NADPH oxidases are regulated in a mouse model of tobacco smoke induced COPD

M. Seimetz, N. Parajuli, M. Roth, R. Schermuly, A. Ghofrani, W. Seeger, F. Grimminger, N. Weissmann (Giessen, Germany)

Source: Annual Congress 2009 - Hot topics in molecular pathology and functional genomics of COPD
Session: Hot topics in molecular pathology and functional genomics of COPD
Session type: Oral Presentation
Number: 2790
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Seimetz, N. Parajuli, M. Roth, R. Schermuly, A. Ghofrani, W. Seeger, F. Grimminger, N. Weissmann (Giessen, Germany). NADPH oxidases are regulated in a mouse model of tobacco smoke induced COPD. Eur Respir J 2009; 34: Suppl. 53, 2790

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Regulation of glutaredoxins by cigarette smoke
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009

Acute cigarette smoke induced airway neutrophilia in a mouse model is ROS dependent
Source: Annual Congress 2008 - Inflammatory trigger mechanisms in asthma and COPD
Year: 2008


Mitochondria are essential in cigarette smoke induced ROS generation
Source: Annual Congress 2008 - Airway cell biology
Year: 2008


Reversible inhibition of mitochondrial complex IV activity in PBMC following acute smoking
Source: Eur Respir J 2004; 23: 214-218
Year: 2004



Cigarette smoke in mice, rats and guinea-pigs: value to the study of pathogenic factors involved in COPD
Source: Annual Congress 2005 - PG11 - Experimental models for COPD and asthma
Year: 2005

Mitochondrial dehydrogenase activity as a measure of tobacco smoke toxicity
Source: Annual Congress 2007 - The versatile aspects of nicotine addiction
Year: 2007


Expression of superoxide dismutases in cigarette smoke induced bronchitis is modulated by ambroxol
Source: Eur Respir J 2003; 22: Suppl. 45, 79s
Year: 2003

Eucalyptol reduced inflammation and oxidative stress on mouse lungs exposed to long and short-term cigarette smoke
Source: International Congress 2015 – Inflammation and remodelling in lung disease
Year: 2015

COPD fibroblasts are more responsive to cigarette smoke exposure
Source: Annual Congress 2009 - Mechanisms of pulmonary inflammation and fibrosis
Year: 2009

A comparison of anti-inflammatory compounds in a steroid-insensitive mouse tobacco smoke model
Source: Annual Congress 2012 - New drug targets and pre-clinical models for respiratory diseases
Year: 2012


Reduced airway expression of cytoprotective CC10 in COPD patients and mice exposed to cigarette smoke
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

Role of highly reactive aldehydes in cigarette smoke induced airway inflammation
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011


Inhibition of β-adrenoceptors alleviated mucus secretion and emphysema in cigarette smoke exposed rat model
Source: Annual Congress 2011 - Recent developments in COPD
Year: 2011

Alveolar changes in a chronic tobacco smoke inhalation COPD mouse model
Source: Annual Congress 2008 - The biology of smoking and COPD
Year: 2008

PDE4 inhibition prevents corticosteroid-resistant lung inflammation induced by cigarette smoke exposure in mice
Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury
Year: 2009


Blocking IL-20 pathway limits the development of bacteria induced exacerbation in mice chronically exposed to cigarette smoke.
Source: International Congress 2018 – Disease exacerbations from a molecular point of view
Year: 2018




Regulation of immunoproteasomes by cigarette smoke
Source: Annual Congress 2012 - Basic and translational studies in COPD
Year: 2012

Cigarette smoke exposure in mice leads to a loss of reversible cysteine oxidations PSSG and PSNO in lung
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011

Cigarette smoke disrupts mitochondrial function by acute blockage of the respiratory chain
Source: Annual Congress 2005 - Cellular and molecular approaches to lung injury research
Year: 2005


The interaction of cigarette smoke and allergens in a mouse model of asthma
Source: Eur Respir J 2007; 30: Suppl. 51, 736s
Year: 2007