LATE-BREAKING ABSTRACT: Aryl hydocarbon receptor and FosL1 are critical for cigarette smoke and TNF mediated activation of bronchial epithelial cells

M. F. Fleming, A. J. Jiao, F. S. Schlerman, J. S. Sypek, C. W. Williams, S. G. Goldman, K. N. Nocka (Cambridge, United States Of America)

Source: Annual Congress 2009 - Airway cell biology
Session: Airway cell biology
Session type: E-Communication Session
Number: 3344
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. F. Fleming, A. J. Jiao, F. S. Schlerman, J. S. Sypek, C. W. Williams, S. G. Goldman, K. N. Nocka (Cambridge, United States Of America). LATE-BREAKING ABSTRACT: Aryl hydocarbon receptor and FosL1 are critical for cigarette smoke and TNF mediated activation of bronchial epithelial cells. Eur Respir J 2009; 34: Suppl. 53, 3344

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cigarette smoke induce Epithelial-Derived Inflammation through activating autophagy via RAGE signaling in bronchial epithelial cells.
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Cigarette smoke modulates the PKAc-associated cross-coupling between NF-kB and glucocorticoid receptor in primary small airway epithelial cells
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013

Cigarette smoke increases TLR4 expression and modifies LPS mediated responses in airway epithelial cells
Source: Annual Congress 2007 - Epithelial networks in the airways
Year: 2007


Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia
Source: Virtual Congress 2021 – Tobacco and nicotine research during the pandemic
Year: 2021



Epidermal growth factor receptor (EGFR) overexpression in human bronchial epithelial cells amplifies IL-8 release provoked by cigarette smoke and bacterial surrogates
Source: Eur Respir J 2005; 26: Suppl. 49, 441s
Year: 2005

Cigarette smoke induces mitochondrial dysfunction via PKCd-p66Shc signaling pathway in human bronchial epithelial cells
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018

Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and the induction of inflammasome
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

Tobacco smoke induces muc5AC expression in normal bronchial epithelial cells trough activation of the NADPH system in a mechanism involving EGF-R activation
Source: Annual Congress 2009 - Translational models of lung disease
Year: 2009



Cigarette smoke-induced airway neurogenic inflammation is mediated by α,ß-unsaturated aldehydes and the TRPA1 receptor.
Source: Annual Congress 2008 - Recent advances in the pathogenesis and treatment of asthma and COPD
Year: 2008



Cigarette smoke exposure disrupts VEGF signalling through the kinase insert-domain receptor (KDR) in rat lungs
Source: Eur Respir J 2004; 24: Suppl. 48, 30s
Year: 2004

Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor
Source: Eur Respir J 2010; 36: 1143-1154
Year: 2010



Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses
Source: Eur Respir J 2005; 26: Suppl. 49, 555s
Year: 2005

RAGE blocking ameliorates cigarette smoke extract-induced human alveolar tpye II epithelial cell injury via RAGE-mediated redox sensitive DAMP signaling through Nrf2
Source: International Congress 2018 – COPD: immune regulation and therapeutic targets
Year: 2018

Cigarette smoke altered the expression of choline acetyl transferase and muscarinic receptors promoting the LTB4 release from human bronchial epithelial cells
Source: Annual Congress 2008 - Airway cell biology
Year: 2008


Cigarette smoke alters the expression of the pro-inflammatory LTB4 receptor and increases the neutrophil adhesion in bronchial epithelial cells
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

Cigarette smoke extracts decrease basal and lipopolysaccharide-induced expression of macrophage receptor with collagenous structure via degradation of p300
Source: International Congress 2018 – Disease exacerbations from a molecular point of view
Year: 2018



Cigarette smoke extract, affecting choline acetyltransferase and muscarinic receptor M3 expression, induces MUC5AC in NCI-H292 cell line
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


Carbocysteine restores the expression and the activation of TLR4 altered by cigarette smoke extracts in bronchial epithelial cells
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

Role of aberrant Wnt signaling in the lung epithelial response to cigarette smoke in COPD
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011

Cigarette smoke extract (CSE) promotes acetylcholine (ACh) mediated inflammation and oxidative stress by PEBP1/Raf-mediated MEK and ERK pathway in human bronchial epithelial cells
Source: International Congress 2015 – New data on established treatments for asthma and COPD
Year: 2015