Research Seminars

About

Research Seminars gather a small number (20 to 100) of well-established and preferably young investigators to address scientific topics in depth and help break new ground. Research Seminars take place over two days in easy-to-reach European cities. They are scientific Seminars involving recently published work and research in progress. Participation is fully supported by the budget granted by the ERS.

Metabolic Aspects of the Obstructive Sleep Apnea Syndrome (OSAS)

Insulin resistance is often associated with obstructive sleep apnoea syndrome (OSAS) and could contribute to cardiovascular risk in OSAS. Sleep loss and intermittent hypoxia could contribute to the pathogenesis of the metabolic alterations associated with obesity, a common feature of OSAS. The biology of the adipocyte is being increasingly studied, and it has been found that hypoxia negatively affects adipocyte function.

This Research Seminar aimed at discussing:

the effects of hypoxia on glucose metabolism and adipocyte function
the role of inflammatory activation in OSAS and obesity
the alarming rates of obesity and OSAS in children
the harmful effects of the metabolic syndrome in OSAS
the effects of OSAS treatment on metabolic variables
the relationship between daytime sleepiness and hormonal and inflammatory responses.

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Metabolic effects of OSAS and cardiovascular risk M. Bonsignore (Palermo, Italy)
Is OSAS a systemic disease? A. Vgontzas (Hershey, Pa, United States of America)
Obesity in children: a model for early aspects and prevention of OSAS W. Kiess (Leipzig, Germany)
Sleep-disordered breathing and metabolic alterations in children S. Verhulst (Wilrijk, Belgium)
Can CPAP reduce adverse cardiovascular and metabolic effects of OSAS? R. Tkacova (Kosice, Slovakia)
Endocrine function of adipose tissue P. Trayhurn (Liverpool, United Kingdom)
Adipose tissue and muscle insulin resistance J. Eckel (Duesseldorf, Germany)
Inflammation and vascular dysfunction B. Staels (Lille, France)
Biological Specificity of Visceral Adipose Tissue and Therapeutic Intervention F. Giorgino (Bari, Italy)
Intermittent hypoxia in sleep apnea: a cause of inflammatory activation W. McNicholas (Dublin, Ireland)
Biology of peripheral blood inflammatory cells in OSAS L. Lavie (Haifa, Israel)
Excessive daytime somnulence, obesity and inflammation A. Vgontzas (Hershey, Pa, United States of America)
The development of insulin resistance in a murine model of intermittent hypoxia C. O'Donnell (Pittsburgh, United States of America)