Decreased levels of secretory leucoprotease inhibitor in the pseudomonas -infected cystic fibrosis lung are due to neutrophil elastase degradation Source: Annual Congress 2009 - Airway inflammation and host defence Year: 2009
Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-β kinase pathway Source: Eur Respir J 2003; 21: 574-581 Year: 2003
Secretory leucoprotease inhibitor (SLPI) inhibits IL-8 expression induced by double-stranded RNA in airway epithelial cells Source: Annual Congress 2008 - Airway cell biology Year: 2008
Matrix metalloproteinase inhibitor inhibits lipopolysaccharide-induced goblet-cell hyperplasia in rat airway Source: Eur Respir J 2002; 20: Suppl. 38, 572s Year: 2002
SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition Source: Eur Respir J 2011; 37: 1083-1090 Year: 2011
Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis Source: Annual Congress 2008 - Management of idiopathic pulmonary fibrosis: what can we learn from the pathophysiology? Year: 2008
Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 29s Year: 2004
A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice Source: Eur Respir J 2012; 40: 1475-1482 Year: 2012
MSCS ameliorate elastase induced emphysema by suppressing IL-1b, inducing growth factors and proteinase inhibitors Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung Year: 2009
miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production Source: Eur Respir J 2015; 46: 1350-1360 Year: 2015
The effect of sputum processing on tumour necrosis factor (TNFα), secretory leukoprotease inhibitor (SLPI), interleukin-6 and leukotriene-B4 (LTB4 ) in chronic bronchitis and bronchiectasis Source: Eur Respir J 2001; 18: Suppl. 33, 364s Year: 2001
Roflumilast potently inhibits CXCL1 mediated neutrophil migration in COPD patients Source: Annual Congress 2011 - COPD: clinical studies and animal cell models Year: 2011
MMP-12 activates protease activated receptor (PAR)-1, upregulates placenta growth factor and leads to pulmonary emphysema Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium Year: 2018
Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis Source: Eur Respir J 2015; 46: 384-394 Year: 2015
6-aminonicotinamide ameliorates pulmonary fibrosis by suppressing the TGF-beta1 activated Smad signalling pathway Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020
The chemokine decoy PA401 decreases interleukin-8 and chemotactic activity of cystic fibrosis airway samples Source: Annual Congress 2013 –Cystic fibrosis: basic and applied science Year: 2013
Peroxiredoxin 6 attenuates lipopolysaccharide-induced plasminogen activatro inhibitor 1 expression by regulating autophagy Source: Annual Congress 2012 - Lung injury and repair: reactive oxygen species and beyond Year: 2012
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Nintedanib prevents IL-6-mediated secretion of CCL-18 in alternatively activated macrophages and transition of fibroblasts to myofibroblasts Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis Year: 2017
Inhibition of LPS-induced cytokine/chemokine production from human lung macrophages by roflumilast is enabled by autocrine PGE2 Source: Annual Congress 2010 - Macrophages: cell biology and disease-specific characteristics Year: 2010