MMP-12 activates protease activated receptor (PAR)-1, upregulates placenta growth factor and leads to pulmonary emphysema Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium Year: 2018
Effect of proteinase inhibitor from crataeva tapia (cratabl) in distal lung mechanical, inflammatory and remodeling alterations induced by elastase in mice Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury Year: 2011
Treatment with proteinase inhibitor, BbCI, modulates inflammatory response, mechanic alterations, and remodeling on elastase-induced emphysema in mice Source: Annual Congress 2012 - The many roads to lung injury Year: 2012
17β-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor Source: Annual Congress 2010 - Epithelial cells: cell biology and role in lung disease Year: 2010
Statins inhibit human lung fibroblast production and activation of MMPs Source: Eur Respir J 2007; 30: Suppl. 51, 692s Year: 2007
Evidence that cathepsin G counteracts the profibrotic effects of neutrophil elastase following lung injury Source: Eur Respir J 2001; 18: Suppl. 33, 181s Year: 2001
Plant proteinase inhibitor from crataeva tapia (CrataBl) attenuates inflammation and remodelling induced by elastase in mice Source: Annual Congress 2013 –Novel mechanisms in lung injury Year: 2013
A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice Source: Eur Respir J 2012; 40: 1475-1482 Year: 2012
SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition Source: Eur Respir J 2011; 37: 1083-1090 Year: 2011
PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity Source: ERS Lung Science Conference 2021 Year: 2021
Inflammation and remodeling modulated by anti IL17 in model of lung injury induced by elastase in mice Source: International Congress 2019 – Involvement of the environment and inflammation in pulmonary remodelling Year: 2019
Roflumilast potently inhibits CXCL1 mediated neutrophil migration in COPD patients Source: Annual Congress 2011 - COPD: clinical studies and animal cell models Year: 2011
Attenuation of bleomycin-induced pulmonary fibrosis by direct thrombin inhibition is accompanied by a reduction in connective tissue growth factor mRNA levels Source: Eur Respir J 2001; 18: Suppl. 33, 199s Year: 2001
Statins suppress LPS-induced proinflammatory cytokine production from human bronchial epithelial cells Source: Annual Congress 2009 - Epithelial cell biology Year: 2009
A decoy CXCL8 with increased glycosaminoglycan binding has potent anti-inflammatory activity in lung inflammation models Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
Hsp90 binding inhibitors improve survival in a murine model of sepsis induced acute lung injury Source: Annual Congress 2006 - Novel pathogenic aspects of acute lung injury and acute respiratory distress syndrome (ARDS) Year: 2006
Dimethylfumarate reduces growth factor- and cytokine-induced IL-6 release from human lung fibroblasts: role of (NF)-κB Source: Annual Congress 2008 - Airway cell biology and immunology Year: 2008
Plant proteinase from bauhinia bauhinioides kallikrein inhibitor (BbKI) attenuates inflammation and remodelling induced by elastase in mice Source: Annual Congress 2013 –Novel mechanisms in lung injury Year: 2013
Aerobic training inhibits leukocytes production of oxidants, pro-inflammatory and pro-fibrotic factors reducing asthmatic phenotype Source: Annual Congress 2012 - Cell culture and animal models of lung disease Year: 2012