Source: Annual Congress 2009 - Cystic fibrosis: advances in clinical research
Disease area: Airway diseases

Abstract

Numerous studies have reported patients with chronic illness have more risk for depression and anxiety, with serious consequences for health outcomes. Objectives: To assess the prevalence of symptoms of depression and anxiety in a sample of patients with cystic fibrosis (CF), atypical cystic fibrosis (ACF) and bronchiectasis non-cystic fibrosis (BCNCF), controlled in an Adult CF Unit, and its relation on the clinical characteristics. Methods: Cross sectional study. Administration of the Center of Epidemiological Studies Depression Scale (CES-D) and the Hospital Anxiety and Depression Scale (HADS) to patients in a clinical and functional stability in their annual medical examination. Results: 91 adults completed the scales (CF: 46%; ACF: 21%; BC NCF: 33%). Significant differences were found on the age (CF: 25,19; ACF: 37,84; BCNCF: 37,35). 35% of the patients had depression according to the CES-D (CF: 33%; ACF: 26%; BCNFQ: 43%)(NS) and 6,6% according to the HADS (CF: 4,8%; ACF: 10,5%; BCNFQ: 6,7%)(NS). The HADS score classified 22% of the patients with anxiety (NS). 80% of the individuals had bacterial colonization. CF group had significantly lower Bhalla score, FEV1% and anthropometric parameters (weight, body-mass index, skinfolds and upper arm circumference), higher rate of bacterial colonizations and severe exacerbations (p<0,001). Conclusions: The presence of depression (assessed by CESD) and anxiety (HADS) were high in the three groups and similar than other results reported previously in adults with CF, despite having different clinical characteristics. The proportion of patients with a positive screening for depression assessed by CESD was higher than the one assessed by HADS.

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I. Gaspar-Garcia, C. Olveira-Fuster, F. Espildora-Hernandez, G. Olveira-Fuster, A. Dorado-Galindo, A. Padilla-Galo, J. J. Cebrian-Gallardo, J. L. De la Cruz-Rios (Marbella, Malaga, Spain). Depression and anxiety in patients with cystic fibrosis and non-cystic fibrosis bronchiectasis. Eur Respir J 2009; 34: Suppl. 53, 1255

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