October

Objective cough frequency monitoring in real-world practice Ji-Hyang Lee, Woo-Jung Song, Eva Millqvist, Alyn H. Morice ERJ Open Res, 7 (4) 00545-2021; 10.1183/23120541.00545-2021
The Children's Anti-inflammatory Reliever (CARE) study: a protocol for a randomised controlled trial of budesonide-formoterol as sole reliever therapy in children with mild asthma Lee Hatter, Pepa Bruce, Mark Holliday, Augustus J. Anderson, Irene Braithwaite, Andrew Corin, Allie Eathorne, Arthur Grimes, Matire Harwood, Thomas Hills, Ciléin Kearns, Kyley Kerse, John Martindale, Barney Montgomery, Lynn Riggs, Davitt Sheahan, Nick Shortt, Katja Zazulia, Mark Weatherall, David McNamara, Catherine A. Byrnes, Andrew Bush, Stuart R. Dalziel, Richard Beasley ERJ Open Res, 7 (4) 00271-2021; 10.1183/23120541.00271-2021
Outcomes and characteristics of COVID-19 patients treated with continuous positive airway pressure/high-flow nasal oxygen outside the intensive care setting Dominic L. Sykes, Michael G. Crooks, Khaing Thu Thu, Oliver I. Brown, Theodore J.P. Tyrer, Jodie Rennardson, Catherine Littlefield, Shoaib Faruqi ERJ Open Res, 7 (4) 00318-2021; 10.1183/23120541.00318-2021
Exhaled volatile organic compounds and lung microbiome in COPD: a pilot randomised controlled trial Divya Mohan, Holly R. Keir, Hollian Richardson, David Mayhew, Joseph Boyer, Marc P. van der Schee, Max D. Allsworth, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers ERJ Open Res, 7 (4) 00253-2021; 10.1183/23120541.00253-2021
Lung function, COPD and Alternative Healthy Eating Index in US adults Kirstie Ducharme-Smith, Gustavo Mora-Garcia, Francisca de Castro Mendes, Maria Stephany Ruiz-Diaz, Andre Moreira, Rodrigo Villegas, Vanessa Garcia-Larsen ERJ Open Res, 7 (4) 00927-2020; 10.1183/23120541.00927-2020
Feasibility and clinical utility of ambulatory cough monitoring in an outpatient clinical setting: a real-world retrospective evaluation Anne E. Vertigan, Sarah L. Kapela, Surinder S. Birring, Peter G. Gibson ERJ Open Res, 7 (4) 00319-2021; 10.1183/23120541.00319-2021
Within-session variability as quality control for oscillometry in health and disease Louise M. Harkness, Kieran Patel, Farid Sanai, Sandra Rutting, Alice M. Cottee, Claude S. Farah, Robin E. Schoeffel, Gregory G. King, Cindy Thamrin ERJ Open Res, 7 (4) 00074-2021; 10.1183/23120541.00074-2021
Effect of a day-trip to altitude (2500 m) on exercise performance in pulmonary hypertension: randomised crossover trial Simon R. Schneider, Laura C. Mayer, Mona Lichtblau, Charlotte Berlier, Esther I. Schwarz, Stéphanie Saxer, Lu Tan, Michael Furian, Konrad E. Bloch, Silvia Ulrich ERJ Open Res, 7 (4) 00314-2021; 10.1183/23120541.00314-2021
The angiostatic peptide endostatin enhances mortality risk prediction in pulmonary arterial hypertension Catherine E. Simpson, Megan Griffiths, Jun Yang, Melanie K. Nies, R. Dhananjay Vaidya, Stephanie Brandal, Lisa J. Martin, Michael W. Pauciulo, Katie A. Lutz, Anna W. Coleman, Eric D. Austin, D. Dunbar Ivy, William C. Nichols, Allen D. Everett, Paul M. Hassoun, Rachel L. Damico ERJ Open Res, 7 (4) 00378-2021; 10.1183/23120541.00378-2021
Health service utilisation associated with chronic breathlessness: random population sample David C. Currow, Sungwon Chang, Magnus Ekström, Ann Hutchinson, Tim Luckett, Slavica Kochovska, Phillipa Hay, Stephen Touyz, Eleonora Dal Grande, Miriam J. Johnson ERJ Open Res, 7 (4) 00415-2021; 10.1183/23120541.00415-2021
