ERS International Congress, Paris 2018

Browse by day: Saturday, 15.09.2018 Sunday, 16.09.2018 Monday, 17.09.2018 Tuesday, 18.09.2018 Wednesday, 19.09.2018		View the presentations you missed during Congress! More than 1,700 webcasts and slide presentations, 1,600 e-posters and 4,200 abstracts from the International Congress in Paris and are now available.

Citations should be made in the following way: Authors. Title. Eur Respir J 2018; 52: Suppl. 62, abstract number.

Identification of therapeutic targets for asthma

Thematic Poster
Chairs: S. Krauss-Etschmann (Borstel, Germany), N. Reynaert (Maastricht, Netherlands), R. Bals (Homburg (Saar), Germany), H. Heijink (Groningen, Netherlands)

Download all media

Human airway trypsin-like protease stimulates differentiation of fibroblasts to myofibroblasts in human bronchial fibroblasts in vitro M. MIKI (Toyonaka, Japan), K. Miki (Toyonaka, Japan), S. Kitada (Toyonaka, Japan), Y. Takeuchi (Toyonaka, Japan), R. Tsutsumi (Tokushima, Japan), S. Yasuoka (Tokushima, Japan)
Increased endocytosis activity contributes to the enhanced TGFß-induced fibroblast to myofibroblast transition in bronchial asthma D. Ryszawy (Cracow, Poland), D. Wnuk (Cracow, Poland), N. Janik (Cracow, Poland), E. Karnas (Cracow, Poland), M. Paw (Cracow, Poland), H. Plutecka (Cracow, Poland), B. Jakiela (Cracow, Poland), Z. Madeja (Cracow, Poland), M. Michalik (Cracow, Poland)
Enhanced efficiency of phenotypic transition of asthmatic fibroblasts depends on canonical and non-canonical TGFß/Smad signaling pathways D. Wnuk (Cracow, Poland), K. Ryczek (Cracow, Poland), M. Paw (Cracow, Poland), K. Kmiotek-Wasylewska (Cracow, Poland), K. Sladek (Cracow, Poland), G. Bochenek (Cracow, Poland), M. Michalik (Cracow, Poland)
Eosinophils contribute to extracellular matrix remodeling by enhancing pulmonary fibroblasts proliferation, differentiation and extracellular matrix proteins production in asthma A. Januskevicius (Kaunas, Lithuania), I. Janulaityte (Kaunas, Lithuania), R. Gosens (Groningen, Netherlands), V. Kalinauskaite-Zukauske (Kaunas, Lithuania), R. Stonkus (Kaunas, Lithuania), K. Malakauskas (Kaunas, Lithuania)
Eosinophil outer membrane integrins and IL-5, IL-3, GM-CSF receptors expression in severe eosinophilic asthma V. Kalinauskaite-Zukauske (Kaunas, Lithuania), I. Janulaityte (Kaunas, Lithuania), A. Januskevicius (Kaunas, Lithuania), R. Stonkus (Kaunas, Lithuania), K. Malakauskas (Kaunas, Lithuania)
Eosinophils promote airway smooth muscle cells contractility and a-actin gene expression in asthma I. Janulaityte (Kaunas, Lithuania), A. Januskevicius (Kaunas, Lithuania), R. Gosens (Groningen, Lithuania), V. Kalinauskaite-Zukauske (Kaunas, Lithuania), R. Stonkus (Kaunas, Lithuania), K. Malakauskas (Kaunas, Lithuania)
Involvement of epigenetic factor in regulation of steroid resistant bronchial asthma patients R. MISHRA (LUCKNOW, India), H. Singh (LUCKNOW, India), S. Chaturvedi (LUCKNOW, India), M. Rai (LUCKNOW, India), V. Agarwal (LUCKNOW, India), R. Chaturvedi (LUCKNOW, India), Z. Hashim (LUCKNOW, India)
Corticosteroid-resistant neutrophilic airway inflammation and hyperresponsiveness caused by IL-13 E. Davies (Southampton, United Kingdom), J. Kelly (Southampton, United Kingdom), J. Whitsett (Cincinnati, United States of America), D. Davies (Southampton, United Kingdom), H. Haitchi (Southampton, United Kingdom)
Role of protein phosphatase 1 glycogen-associated regulatory subunit in asthma M. Álvarez-Santos (CDMX, Mexico), M. Alvarez-González (CDMX, Mexico), E. Eslava-De Jesus (CDMX, Mexico), Y. Pérez-Del Valle (CDMX, Mexico), J. Ambrosio (CDMX, Mexico), O. Reynoso-Ducoing (CDMX, Mexico), P. Ramos-Ramirez (Solna, Sweden), B. Bazan-Perkins (CDMX, Mexico)
