Chymase-positive mast cells are related to the vascular remodelling in asthma

A. Zanini, A. Chetta, A. Tipa, A. Castagnaro, R. D‘Ippolito, M. Neri, D. Olivieri (Tradate, Parma, Italy)

Source: Annual Congress 2006 - Cellular biology of asthma and COPD
Session: Cellular biology of asthma and COPD
Session type: Poster Discussion
Number: 3168
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Zanini, A. Chetta, A. Tipa, A. Castagnaro, R. D‘Ippolito, M. Neri, D. Olivieri (Tradate, Parma, Italy). Chymase-positive mast cells are related to the vascular remodelling in asthma. Eur Respir J 2006; 28: Suppl. 50, 3168

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Increased numbers of alveolar mast cells with an altered phenotype are linked to peripheral airway remodelling in patients with allergic asthma
Source: Annual Congress 2012 - Mechanisms of asthma
Year: 2012

In vivo allergen-activated inflammatory eosinophils reduced airway smooth muscle cells apoptosis in allergic asthma patients
Source: Virtual Congress 2021 – New insights into the airway immunology of lung disease
Year: 2021


Distribution and degranulation of airway mast cells in normal and asthmatic subjects
Source: Eur Respir J 2002; 19: 879-885
Year: 2002



Role of mast cells and chymase in pulmonary vascular remodeling
Source: Annual Congress 2011 - Clinical characteristics of patients with pulmonary hypertension
Year: 2011

The role of mast cells in allergic inflammation: mast cells' interactions with their microenvironment
Source: Annual Congress 2009 - Mast cells reborn: beyond the allergic response
Year: 2009

IL-25 secreted from epithelial cells has the potential to promote airway remodeling in asthma
Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms
Year: 2012

Mast cells as key participants in inflammation and remodelling in the respiratory tract
Source: Annual Congress 2006 - Mast cells and basophils as key effector cells in airway inflammation and remodelling
Year: 2006


Mast cells and eosinophils: the two key effector cells in allergic inflammation
Source: Annual Congress 2010 - Mast cells and eosinophils: the two key effector cells in allergic inflammation
Year: 2010

Decreased degranulating and mast cells in the small airway wall of COPD patients is indicative of dysfunctional immunity.
Source: International Congress 2017 – Translational studies of lung disease
Year: 2017

Infiltration of mast cells with increased IgE-receptor expression in peripheral lung of patients with uncontrolled asthma
Source: Annual Congress 2010 - Asthma: basic science and clinical studies
Year: 2010

Airway epithelial cells, eosinophils and myofibroblasts express connective tissue growth factor (CTGF) in inflamed asthmatic airway
Source: Eur Respir J 2001; 18: Suppl. 33, 19s
Year: 2001

Increased arginase activity contributes to airway remodelling in chronic allergic asthma
Source: Eur Respir J 2011; 38: 318-328
Year: 2011



Allergen-pulsed bone marrow-derived dendritic cells abolish the influx of allergic inflammatory cells in mouse asthma model
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010

Recruitment of eosinophils and increased expression of mast cells tryptase in the bronchial mucosa of patients with allergic asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 508s
Year: 2002

Pathophysiology of asthma
Source: ISSN=1025-448x, ISBN=1-904097-26-x, page=84
Year: 2003

Mast cells in COPD airways: relationship to bronchodilator responsiveness and angiogenesis
Source: Eur Respir J 2012; 39: 1361-1367
Year: 2012



Eosinophils promote airway smooth muscle cells differentiation to the contractile phenotype in asthma
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma
Year: 2019

Eosinophil subtypes’ effect on airway smooth muscle cells differentiation and migration in asthma
Source: Virtual Congress 2020 – Respiratory homeostasis and structural changes in disease
Year: 2020


LSC Abstract – Eosinophils enhance WNT-5a and TGF-β1 genes expression in airway smooth muscle cells and promote their proliferation in asthma
Source: International Congress 2016 – Clinical characteristics of asthma
Year: 2016