Improvement in exercise capacity after a modified Potts shunt in an adult patient with pulmonary arterial hypertension Petr Symersky, Samara M.A. Jansen, Suzanne K. Kamminga, Lilian J. Meijboom, Erik J. Lust, Pirooz Eghtesady, Robert M. Grady, Harm J. Bogaard ERJ Open Res, 7 (4) 00287-2021; 10.1183/23120541.00287-2021
Dyspnoea and clinical outcome in critically ill patients receiving noninvasive support for COVID-19 respiratory failure: post hoc analysis of a randomised clinical trial Luca S. Menga, Domenico Luca Grieco, Tommaso Rosà, Melania Cesarano, Luca Delle Cese, Cecilia Berardi, Gabriele Pintaudi, Eloisa Sofia Tanzarella, Salvatore L. Cutuli, Gennaro De Pascale, Salvatore Maurizio Maggiore, Massimo Antonelli ERJ Open Res, 7 (4) 00418-2021; 10.1183/23120541.00418-2021
Protein levels, air pollution and vitamin D deficiency: links with allergy Yong Song, E. Haydn Walters, Michael J. Abramson, Gayan Bowatte, Dinh S. Bui, Jennifer Perret, Iain Feather, Luke D. Knibbs, Richard Wilson, David S. Nichols, Shyamali C. Dharmage, Graeme R. Zosky ERJ Open Res, 7 (4) 00237-2021; 10.1183/23120541.00237-2021
Rising COVID-19 related acute pulmonary emboli but falling national chronic thromboembolic pulmonary hypertension referrals from a large national dataset Joseph Newman, Iryna Boubriak, David Jenkins, Choo Ng, Alessandro Ruggiero, Nicholas Screaton, John Cannon, Mark Toshner ERJ Open Res, 7 (4) 00431-2021; 10.1183/23120541.00431-2021
Impact of the SARS-CoV-2 pandemic on cystic fibrosis centres and care: survey results from US centres Marianne S. Muhlebach, Fiona Cunningham, John J. LiPuma, Juyan J. Zhou, Lisa Saiman ERJ Open Res, 7 (4) 00249-2021; 10.1183/23120541.00249-2021
Mobile video directly observed therapy can be used to improve at-home inhaler technique in children with asthma Michael D. Shields, James McElnay ERJ Open Res, 7 (4) 00463-2021; 10.1183/23120541.00463-2021
Lower airway clinical outcome measures for use in primary ciliary dyskinesia research: a scoping review Florian Gahleitner, James Thompson, Claire L. Jackson, Jana F. Hueppe, Laura Behan, Eleonora Dehlink, Myrofora Goutaki, Florian Halbeisen, Ana Paula L. Queiroz, Guillaume Thouvenin, Claudia E. Kuehni, Philipp Latzin, Jane S. Lucas, Bruna Rubbo ERJ Open Res, 7 (4) 00320-2021; 10.1183/23120541.00320-2021
Individual trajectory-based care for COPD: getting closer, but not there yet Nicolas Roche, Philippe Devillier, Patrick Berger, Arnaud Bourdin, Daniel Dusser, Jean-François Muir, Yan Martinat, Philippe Terrioux, Bruno Housset ERJ Open Res, 7 (4) 00451-2021; 10.1183/23120541.00451-2021
Home monitoring of physiology and symptoms to detect interstitial lung disease exacerbations and progression: a systematic review Malik A. Althobiani, Rebecca A. Evans, Jaber S. Alqahtani, Abdulelah M. Aldhahir, Anne-Marie Russell, John R. Hurst, Joanna C. Porter ERJ Open Res, 7 (4) 00441-2021; 10.1183/23120541.00441-2021
Is asthma associated with COVID-19 infection? A UK Biobank analysis Caroline J. Lodge, Alice Doherty, Dinh S. Bui, Raisa Cassim, Adrian J. Lowe, Alvar Agusti, Melissa A. Russell, Shyamali C. Dharmage ERJ Open Res, 7 (4) 00309-2021; 10.1183/23120541.00309-2021