Aerobic exercise reduces airway inflammation, remodeling and hyperresponsiveness by inhibiting reactive oxygen species and TGF-beta production by activated airway leukocytes: a flow cytometry approach M. Carneiro De Oliveira Jr (São Paulo, Brazil), A. Santos Dias (São José dos Campos, Brazil), A. Ligeiro De Oliveira (São Paulo, Brazil), R. De Paula Vieir (São José dos Campos, Brazil)
SOCS-JAK-STAT Signalling is Involved in the Beneficial Effects of Aerobic Exercise in a Model of HDM-Induced Asthma A. Almeida-Oliveira (São José dos Campos, Brazil), J. Comin Jonco Aquino-Junior (São José dos Campos, Brazil), H. Cristina Aquino-Santos (São Paulo, Brazil), A. Ligeiro De Oliveira (São Paulo, Brazil), R. De Paula Vieira (São Paulo, Brazil)
Blocking IL-4Ra with dupilumab prevents lung inflammation in a mouse asthma model J. Orengo (Tarrytown, United States of America), J. Allinne (Tarrytown, United States of America), A. Le Floc`h (Tarrytown, United States of America), T. Potocky (Tarrytown, United States of America), J. Kim (Tarrytown, United States of America), D. Birchard (Tarrytown, United States of America), G. Scott (Tarrytown, United States of America), Y. Bai (Tarrytown, United States of America), A. Rafique (Tarrytown, United States of America), T. Huang (Tarrytown, United States of America), J. Martin (Tarrytown, United States of America), M. Sleeman (Tarrytown, United States of America), A. Murphy (Tarrytown, United States of America)
First evidence for a gut-lung axis influencing murine lung immunity upon early life antibiotic treatment G. Jatzlauk (Borstel, Germany), S. Bartel (Borstel, Germany), S. Pfeiffer (Weihenstephan, Germany), M. Schloter (Weihenstephan/Oberschleißheim, Germany), S. Krauss-Etschmann (Borstel, Germany)
MIF antagonism restores corticosteroid sensitivity in a murine model of severe asthma v. allam (Sydney, Australia), I. Adcock (London, United Kingdom), K. Chung (London, United Kingdom), E. Morand (Clayton, Australia), J. Harris (Clayton, Australia), M. Sukkar (Sydney, Australia)
Glucocorticoids induce a shift in chemokine profile in LPS-stimulated human alveolar macrophages C. Mardh (Gothenburg, Sweden), N. Kurian (Gothenburg, Sweden), T. Ottosson (Gothenburg, Sweden)
Inhaled formulation of angiotensin-(1-7) produces lung protective effects in a model of chronic asthma. G. Magalhães (Belo Horizonte , Brazil), M. Rodrigues-Machado (Belo Horizonte , Brazil), J. Gregório (Belo Horizonte , Brazil), K. Gonzaga (Belo Horizonte , Brazil), P. Cassini (Belo Horizonte , Brazil), L. Barcelos (Belo Horizonte , Brazil), R. Santos (Belo Horizonte , Brazil), M. Campagnole-Santos (Belo Horizonte , Brazil)
Bronchial Thermoplasty and its Impact on Mast Cells in the Asthmatic Airway Wall and Smooth Muscle A. Goorsenberg (Amsterdam, Netherlands), J. D'Hooghe (Amsterdam, Netherlands), N. Ten Hacken (Amsterdam, Netherlands), E. Weersink (Amsterdam, Netherlands), J. Roelofs (Amsterdam, Netherlands), J. Annema (Amsterdam, Netherlands), P. Bonta (Amsterdam, Netherlands)
Effects of anti-IL17 on inflammation, remodeling, and oxidative stress in an experimental model of asthma exacerbated by LPS L. Camargo (São Paulo, Brazil), R. F. Righetti (São Paulo, Brazil), L. R. C. R. B. AristóTeles (São Paulo, Brazil), T. M. Santos (São Paulo, Brazil), F. C. R. Souza (São Paulo, Brazil), S. Fukuzaki (São Paulo, Brazil), M. M. Cruz (São Paulo, Brazil), M. C. Alonso-Vale (São Paulo, Brazil), B. M. Saraiva-Romanholo (São Paulo, Brazil), C. M. Prado (São Paulo, Brazil), M. A. Martins (São Paulo, Brazil), E. A. Leick (São Paulo, Brazil), I. F. L. C. Tibério (São Paulo, Brazil)
The lung microbiota changes associated with inhaled corticosteroid and azithromycin in murine model of COPD Y. Chen (Yun-lin, Taiwan), H. Hou (Taipei, Taiwan), S. Cheng (Taipei, Taiwan), H. Wang (Taipei, Taiwan), C. Yu (Taipei, Taiwan)