Source: Annual Congress 2009 - Treatment of lung cancer
Disease area: Thoracic oncology

Abstract

Introduction
Prognostic importance of estrogen receptor(ER) in some group of neoplastic diseases like breast and endometrium carcinoma is determined previously. ER(+) tumour give responses to hormonal therapy and show better prognosis. In our study, we investigated whether estrogen receptor has prognostic value on operated Non-Small Cell Lung Cancer (NSCLC) or not.
Material and Method
We investigated 108 NSCLC patients on whom lobectomy or pnomectomy has been performed between January 2002 and December 2004.
63 of them were squamous cell carinoma, 33 of them were adenocarcinoma, 5 of them were NSCLC(untyped), 4 of them were large cell carcinoma and 3 of the were adenosquamous. There were not estrogen receptor detected on any subjects.
Parafin tissue blocks were taken from pathology laboratory. Confirmation of diagnosis has been checked by reviewing all Histopathological samples . It has been evaluated by painting with antiestrogen receptor (RTU - ER - 6F 11).
Resulsts
Estrogen receptor positivity did not revealed in any patients.
Conclusion
Our findings suggested that estrogen receptor is not expressed on NSCLC patients.

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Citations should be made in the following way:
S. Kahraman, F. Kadakal, A. Uysal, G. Aras, V. Yilmaz (Istanbul, Turkey). Prognostic value of the oestrogen receptor in operated NSCLC. Eur Respir J 2009; 34: Suppl. 53, 2640

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