Source: Annual Congress 2009 - Treatment of lung cancer

Abstract

Introduction
Radical pulmonary resection is a treatment of choice in early non-small cell lung cancer (NSCLC). In contrary extended surgery (pneumonectomy) may significantly impair patients‘ activity and deteriorate quality of life (QOL).
Aim of the study
The aim of the study was to determine the influence of surgical treatment of NSCLC on lung function and QOL.
Patients and methods
29 patients in the mean age of 65 years (51-79 years) who underwent pneumonectomy because of NSCLC in the Department of Thoracic Surgery in Gdansk were included into the study. Control group was consisted of 35 patients with less extended treatment (lobectomy – 34, segmentectomy – 1) in the mean age of 65 (46-80 years) . In all patients both static and dynamic spirometry, DLCO and oxygen saturation (O2 SAT) measurements were performed. Furthermore patients were asked to complete St George Respiratory Questionnaire (SGRQ). Dyspnea level was assessed with Borg scale and Visual Analoge Scale (VAS) and physical efficiency with 6-minute walking distance test (6-MWT).
Results
The mean SGRQ results were 46,7 in pneumonectomy group and 40,8 in control group; (p<0,2). Similarly no differences were found for particular parts of SCRQ and for perception of dyspnea assessed by VAS and Borg scale. There were no significant differences between the groups in FEV1, DLCO and O2 SAT (p<0,5). Physical efficiency assessed with 6 MWT was also similar in both groups (p<0,4).
Conclusion
Type of surgical treatment of NSCLC does not affect general health status, dyspnea, physical efficiency or every-day life. This findings should be confirmed in larger series, since they might potentially influence treatment decisions.

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B. Wajda, K. Kuziemski, K. Specjalski, K. Lewandowska, L. Górska, W. Rzyman, E. Jassem (Gdansk, Poland). Lung function and quality of life after surgical treatment of non-small cell lung cancer – preliminary results. Eur Respir J 2009; 34: Suppl. 53, 2656

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