Inhaled formulation of angiotensin-(1-7) produces lung protective effects in a model of chronic asthma.

G. Magalhães (Belo Horizonte , Brazil), M. Rodrigues-Machado (Belo Horizonte , Brazil), J. Gregório (Belo Horizonte , Brazil), K. Gonzaga (Belo Horizonte , Brazil), P. Cassini (Belo Horizonte , Brazil), L. Barcelos (Belo Horizonte , Brazil), R. Santos (Belo Horizonte , Brazil), M. Campagnole-Santos (Belo Horizonte , Brazil)

Source: International Congress 2018 – Identification of therapeutic targets for asthma
Session: Identification of therapeutic targets for asthma
Session type: Thematic Poster
Number: 981
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
G. Magalhães (Belo Horizonte , Brazil), M. Rodrigues-Machado (Belo Horizonte , Brazil), J. Gregório (Belo Horizonte , Brazil), K. Gonzaga (Belo Horizonte , Brazil), P. Cassini (Belo Horizonte , Brazil), L. Barcelos (Belo Horizonte , Brazil), R. Santos (Belo Horizonte , Brazil), M. Campagnole-Santos (Belo Horizonte , Brazil). Inhaled formulation of angiotensin-(1-7) produces lung protective effects in a model of chronic asthma.. 981

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Protective effect of inhaled glucocorticosteroids on COPD model.
Source: Virtual Congress 2020 – Mechanistic insight into lung injury and repair
Year: 2020


Reducing the dose of inhaled corticosteroids (ICS) under therapy with montelukast in stable asthma: effects on lung function and inflammation
Source: Eur Respir J 2001; 18: Suppl. 33, 261s
Year: 2001

Effect of roflumilast on airway remodeling in a murine model of chronic asthma
Source: International Congress 2015 – New models for treating airway diseases
Year: 2015


Comparison of protective effect of bronchodilators in COPD
Source: International Congress 2015 – Safety of and interactions between current treatments for asthma and COPD
Year: 2015

The therapeutic efficacy of OAT-889 (dual AMCase/CHIT1 inhibitor) in comparison to montelukast in HDM-induced model of chronic airway inflammation in mice
Source: International Congress 2017 – Asthma: mechanisms and treatment
Year: 2017

Effects of low dose inhaled theophylline (ADC4022) co-administered with budesonide on inflammatory markers, lung function, and quality of life in COPD patients
Source: Annual Congress 2009 - New drugs for airways disease
Year: 2009


Effects of treatment with angiotensin-(1-7) on antigen sensitization of murine experimental model of asthma
Source: International Congress 2019 – Modelling and monitoring of airway diseases
Year: 2019

Indacaterol/glycopyrronium (IND/GLY) reduces exacerbation and improves lung function versus salmeterol/fluticasone (SFC) in patients with and without prior ICS use: The FLAME study
Source: International Congress 2016 – Pharmacological treatment of COPD: focus on LABA/LAMA combinations
Year: 2016

The impact of stepwise withdrawal of inhaled corticosteroids on lung function in COPD patients receiving dual bronchodilation: WISDOM study
Source: International Congress 2014 – New clinical evidence for asthma and COPD treatments
Year: 2014


Smoking, sputum cell counts, diffusion capacity and hyperinflation predict beneficial effects of long-term inhaled corticosteroids (ICS) on FEV1-decline in patients with mild-to-moderate COPD
Source: Annual Congress 2010 - COPD: management
Year: 2010

Additive effect of targeted lung denervation plus drug in patients with COPD
Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis
Year: 2015

The influence of inhalation device for bronchodilators on the results of therapy in primary care patients with bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD)
Source: Annual Congress 2008 - Asthma control or asthma severity
Year: 2008


The effect on mortality of adding inhaled corticosteroids to long-acting bronchodilators for COPD: A focus on the frequent exacerbator phenotype
Source: International Congress 2015 – COPD and lung function: risk factors and outcomes
Year: 2015

Pharmacological characterisation of indacaterol (QAB149), a novel once-daily inhaled β2-agonist, on small airways in human and rat lung slices
Source: Annual Congress 2006 - Novel treatments for asthma
Year: 2006


Late-breaking abstract: Inhaled calcium based dry powder inhibits rhinovirus-induced inflammation and exacerbation in a mouse model of allergic airway inflammation
Source: Annual Congress 2011 - Antimicrobial treatment and resistance in lower respiratory tract infections
Year: 2011

The effects of early intervention with inhaled budesonide on lung function in mild persistent asthma: results from the START study
Source: Eur Respir J 2003; 22: Suppl. 45, 34s
Year: 2003

LATE-BREAKING ABSTRACT: The novel inhaled dual PDE3/4 inhibitor RPL554 produces significant additional improvements in lung function when administered on top of existing standard of care in COPD patients
Source: International Congress 2016 – Late-breaking topics in airways disease
Year: 2016


Inhaled budesonide suppresses airway and systemic eosinophilic inflammation in COPD. No predictive value of a prednisolone test treatment
Source: Eur Respir J 2005; 26: Suppl. 49, 290s
Year: 2005

Effects of IL-4Rα blockade on lung inflammation and airway hyperresponsiveness using Mu317RAXMu, a murine surrogate for AMG 317, in a treatment model of cockroach allergen-induced asthma in mice
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008

The effects of oral corticosteroid treatment (OCS) on sequential lung function tests in a cohort of patients with acute hypersensitivity pneumonitis (AHP)
Source: Virtual Congress 2020 – Clinical aspects and new treatment strategies for rare interstitial lung diseases in adults and children
Year: 2020