Preclinical models for the development of new drugs for respiratory diseases

Thematic Poster Session
Chairs: M. Belvisi (London, United Kingdom), R. Gosens (Groningen, Netherlands), G. Lungarella (Siena, Italy), K.F. Chung (London, United Kingdom)
LATE-BREAKING ABSTRACT: Stable isotope labelled amino acid culturing: a novel approach to identify pathways involved in MIF signalling
K. Russell, K. Heesom, S. Hall, S. Johnston, P. Barnes, I. Adcock (London, Bristol, Stevenage, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Effects of tobacco smoke and poly IC, alone and in combination, on mouse lung pathology
A. Young, J. Dlugozima, P. Woodman, M. Foster, A. Connolly, V. Russell (Slough, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
The effects of intra-nasally administered anti-inflammatory compounds in a mouse model of acute COPD exacerbations
V. Russell, A. Connolly, J. Dlugozima, P. Woodman, A. Young (Stoke Poges, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Endothelin-1-mediated contraction of mouse small airways is resistant to salbutamol, but sensitive to rosiglitazone
J. Bourke, C. Donovan, M. FitzPatrick (Parkville, Australia)
Congress or journal article abstract
Congress or journal article abstract
Black widow spider toxin, alpha-latrotoxin, contracts large and small airways in different species
C. Donovan, A. Faiz, B. G. Oliver, J. L. Black, B. E. McParland, J. K. Burgess, J. E. Bourke (Parkville, Glebe, Darlington, Australia)
Congress or journal article abstract
Congress or journal article abstract
IL33 and TNFalpha synergistically enhance store operated Ca2+ entry in cultured human airway smooth muscle cells
B. Liu, C. Nelson, I. Hall (Nottingham, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
In-vitro bronchodilator activity clitoria ternatea and A. precatorius
R. Patil, D. Taur, R. Patil, D. Ahirwar (Malegaon (Bk) Tal- Baramati, Kharadi, Pune, Bilaspur, India)
Congress or journal article abstract
Congress or journal article abstract
Glucocorticoids and indacaterol regulated gene expressions profiling in human bronchial epithelial cells
T. Joshi, M. Johnson, R. Newton, M. Giembycz (Calgary, Canada; Uxbridge, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Oral administration of saccharomyces cerevisiae inhibits the allergic airway response in mice
M. Borges, V. Fonseca, T. Milani, A. P. Carvalho, A. Gozzi, R. Prado, V. Bonato, F. Martins, E. Vianna (Ribeirão Preto, Belo Horizonte, Brazil)
Congress or journal article abstract
Congress or journal article abstract
Evaluation of bronchodilator activity of A. precatorius leaves
R. Patil, D. Taur, R. Patil (Kharadi, Pune, Malegaon BK, Baramati, District- Pune, India)
Congress or journal article abstract
Congress or journal article abstract
RNA-seq analysis of transforming growth factor-beta-induced glucocorticoid resistance in human bronchial epithelial cells
C. Keenan, G. Lopez-Campos, S. Salem, T. Harris, M. Schuliga, C. Johnstone, A. Stewart (Parkville, East Melbourne, Australia)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Compound A (CpdA) suppressed production of corticosteroid-resistant chemokines via GR-independent mechanisms in airway smooth muscle (ASM) cells
A. Gavrila, L. Chachi, O. Tliba, C. Brightling, Y. Amrani (Leicester, United Kingdom; Philadelphia, United States Of America)
Congress or journal article abstract
Congress or journal article abstract
Nintedanib reduces bleomycin-induced lung inflammation and fibrosis in mice
L. Wollin, I. Maillet, V. Quesniaux, B. Ryffel (Biberach, Germany; Orleans, France)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
PBI-compound, a novel first-in-class anti-fibrotic compound, reduces lung fibrosis in the bleomycin-induced lung fibrosis model: A comparative study with pirfenidone
L. Gagnon, M. Tremblay, F. Sarra-Bournet, L. Gervais, S. Abbott, J. S. Duceppe, B. Zacharie, C. Penney, P. Laurin, B. Grouix (Laval, Canada)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Effect of doxofylline on LPS-induced leukocyte migration to the lung
Y. Vasquez, F. Man, C. Page (London, United Kingdom)
Congress or journal article abstract
Congress or journal article abstract
Influence of nebulized drugs on ciliary activity in vitro
M. Boon, M. Jorissen, M. Proesmans, M. Jaspers, K. De Boeck (Leuven, Belgium)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Perflubron enhances mucin plug clearance in vitro in the presence of natural surfactant
M. Al-Saiedy, E. Nelson, T. El-Mays, M. Amrein, F. Green (Calgary, Canada)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Investigating the role of prostaglandin D2 in airway sensory nerve firing: Relevance to disease
S. Maher, M. Birrell, J. Adcock, M. Wortley, S. Bonvini, M. Grace, M. Belvisi (London, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Validation of a hypertussive model of cough in the rabbit
E. Clay, D. Spina, C. Page (London, United Kingdom)
Congress or journal article abstractE-poster
Congress or journal article abstractE-poster
Pulmonary alveolar proteinosis: iPS derived macrophages as in-vitro disease model and potential source for novel gene and cell therapies
C. Happle, N. Lachmann, M. Wetzke, D. Lüttge, M. Ackermann, A. Mucci, J. Skuljec, S. Merkert, A. Schambach, T. Moritz, G. Hansen (Hannover, Germany)
Congress or journal article abstract
Congress or journal article abstract