Source: Annual Congress 2009 - Inspiratory muscle training and assessment and breathing retraining
Disease area: Airway diseases



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Citations should be made in the following way:
R. Gosselink, J. De Vos, S. van den Heuvel, G. Kwakkel (Leuven, Belgium; Amersfoort, Amsterdam, Netherlands). Effects of inspiratory muscle training in patients with COPD: a comprehensive and updated meta-analysis. Eur Respir J 2009; 34: Suppl. 53, 4292

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LAWSON Rod - 15.09.2009 15:34
6MWT, minimum important difference and statistically significant difference, etc.
Actually the mean improvement to 6MWT appears to be 32m which is below the minimal important difference, i.e. the metanalysis including 22 studies using this shows a statistically signficant but clinically insigniricant improvement in 6 mwd. Likwise the improvement in inspiratory musclce strength is tiny though statistically signficant. The imrpovement in CRQ approaches but doesn't reach minimum important difference, though statistically significant. The conclusions of the study appear a bit shakey therefore; it would be more correct to say that there were detectable but insignificant improvements to these things. I guess the important point is that where improvements were seen they were in folk with detectable weakness to start with, so to me the take home message would have to be; a) Not a treatment for all b) Possibly of value for targeted group c) More research needed (well I never!!!) ps I note the overall BMI was very normal, looks like perhaps 20% overall had low BMI. I would have thought in general this might be an easy group to target; those with wasted/abnormal muscles might perhaps be expected to benefit most, those who have maintained muscle mass perhaps won't get much benefit. After all we do use our resp muscles 24 hours per day so they're not entirely untrained........

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