Is living close to main roads a risk for OSAS?
M. Gerbase, D. Felber Dietrich, J. Dratva, S. Liu, J. M. Gaspoz, B. Jean-Claude, C. Schindler, F. Roche, T. Rochat (Geneva, Basle, Switzerland; St. Etienne, France)
Source: Annual Congress 2009 - Socio-economic and epidemiological aspects of sleep apnoea
Session: Socio-economic and epidemiological aspects of sleep apnoea
Session type: Thematic Poster Session
Number: 3669
Disease area: Sleep and breathing disorders
Abstract Background: Noise-induced sleep fragmentation has been reported to increase upper airway collapsibility. Sleep breathing disorders are associated with hypoxemia and nocturnal arrhythmias. Decreased nocturnal heart rate variability (HRV) has been reported in sleep-related breathing disorders such as OSAS (obstructive sleep apnea/hypopnea syndrome). We investigated the association of traffic-related noise exposure during sleep and HRV. Methods: 1151 participants of the SAPALDIA cohort (≥ 50yrs old) answered to a health questionnaire and underwent a 24-hour ECG holter. The heart rate variability (HRV) frequency-domain component of the 24-hour ECG was monitored, and the percentage of the very low frequency increment interval over the total power spectral density was used to define OSAS (%VLFI ≥ 4%). Distance of individuals‘ address within 100 meters from a highway or class 1 road defined by the VECTOR25© swisstopo classification was used to define traffic noise. Logistic regression models included age, sex, body mass index and smoking status. Results: Mean±SD %VLFI was 5.1±3.1 (range, 0.08-21.3). Higher %VLFI was found in subjects reporting being disturbed by traffic noise at home than subjects not disturbed by noise (5.2±3.1 vs. 4.8±2.9, p=0.05). Male gender and proximity of home to main roads were significant predictors of increased %VLFI (p=0.01 and p=0.03, respectively). After adjusting for relevant covariates, a significant association was found between the distance of subjects‘ home address inferior to 100m and the %VLFI (OR: 1.36; 95% CI 1.04-1.79; p=0.026). Conclusion: Living nearby a major road is positively associated with sleep-related ECG disturbances suggestive of OSAS.
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M. Gerbase, D. Felber Dietrich, J. Dratva, S. Liu, J. M. Gaspoz, B. Jean-Claude, C. Schindler, F. Roche, T. Rochat (Geneva, Basle, Switzerland; St. Etienne, France). Is living close to main roads a risk for OSAS?. Eur Respir J 2009; 34: Suppl. 53, 3669
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