Quantification of aerosol dispersal from suspected aerosol-generating procedures Runar Strand-Amundsen, Christian Tronstad, Ole Elvebakk, Tormod Martinsen, Marius Dybwad, Egil Lingaas, Tor Inge Tønnessen ERJ Open Res, 7 (4) 00206-2021; 10.1183/23120541.00206-2021
Salivary detection of COVID-19: clinical performance of oral sponge sampling for SARS-CoV-2 testing Jacques Boutros, Jonathan Benzaquen, Charles Hugo Marquette, Marius Ilié, Mickelina Labaky, Didier Benchetrit, Thibaut Lavrut, Sylvie Leroy, Richard Chemla, Michel Carles, Virginie Tanga, Charlotte Maniel, Olivier Bordone, Maryline Allégra, Virginie Lespinet, Julien Fayada, Jennifer Griffonnet, Véronique Hofman, Paul Hofman ERJ Open Res, 7 (4) 00396-2021; 10.1183/23120541.00396-2021
Factors for severe outcomes following SARS-CoV-2 infection in people with cystic fibrosis in Europe Andreas Jung, Annalisa Orenti, Fiona Dunlevy, Elina Aleksejeva, Egil Bakkeheim, Vladimir Bobrovnichy, Siobhán B. Carr, Carla Colombo, Harriet Corvol, Rebecca Cosgriff, Géraldine Daneau, Deniz Dogru, Pavel Drevinek, Andrea Dugac Vukic, Isabelle Fajac, Alice Fox, Stojka Fustik, Vincent Gulmans, Satenik Harutyunyan, Elpis Hatziagorou, Irena Kasmi, Hana Kayserová, Elena Kondratyeva, Uros? Krivec, Halyna Makukh, Kestutis Malakauskas, Edward F. McKone, Meir Mei-Zahav, Isabelle de Monestrol, Hanne Vebert Olesen, Rita Padoan, Tsitsino Parulava, Maria Dolores Pastor-Vivero, Luísa Pereira, Guergana Petrova, Andreas Pfleger, Liviu Pop, Jacqui G. van Rens, Milan Rodic´, Marc Schlesser, Valérie Storms, Oxana Turcu, Lukasz Woz´niacki, Panayiotis Yiallouros, Anna Zolin, Damian G. Downey, Lutz Naehrlich ERJ Open Res, 7 (4) 00411-2021; 10.1183/23120541.00411-2021
Working memory training efficacy in COPD: the randomised, double-blind, placebo-controlled Cogtrain trial Martijn van Beers, Sarah W. Mount, Katrijn Houben, Harry R. Gosker, Lisanne Schuurman, Frits M.E. Franssen, Daisy J.A. Janssen, Annemie M.W.J. Schols ERJ Open Res, 7 (4) 00475-2021; 10.1183/23120541.00475-2021
The clinical utility of forced oscillation technique during hospitalisation in patients with exacerbation of COPD Jaber S. Alqahtani, Ahmad M. Al Rajeh, Abdulelah M. Aldhahir, Yousef S. Aldabayan, John R. Hurst, Swapna Mandal ERJ Open Res, 7 (4) 00448-2021; 10.1183/23120541.00448-2021
Acceptability of capnography-assisted respiratory therapy: a new mind–body intervention for COPD Anna Migliore Norweg, Anne Skamai, Simona C. Kwon, Jonathan Whiteson, Kyle MacDonald, Francois Haas, Eileen G. Collins, Roberta M. Goldring, Joan Reibman, Yinxiang Wu, Greg Sweeney, Alicia Pierre, Andrea B. Troxel, Linda Ehrlich-Jones, Naomi M. Simon ERJ Open Res, 7 (4) 00256-2021; 10.1183/23120541.00256-2021
Neutrophil-to-lymphocyte ratio, blood eosinophils and COPD exacerbations: a cohort study Jens Ellingsen, Christer Janson, Kristina Bröms, Karin Lisspers, Björn Ställberg, Marieann Högman, Andrei Malinovschi ERJ Open Res, 7 (4) 00471-2021; 10.1183/23120541.00471-2021
Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study Gang Wang, Jenny Hallberg, Dimitrios Charalampopoulos, Maribel Casas Sanahuja, Robab Breyer-Kohansal, Arnulf Langhammer, Raquel Granell, Judith M. Vonk, Annemiek Mian, Núria Olvera, Lisbeth Mølgaard Laustsen, Eva Rönmark, Alicia Abellan, Alvar Agusti, Syed Hasan Arshad, Anna Bergström, H. Marike Boezen, Marie-Kathrin Breyer, Otto Burghuber, Anneli Clea Bolund, Adnan Custovic, Graham Devereux, Gavin C. Donaldson, Liesbeth Duijts, Ana Esplugues, Rosa Faner, Ferran Ballester, Judith Garcia-Aymerich, Ulrike Gehring, Sadia Haider, Sylvia Hartl, Helena Backman, John W. Holloway, Gerard H. Koppelman, Aitana Lertxundi, Turid Lingaas Holmen, Lesley Lowe, Sara M. Mensink-Bout, Clare S. Murray, Graham Roberts, Linnea Hedman, Vivi Schlünssen, Torben Sigsgaard, Angela Simpson, Jordi Sunyer, Maties Torrent, Stephen Turner, Maarten Van den Berge, Roel C.H. Vermeulen, Sigrid Anna Aalberg Vikjord, Jadwiga A. Wedzicha, Anke H. Maitland van der Zee, Erik Melén ERJ Open Res, 7 (4) 00457-2021; 10.1183/23120541.00457-2021
Endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome Etienne-Marie Jutant, Guillaume Voiriot, Vincent Labbé, Laurent Savale, Hayat Mokrani, Patrick Van Dreden, Grigorios Gerotziafas, Muriel Fartoukh ERJ Open Res, 7 (4) 00496-2021; 10.1183/23120541.00496-2021
Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model Yoko Miura, Hirotsugu Ohkubo, Akio Niimi, Satoshi Kanazawa ERJ Open Res, 7 (4) 00345-2021; 10.1183/23120541.00345-2021
Sarcoidosis in Iceland: a nationwide study of epidemiology, clinical picture and environmental exposure Sigríður Ólína Haraldsdóttir, Jon Gunnlaugur Jonasson, Kristin Bara Jorundsdottir, Haraldur Jon Hannesson, Thorarinn Gislason, Bjorn Gudbjornsson ERJ Open Res, 7 (4) 00550-2021; 10.1183/23120541.00550-2021
The risk of respiratory tract infections and antibiotic use in a general population and among people with asthma Marta A. Kisiel, Xingwu Zhou, Eythor Björnsson, Mathias Holm, Anna Dahlman-Höglund, Juan Wang, Cecilie Svanes, Dan Norbäck, Karl A. Franklin, Andrei Malinovschi, Ane Johannessen, Vivi Schlünssen, Christer Janson ERJ Open Res, 7 (4) 00429-2021; 10.1183/23120541.00429-2021
Benefits and risks of bronchoalveolar lavage in severe asthma in children Raja Ben Tkhayat, Jessica Taytard, Harriet Corvol, Laura Berdah, Blandine Prévost, Jocelyne Just, Nadia Nathan ERJ Open Res, 7 (4) 00332-2021; 10.1183/23120541.00332-2021
Breastfeeding and risk of childhood asthma: a systematic review and meta-analysis Mike Xue, Emily Dehaas, Nagendra Chaudhary, Paul O'Byrne, Imran Satia, Om P. Kurmi ERJ Open Res, 7 (4) 00504-2021; 10.1183/23120541.00504-2021
Clinical value of bronchodilator response for diagnosing asthma in steroid-naïve adults Leena E. Tuomisto, Pinja Ilmarinen, Lauri Lehtimäki, Onni Niemelä, Minna Tommola, Hannu Kankaanranta ERJ Open Res, 7 (4) 00293-2021; 10.1183/23120541.00293-2021
Pilot study on nocturnal monitoring of crackles in children with pneumonia Wilfried Nikolaizik, Lisa Wuensch, Monika Bauck, Volker Gross, Keywan Sohrabi, Andreas Weissflog, Olaf Hildebrandt, Ulrich Koehler, Stefanie Weber ERJ Open Res, 7 (4) 00284-2021; 10.1183/23120541.00284-2021
In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by a₁-antitrypsin Padraig Hawkins, Thomas McEnery, Claudie Gabillard-Lefort, David A. Bergin, Bader Alfawaz, Vipatsorn Shutchaidat, Paula Meleady, Michael Henry, Orla Coleman, Mark Murphy, Noel G. McElvaney, Emer P. Reeves ERJ Open Res, 7 (4) 00234-2021; 10.1183/23120541.00234-2021
