Survival of elderly patients with non-small lung cancer tretaed with combined chemotherapy and radiotherapy

D. Sazdanic-Velikic, N. Secen, D. Bursac, A. Tepavac, G. Popovic, B. Perin, M. Antonic (Sremska Kamenica, Republic Of Serbia)

Source: Annual Congress 2009 - Treatment of lung cancer
Session: Treatment of lung cancer
Session type: Thematic Poster Session
Number: 2648
Disease area: Thoracic oncology

Congress or journal article abstract

Abstract

INTRODUCTION: Combined chemotherapy and radiotherapy is an appropriate treatment for elderly NSCLC patients with good performance status (ECOG 0-1).
PATIENTS AND METHODS: We analyzed 25 lung cancer patients who were older then 65 years of age with locally advanced NSCLC diagnosed in Institute for Lung Disease of Vojvodina in Sremska Kamenica in 2000-2005. Patients received chemotherapy regimen with cisplatin 60mg/m2(day 1) and etoposide 100mg/m2 (day 1,2,3) in four weeks cycles combined with sequential radiotherapy (spleet-course 40Gy).
RESULTS: In these group of patient median survival were 16.28 months, median time to progression were 14.37 months. We acchived 1-year survival in 68% of patients (17 patients) and 2-year survival in 12% of patients(3 patients) , 3-year survival in 4% of patients(1 patients).
CONCLUSION: Advanced age alone should not preclude combined treatment for NSCLC. In fit elderly with advanced NSCLC combined chemotherapy and radiotherapy is tolerable treatment.


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D. Sazdanic-Velikic, N. Secen, D. Bursac, A. Tepavac, G. Popovic, B. Perin, M. Antonic (Sremska Kamenica, Republic Of Serbia). Survival of elderly patients with non-small lung cancer tretaed with combined chemotherapy and radiotherapy. Eur Respir J 2009; 34: Suppl. 53, 2648

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