Source: Annual Congress 2009 - Prognosis and comorbidities in COPD
Disease area: Airway diseases

Abstract

Nutritional status disorders more frequent concernes COPD patients with predominance of emphysema than chronic bronchitis. Aim of study was to check the dependence between nutritional status and degree of emhysematous damage of lungs, exercise tolerance and prognosis.
Group of 61 (60,66% males and 39,34% females) COPD patients in different stages of the disease (I°- 6,56%; II °- 31,15%; III° - 36,06%; IV°-26,23%) took a part in the study. Nutritional status: BW-body weight, BMI-body mass index, FFMI-fat free mass index, MMI-muscle mass index (Akern BIA 101) as well asspirometry and bodypletysmografy (Master Screen Body, Jaeger ) with assessment of FEV1-volume expired in 1st second, ITGV- intrathoracic gas volume, RV- residual volume, and diffusing capacity-DLCO; MMRC dyspnea scale; gasometry (pO2, pCO2, O2 sat.); 6MWD-six minut walking distanse; BODE was performed in examined patients.
Parameters of nutritional status: BM, BMI, FFMI, MMI correlated with stage of the disease [R Spearman (RS) 0,25; 0,32; 0,21; 0, 30 respectively]. It was observed inversely dependence between each nutritional status parameters: BM, BMI, FFMI, MMI and ITGV (RS -0,45; -0,44; -0,39; -0,38 respectively). In the case of RV inversely correlation was found only for BMI (RS -0,38). BM, BMI, FFMI, MMI correlated with DLCO (RS 0,56; 0,49; 0,37; 0,38 respectively) and inversely proportional with BODE (RS -0,38; -0,37; -0,54; -0,42 respectively), but not with gasometric parameters, 6MWD and MMRC.
Worsening of nutritional status has a dependence with increase of emphysema degree in COPD patients, especially with diffusing disorders capacity as well as poor prognosis.

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Citations should be made in the following way:
B. Kuznar-Kaminska, H. Batura-Gabryel, B. Brajer, J. Kaminski (Poznan, Poland). Assessment of the dependence between nutritional status and functional damage of lungs in COPD patients. Eur Respir J 2009; 34: Suppl. 53, 514

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