Source: Annual Congress 2009 - Treatment of lung cancer
Disease area: Thoracic oncology

Abstract

Introduction
Lung cancer is the leading cause of cancer-related death in both men and women in Europe. The overall 5-year survival rate is approximately 15% and this is partly due to the lack of early diagnosis. Non surgical treatment adds little in the overall survival.
Aim
The comparison of the survival rates between non small cell lung cancer (NSCLC) patients who received chemoradiotherapy versus those who received only chemotherapy.
Patients
We performed a retrospective analysis of patients with newly diagnosed NSCLC (stages IIIB – IV), who were admitted to our department between January 2003 and September 2008. We studied 99 patients: 88 males and 11 females. Their mean age (± SD) was: 63.9 ± 8.7 years.
Results
88 patients were current or ex-smokers and 11 non smokers. Mean tobacco consumption was 65.9 ± 35.4 pack/yrs. Heavy smokers (> 40 py) were especially males aged over 60. Fifty out of 99 patients had received radiotherapy and the mean survival rate (± SD) was 12.8 ± 9.9. Forty nine patients had not received radiotherapy and the mean survival rate (± SD) was 10.6 ± 9.3.
Conclusions
A small but clear benefit was observed in terms of survival in favor of patients who received the combination of radiotherapy and chemotherapy.

Rating:

Share or cite this content

Citations should be made in the following way:
G. Hillas, S. Nikolakopoulou, I. Kostara, H. Dimitropoulos, K. Sagris, P. Bakakos, F. Vlastos (Athens, Greece). Impact of radiotherapy on survival rates in chemotherapy treated non small cell lung cancer patients. Eur Respir J 2009; 34: Suppl. 53, 2643

Member's Comments

No comment yet.

Related content which might interest you: Impact of radiotherapy on survival rates in chemotherapy treated small cell lung cancer patients Source: Annual Congress 2009 - Treatment of lung cancer Year: 2009 Long-term survival of the patients with advanced non small cell lung carcinomas after induction chemotherapy Source: Eur Respir J 2005; 26: Suppl. 49, 78s Year: 2005 Rates of treatment response and median survival in advanced non small cell lung cancer patients Source: Eur Respir J 2004; 24: Suppl. 48, 302s Year: 2004 Outcome after pneumonectomy in non small cell lung cancer patients receiving a neoadjuvant therapy Source: Eur Respir J 2004; 24: Suppl. 48, 478s Year: 2004 Early concurrent chemoradiotherapy for limited small cell lung cancer (LSCLC). Analysis of toxicity and survival of 30 consecutive patients Source: Eur Respir J 2002; 20: Suppl. 38, 464s Year: 2002 Impact of neoadjuvant therapy on tumor resectability and survival of patients with locally advanced non-small cell lung cancer Source: Annual Congress 2011 - General thoracic surgery II Year: 2011 Comparison of quality of life in patients with non-small cell lung cancer treated by chemotherapy or radiotherapy Source: Eur Respir J 2004; 24: Suppl. 48, 75s Year: 2004 Influence of dose of radiotherapy on quality of life in patients with non-small cell lung cancer treated by radiotherapy Source: Eur Respir J 2005; 26: Suppl. 49, 495s Year: 2005 Tobacco exposure and survival in non small cell lung cancer patients treated with erlotinib Source: Annual Congress 2009 - Treatment of lung cancer Year: 2009 The 7-year results of the surgical treatment of non-small cell lung cancer (NSCLC) patients and the influence of neoadjuvant treatment Source: Annual Congress 2007 - Therapy of thoracic malignancies Year: 2007 Treatment of limited disease-small cell lung cancer Source: Eur Respir Mon; 2009: 44: 299–309 Year: 2009 Palliative treatment of locally advanced non small cell lung cancer with weekly fraction radiotherapy Source: Eur Respir J 2005; 26: Suppl. 49, 496s Year: 2005 Assessment of lung cancer related symptoms and chemotherapy related side effects in a group of patients with advanced lung cancer receiving palliative chemotherapy Source: Eur Respir J 2006; 28: Suppl. 50, 752s Year: 2006 Correlation between parameters of quality of life in patients with non-small cell lung cancer treated by chemotherapy and radiotherapy Source: Annual Congress 2007 - Therapeutic approaches in thoracic oncology Year: 2007 Symptomatic benefit of short regimen of palliative radiotherapy for elderly patients with locally advanced non small cell lung cancer Source: Annual Congress 2010 - Treatment of lung cancer Year: 2010 Respective indications of chemotherapy, radiotherapy and surgery in limited disease stage small cell lung carcinoma Source: Annual Congress 2005 - Neuroendocrine tumours of the lung Year: 2005 The effect on disease free survival of different regimens of chemotherapy (CT) in non small cell lung cancer (NSCLC) Source: Eur Respir J 2004; 24: Suppl. 48, 672s Year: 2004 Retrospective assessment of non small cell lung cancer stage IIIA-IIIB, treated with neoadjuvant chemotherapy Source: Annual Congress 2010 - Treatment of lung cancer Year: 2010 Survival outcomes of non small cell lung cancer (NSCLC) patients who are suitable for radical treatment at initial presentation Source: Annual Congress 2011 - Quality management for lung cancer patients Year: 2011 Evaluation of outpatient infections in lung cancer patients treated with chemotherapy and/or radiotherapy Source: Annual Congress 2012 - Screening, diagnosis, staging and treatment strategies for lung cancer Year: 2012