Socioeconomic deprivation as a poor prognostic factor in small cell lung cancer (SCLC)
G. Hardavella, E. Nasaina, P. Galanis, E. Arkoumani, Y. Dalavanga, D. Stefanou, S. Constantopoulos, A. Maina (Athens, Ioannina, Strasbourg, Greece)
Source: Annual Congress 2009 - Epidemiology and management of lung cancer
Session: Epidemiology and management of lung cancer
Session type: E-Communication Session
Number: 4679
Disease area: Thoracic oncology
Abstract Introduction: Social deprivation is correlated with an increased incidence of many neoplasms, but the situation in SCLC hasn‘t been thoroughly studied.Aim: To investigate the association between socioeconomic status, clinical outcome and 5-year survival in SCLC patients.Materials and methods: Fifty SCLC patients (diagnosed in 01/2003-02/2004) were rectospectively reviewed regarding their epidemiological data, socioeconomic characteristics, residence area, marital status, treatment, health care access, stage and 5-year survival.Results: Our study included 45 males and 5 females (mean age 64.3 years). The presence of metastasis wasn‘t associated with any epidemiological or socioeconomic data (p>0.05). The stage at diagnosis wasn‘t significantly associated with epidemiological data (age p=0.76, gender p=0.2) but was associated with the residence area (p=0,025), the educational level (p=0.002) and health care access (p=0.02). Stage was independent of marital status(p=0.5) and profession (p=0,3). Five-year survival was only correlated with chemotherapy (OR=0.87, 95% CΙ = 0.6-1.1, p<0.001) and not with any other epidemiological or socioeconomic factor.Conclusions: The socioeconomic pattern of SCLC at time of diagnosis is partially correlated with health care access and patient outcome, thus compounding the increased invasiveness of this histological type of the disease. Five-year survival follows a different behavioral pattern by being independent from socioeconomic factors probably due to the simultaneous implication of standardized treatment regimens in SCLC.
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G. Hardavella, E. Nasaina, P. Galanis, E. Arkoumani, Y. Dalavanga, D. Stefanou, S. Constantopoulos, A. Maina (Athens, Ioannina, Strasbourg, Greece). Socioeconomic deprivation as a poor prognostic factor in small cell lung cancer (SCLC). Eur Respir J 2009; 34: Suppl. 53, 4679
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