Studies into the mechanisms of deficient type I interferon production in asthmatic bronchial epithelial cells

M. Leino, L. Uller, B. Green, P. H. Howarth, S. T. Holgate, D. E. Davies (Southampton, United Kingdom; Lund, Sweden)

Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma
Session: Novel mechanisms in the pathogenesis of asthma
Session type: Thematic Poster Session
Number: 889
Disease area: Airway diseases, Respiratory infections

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Leino, L. Uller, B. Green, P. H. Howarth, S. T. Holgate, D. E. Davies (Southampton, United Kingdom; Lund, Sweden). Studies into the mechanisms of deficient type I interferon production in asthmatic bronchial epithelial cells. Eur Respir J 2009; 34: Suppl. 53, 889

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IL-4 modulation of rhinovirus-induced CCL20/MIP-3a production in bronchial epithelial cells
Source: Annual Congress 2009 - Viruses and respiratory infections: prevalence and mechanisms of infection
Year: 2009


Investigating the effects of interleukin-33 on rhinovirus A induced changes in asthmatic bronchial epithelial cells
Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes
Year: 2020


Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells
Source: Eur Respir J 2012; 39: 439-445
Year: 2012



Production of collagen I mRNA by bronchial epithelial cell lines and absence of modulation by Th2 cytokines
Source: Eur Respir J 2004; 24: Suppl. 48, 98s
Year: 2004

Establishing the effects of chronic exposure to IL-9 alone and in combination with IL-13 on the differentiation of asthmatic and non-asthmatic paediatric bronchial epithelial cells
Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma
Year: 2009

Effect of s-carboxymethylcysteine on mucin production in airway epithelial cells in vitro
Source: Eur Respir J 2005; 26: Suppl. 49, 97s
Year: 2005

LSC Abstract – Defect in the translational control of cytokines leading to hyperresponsive bronchial epithelial cells in asthmatics
Source: International Congress 2016 – Molecular immunology of the lung
Year: 2016



IL-8 and TSLP production as markers of bronchial epithelial cell activation in IL-17A mediated airway inflammation in COPD: Role of tiotropium
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013

Small molecular inhibition of TSLP production in primary asthmatic bronchial epithelial cells
Source: Annual Congress 2010 - Immune modulation of airways diseases
Year: 2010

Dual effect of neutrophils on secretory component production by human bronchial epithelial cells
Source: Eur Respir Rev 2006; 15: 175-176
Year: 2006



IL-25 secreted from epithelial cells has the potential to promote airway remodeling in asthma
Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms
Year: 2012

Bronchial epithelial cells from COPD patients overproduce an upstream Th2 regulator cytokine in response to viral stimuli
Source: Annual Congress 2009 - Pathology and immunology of COPD
Year: 2009

Enhanced inflammatory response to formaldehyde in human bronchial epithelial cells
Source: Annual Congress 2011 - Environmental exposure and disease mechanisms
Year: 2011

Regulation of secretory component production in human bronchial epithelial cells by TGF-β
Source: Annual Congress 2008 - Airway cell biology
Year: 2008


CD40 ligation modulates inflammatory cytokines production by human bronchial epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 246s
Year: 2001

Effect of interleukin-8 on human bronchial epithelial cell responses
Source: Eur Respir J 2006; 28: Suppl. 50, 431s
Year: 2006

Upregulation of the production of TGF-β and IL-4 and downregulation of IL-6 by apoptotic human bronchial epithelial cells: possible role in regulation of epithelial repair following acute lung injury
Source: Eur Respir J 2001; 18: Suppl. 33, 477s
Year: 2001

Ozone induced bronchial epithelial cytokine expression differs between asthmatic and healthy subjects
Source: Eur Respir J 2002; 20: Suppl. 38, 22s
Year: 2002

Role of TGF-b1 in type I collagen production in bronchial epithelial cells: effects on Smad7 inhibitory role?
Source: Annual Congress 2008 - Animal models of pulmonary fibrosis: mechanisms and therapies
Year: 2008