in the rat
Source: International Congress 2016 – ILD: from the bench to the bedside
Year: 2016

In vitro comparison of dose accuracy of two budesonide/formoterol dry powder inhalers
Source: International Congress 2015 – New data on established treatments for asthma, COPD and bronchiectasis
Year: 2015


Simulation of particle deposition in the human airways
Source: Annual Congress 2013 –Airway calibre, airway challenge and assessment of oxygenation
Year: 2013


Preclinical characterization of CPL-302-201, a novel, highly potent and selective PI3Kδ inhibitor for the treatment of inflammatory disorders
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

The novel elastase inhibitor BAY 85-8501: Bioavailability and Food effect study to evaluate pharmacokinetics of tablet formulations
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014


Development of a novel nano-sized carrier system for aeroseol drug delivery (EGE University translational pulmonology research group)
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015

RP6503, a novel and selective PI3K δ/gamma inhibitor, potentiates the effect of steroids in pre-clinical models of COPD
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

The effects of intra-nasally administered anti-inflammatory compounds in a mouse model of acute COPD exacerbations
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013