Research Seminars

About

Research Seminars gather a small number (20 to 100) of well-established and preferably young investigators to address scientific topics in depth and help break new ground. Research Seminars take place over two days in easy-to-reach European cities. They are scientific Seminars involving recently published work and research in progress. Participation is fully supported by the budget granted by the ERS.

Preparing for the first early pulmonary intervention studies in infants and preschool childrenwith Cystic Fibrosis

The aims of the research seminar were:

Summarise the current knowledge regarding clinical trial outcomes for infants and preschool children with cystic fibrosis
Review regulatory requirements for trial endpoints in infants and young children
Identify gaps in knowledge and information required

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Introduction - setting the scene S. Stick (Perth, Australia)
Computerised tomography (CT) – Gold standard for structural lung disease in young children with CT? H. Tiddens (Rotterdam, Netherlands)
Image analysis and scoring in young children S. Stick (Perth, Australia), H. Tiddens (Rotterdam, Netherlands)
CT dose – optimising the risk to benefit ratio M. Van Straten (, Netherlands)
Surrogate outcome measures F. Ratjen (Toronto, Canada)
Bronchoalveolar lavage (BAL) to monitor disease progression P. Sly (Herston, Australia)
Raised volume rapid thoracic compression S. Ranganathan (Parkville, Australia)
Lung Clearance Index (LCI) P. Gustafsson (Skovde, Sweden)
Spirometry P. Aurora (London, United Kingdom)
Introduction H. Tiddens (Rotterdam, Netherlands)
Workshop 3 - Pulmonary Function Tests P. Aurora (London, United Kingdom), M. Rosenfeld (Seattle, Wa, United States of America)
Workshop - A strategy to acquire the data that will satisfy regulatory bodies S. Stick (Perth, Australia)