In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by a1 -antitrypsin
Padraig Hawkins, Thomas McEnery, Claudie Gabillard-Lefort, David A. Bergin, Bader Alfawaz, Vipatsorn Shutchaidat, Paula Meleady, Michael Henry, Orla Coleman, Mark Murphy, Noel G. McElvaney, Emer P. Reeves
Source: ERJ Open Res, 7 (4) 00234-2021; 10.1183/23120541.00234-2021
Rating:
You must login to grade this presentation.
Share or cite this content
Citations should be made in the following way:
Padraig Hawkins, Thomas McEnery, Claudie Gabillard-Lefort, David A. Bergin, Bader Alfawaz, Vipatsorn Shutchaidat, Paula Meleady, Michael Henry, Orla Coleman, Mark Murphy, Noel G. McElvaney, Emer P. Reeves. In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by a1 -antitrypsin. ERJ Open Res, 7 (4) 00234-2021; 10.1183/23120541.00234-2021
You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
Related content which might interest you:
Related content which might interest you:
Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways Source: Eur Respir J 2004; 23: 496 Year: 2004
Hypoxia and reoxygenation modulate lung epithelial cell glutathione content, oxygen consumption and reactive oxygen species (ROS) production Source: Eur Respir J 2001; 18: Suppl. 33, 182s Year: 2001
IL-13 enhances GSNO reductase activity and decreases intracellular S-nitrosothiols in lung epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 103s Year: 2006
The oxygen free radical-scavenger glutathione prevents the depletion of IL-16 in human CD8 lymphocytes that is caused by tobacco-smoke components in vitro Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007
Production of superoxide anions by the NADPH oxidase in mammalian skeletal muscles Source: Eur Respir J 2001; 18: Suppl. 33, 421s Year: 2001
Role of complex I and III in the production of reactive oxygen species by mitochondria of peripheral muscle in COPD subjects Source: Annual Congress 2009 - Gas exchange and exercise in respiratory diseases Year: 2009
Hypoxia-dependent regulation of non-phagocytic NADPH oxidase NOX4 in the pulmonary vasculature Source: Eur Respir J 2007; 30: Suppl. 51, 56s Year: 2007
BALF modulates neutrophil phagocytosis and ROS production in different ways Source: Annual Congress 2009 - Airway inflammation and host defence Year: 2009
Xanthine oxidase inhibitors reduce rhinovirus induced IL-8 and GRO-α production in bronchial epithelial cells Source: Eur Respir J 2007; 30: Suppl. 51, 721s Year: 2007
Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis Source: Eur Respir J, 51 (4) 1702021; 10.1183/13993003.02021-2017 Year: 2018
Exhaled H2O2 correlates with the release of reactive oxygen species by blood phagocytes in healthy subjects Source: Eur Respir J 2002; 20: Suppl. 38, 91s Year: 2002
Altered mitochondrial reactive oxygen species (ROS) production in airway smooth muscle cells of severe asthma. Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma Year: 2019
Influence of AECOPD to ROS production in neutrophils Source: Annual Congress 2011 - COPD: human studies Year: 2011
Superoxide production by the Nox4 based NAD(P)H oxidase is increased in bronchial biopsies from asthmatic patients. Relationship to lung function Source: Eur Respir J 2004; 24: Suppl. 48, 683s Year: 2004
Mitochondrion-derived reactive oxygen species mediate mechanotransduction in A549 cells Source: Eur Respir J 2006; 28: Suppl. 50, 821s Year: 2006
Peroxynitrite and superoxide anion chemiluminescence generation during human neutrophil respiratory bursts is reduced by a synergistic combination of budesonide and the SH metabolite of erdosteine Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
Diamine oxidase activation by diphenhydramine – in vitro but no in vivo effect Source: Eur Respir J 2003; 22: Suppl. 45, 110s Year: 2003
Cytokines and reactive oxygen species (ROS) produced by alveolar macrophages (AM) in sarcoidosis Source: Eur Respir J 2001; 18: Suppl. 33, 68s Year: 2001
Apocynin reduces reactive oxygen species generation in airways of asthmatics Source: Annual Congress 2010 - New treatments for asthma and COPD Year: 2010
Budesonide reduces superoxide and peroxynitrite chemiluminescence during human neutrophil bursts Source: Eur Respir J 2004; 24: Suppl. 48, 21s Year: 2004