Designed core-shell nanoparticles: intracellular localization and pro-inflammatory cytokine release in lung cells

A. D. Lehmann, W. Parak, F. Zhang, A. Zulqurnain, P. Gehr, B. Rothen-Rutishauser (Bern, Switzerland; Marburg, Germany)

Source: Annual Congress 2009 - Lung cell biology and immunology
Session: Lung cell biology and immunology
Session type: Oral Presentation
Number: 4669
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. D. Lehmann, W. Parak, F. Zhang, A. Zulqurnain, P. Gehr, B. Rothen-Rutishauser (Bern, Switzerland; Marburg, Germany). Designed core-shell nanoparticles: intracellular localization and pro-inflammatory cytokine release in lung cells. Eur Respir J 2009; 34: Suppl. 53, 4669

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effects of functionalised chalcones on pro-inflammatory mediator release from lung epithelial cells
Source: Annual Congress 2009 - Inflammatory cells and cytokines
Year: 2009


Titanium dioxide nanoparticles induce IL-8 expression in lung epithelial cells by a MAPK-dependent mechanism
Source: Annual Congress 2007 - Acute and chronic effects of air pollution
Year: 2007


Histamine-stimulated monocytes release microparticles that upregulate IL-8 synthesis by human alveolar epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 228s
Year: 2006

Pro-inflammatory effects of exposure of the combination of silicon- and iron-containing particles upon human lung fibroblasts
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019


Respirable particles and IL-4 have an additive effect on the release of IL-8 from primary bronchial epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 484s
Year: 2002

Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung
Source: Eur Respir J 2006; 28: 275-285
Year: 2006



Late-breaking abstract: Activation of the macrophage inflammasome by TLR3 ligation potentiates release of IL-8 and IP-10 from alveolar type II epithelial cells via a paracrine cytokine network
Source: Annual Congress 2011 - Epithelial cells: role in health and disease
Year: 2011

The antifibrotic effect of Imatinib loaded CD44 targeted gold nanoparticles (Im-CD44-GNP) relies on alveolar macrophage regulation
Source: International Congress 2018 – CTD-ILD and hypersensitivity pneumonitis: from the bench to the bedside
Year: 2018




Eosinophil cationic protein stimulates TGF-β1 release by human lung fibroblasts
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Role of p53 in murine macrophages and alveolar epithelial cells response to nanoparticles
Source: Annual Congress 2011 - Environmental exposure and disease mechanisms
Year: 2011


Mast cell tryptase induce alarmin release and secretion of pro-inflammatory cytokines from bronchial epithelial cells
Source: International Congress 2018 – Understanding the immunopathology that underlies airway obstructive diseases
Year: 2018



Nebulised lipid–polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells
Source: ERJ Open Res, 5 (2) 00161-2018; 10.1183/23120541.00161-2018
Year: 2019



TLR-4 downregulation in COPD impairs cytokine release from monocytes and Th1-lymphocytes in response to bacterial endotoxin
Source: Annual Congress 2009 - What is new in molecular pathology and functional genomics of neoplastic and non-neoplastic lung disease?
Year: 2009


Organic dust induces intracellular production of cytokines in monocytes, NK and T cells in vitro
Source: Eur Respir J 2001; 18: Suppl. 33, 113s
Year: 2001

Involvement of nitric oxide, proinflammatory cytokines and effector cells in the inflammatory process in COPD patients
Source: Eur Respir J 2005; 26: Suppl. 49, 54s
Year: 2005

The cationic protein poly-L-arginine brings about a hyperresponsive interleukin(IL)-6 and a hyporesponsive IL-8 production in airway epithelial-like cells
Source: Eur Respir J 2001; 18: Suppl. 33, 246s
Year: 2001

Protein S inhibits the secretion of inflammatory cytokines from alveolar epithelial cells
Source: Annual Congress 2008 - Structural remodelling in COPD
Year: 2008

Imaging of the interaction of fine particles and nanoparticles with lung cells
Source: Annual Congress 2009 - WS1 - New imaging methods for the researcher: believe what you see!
Year: 2009



The maturation of dendritic cells mediated by a polyvalent mechanical bacterial lysate (PBML) results in the secretion of cytokines inducing an anti-bacterial polarization of the locoregional immune-response
Source: Eur Respir J 2004; 24: Suppl. 48, 357s
Year: 2004