Source: Annual Congress 2009 - Epidemiology and management of lung cancer
Disease area: Thoracic oncology

Abstract

To determine the incidence of lung cancer in patients undergoing bronchoscopy, we performed a retrospective analysis of procedures done in the Endoscopy/Bronchoscopy unit in a Dublin teaching hospital from 2004 to 2008.
A total of 50,144 procedures were carried out in the unit. This included 3,661 bronchoscopies, of which 967(26%) yielded the diagnosis of lung cancer. Of these, endobronchial lesions were seen in 588, whereas 379 cases showed lung cancer that was not visible endobronchially, usually requiring TBBx or TBNA (+/-EBUS) for diagnosis. A further 38 endobronchial lesions were non-cancerous. Histology showed Non-Small Cell Carcinoma 72% (Squamous cell 31.5%, Adenocarcinoma 30%, undifferentiated 10.5%) Small Cell Carcinoma 19% and Others 9%. Squamous cell was the most common endobronchial tumour observed, whereas Adenocarcinoma was the most common among peripheral lesions, as expected. The majority of endobronchial tumours were located in the upper lobes. 86% of patients had a smoking history and adenocarcinoma was the most frequent cancer in non smokers at 40%. Male: Female ratio was 3:2. 61% occurred between the ages of 61-80. In 84% of cases the indication for bronchoscopy was a mass noted on imaging. 1.5% cases the presented with haemoptysis alone. 10% of patients had minor complications, including bleeding and O2 desaturation which were easily controlled. Serious Complications were extremely rare including 1 death (<0.03%) and 2 Cardio respiratory arrests (<0.05%). The incidence of pneumothorax post transbronchial biopsy was < 1%.
Electronic database provides a useful tool for audit of clinical practice. 1 in 4 patients undergoing Bronchoscopy in this major teaching hospital in Dublin has Lung Cancer.

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Citations should be made in the following way:
S. Shahbaz, U. Nic Ionmhain, F. O‘Connell (Dublin, Ireland). 4 year lung cancer audit in a Dublin teaching hospital. Eur Respir J 2009; 34: Suppl. 53, 4677

Member's Comments

KHAN Kashif - 15.09.2009 16:18
4 year lung cancer audit in a dublin teaching hospital
Again, How many Benign proved to be Malignant? Was the Gender distribution similar for Adeno Ca below 50yrs...?just co-incidence?

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