High-flow oxygen therapy versus noninvasive ventilation: a randomised physiological crossover study of alveolar recruitment in acute respiratory failure Elise Artaud-Macari, Michael Bubenheim, Gurvan Le Bouar, Dorothée Carpentier, Steven Grangé, Déborah Boyer, Gaëtan Béduneau, Benoit Misset, Antoine Cuvelier, Fabienne Tamion, Christophe Girault ERJ Open Res, 7 (4) 00373-2021; 10.1183/23120541.00373-2021
Cross-talk of inflammatory mediators and airway epithelium reveals the cystic fibrosis transmembrane conductance regulator as a major target Filipa B. Simões, Arthur Kmit, Margarida D. Amaral ERJ Open Res, 7 (4) 00247-2021; 10.1183/23120541.00247-2021
Family planning, pregnancy and birth in women with lung conditions: a worldwide survey Clare Williams, Barbara Johnson, Peter G. Middleton, Vibeke Backer, Peter G. Gibson, Gill Hollis, Courtney Coleman ERJ Open Res, 7 (4) 00357-2021; 10.1183/23120541.00357-2021
Lung cancer mortality in Europe and the USA between 2000 and 2017: an observational analysis Chinmay Jani, Dominic C. Marshall, Harpreet Singh, Richard Goodall, Joseph Shalhoub, Omar Al Omari, Justin D. Salciccioli, Carey C. Thomson ERJ Open Res, 7 (4) 00311-2021; 10.1183/23120541.00311-2021
Controlled versus free breathing for multiple-breath nitrogen washout in asthma Blake M. Handley, Jack Bozier, Edward Jeagal, Sandra Rutting, Robin E. Schoeffel, Paul D. Robinson, Gregory G. King, Stephen Milne, Cindy Thamrin ERJ Open Res, 7 (4) 00487-2021; 10.1183/23120541.00487-2021
Discontinuation of benralizumab in Canadian patients with severe eosinophilic asthma Stephen G. Noorduyn, Karissa Johnston, Kathy Osenenko, Niroshan Sriskandarajah, Alain Gendron, Lawrence Mbuagbaw ERJ Open Res, 7 (4) 00465-2021; 10.1183/23120541.00465-2021
Granulomatous–lymphocytic interstitial lung disease: an international research prioritisation John R. Hurst, S. Hamza Abbas, Heba M. Bintalib, Tiago M. Alfaro, Ulrich Baumann, Siobhan O. Burns, Alison Condliffe, Jesper R. Davidsen, Børre Fevang, Andrew R. Gennery, Filomeen Haerynck, Joseph Jacob, Stephen Jolles, Olivia Lamers, Anne Bergeron, Marion Malphettes, Véronique Meignin, Cinzia Milito, Tomas Milota, Martine Pergent, Antje Prasse, Isabella Quinti, Elisabetta Renzoni, Anna Sediva, Daiana Stolz, Bas Smits, Friedolin Strauss, Annick A.J.M. van de Ven, Joris van Montfrans, Klaus Warnatz ERJ Open Res, 7 (4) 00467-2021; 10.1183/23120541.00467-2021
Assessing usability of QIAreach QuantiFERON-TB platform in a high tuberculosis prevalence, low-resource setting Conceptor Kaaba, Maria Ruperez, Barry Kosloff, Nduku Ndunda, Kwame Shanaube, Helen Ayles ERJ Open Res, 7 (4) 00511-2021; 10.1183/23120541.00511-2021
“Interferon-? liposome: a new system to improve drug delivery in the treatment of lung cancer”. Maysa Alhawamdeh, Mohammad Isreb, Abid Aziz, Badie K. Jacob, Diana Anderson and Mojgan Najafzadeh. ERJ Open Res 2021; 7: 00555-2020. ERJ Open Res, 7 (4) 50555-2020; 10.1183/23120541.50555-2020
“Quit attempts and tobacco abstinence in primary care patients: follow-up of a pragmatic, two-arm cluster randomised controlled trial on brief stop-smoking advice – ABC versus 5As”. Sabrina Kastaun, Wolfgang Viechtbauer, Verena Leve, Jaqueline Hildebrandt, Christian Funke, Stephanie Klosterhalfen, Diana Lubisch, Olaf Reddemann, Tobias Raupach, Stefan Wilm and Daniel Kotz. ERJ Open Res 2021; 7: 00224-2021. ERJ Open Res, 7 (4) 50224-2021; 10.1183/23120541.50224-2021