Source: Annual Congress 2009 - Pulmonary rehabilitation: extending the scope and benefit of rehabilitation for patients with chronic respiratory disease
Disease area: Airway diseases

Abstract

Background: Exercise may promote bronchial secretions cleaning, preventing air-trapping and improving ventilation/perfusion imbalance. Information about functional and arterial blood gases (ABG) changes after a rehabilitation program (RP) in patients with bronchiectasis is scant in the literature.
Objectives: To study changes in lung function and ABG in patients with stable bronchiectasis submitted to RP, as well as influences of gender, degree of obstruction, P aeruginosa colonization or exacerbations.
Methods: Retrospective evaluation of 18 patients with bronchiectasis who attended a RP (mean 11 weeks doing stationary cycling for 30 min 3 times a week at a load 30-60% of the maximum work rate (MWR) evaluated by cardiopulmonary exercise testing (CPET), upper limbs and quadricipetes training) and had functional (FVC, FEV1, FEV1/FVC, RV, MIP, MEP) and ABG evaluation at the start and end of the program.
Results: Seven males and 11 females with ages ranging from 21 to 74 (median 50 yrs). Thirteen patients were severely obstructed and 5 were colonized with P aeruginosa. Significant increases were found in FVC, FEV1 and FEV1% (p values 0.023, 0.021, 0.031 respectively), and decreases in RV and RV% (p value 0.011 for both) in this group as a whole. Patients with lower charges (≤ 50% MWR) showed larger increase in FEV1 (p=0.046). More significant improvement in FVC, FVC% and RV was seen in patients colonized with P aeruginosa. FEV1/FVC, MIP, MEP or ABG values did not show significant changes. Gender, exacerbations during RP or need of antibiotics did not influence the results.
Conclusions: RP seems to change lung function parameters in a favorable way in patients with bronchiectasis.

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Citations should be made in the following way:
P. Mota, A. P. Vaz, P. Viana, P. Martins, E. Araujo, I. Gomes (Porto, Portugal). Functional and arterial blood gases changes after a rehabilitation programme in patients with bronchiectasis. Eur Respir J 2009; 34: Suppl. 53, 539

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