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Munich 2006
Monday 04.09.2006
Sarcoidosis
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Endobronchial involvement in patients with sarcoidosis
D. Attaran, M. Towhidi, A. Asnaashari, H. Rokni, E. Idani (Mashad, Ahvaz, Islamic Republic Of Iran)
Source:
Annual Congress 2006 - Sarcoidosis
Session:
Sarcoidosis
Session type:
Electronic Poster Discussion
Number:
3141
Disease area:
Interstitial lung diseases, Thoracic oncology
Abstract
Background : Sarcoidosis is a multiorgan granulomatous disorder of undetermined etiology with 90 % of patients exhibiting some degree of pulmonary involvement.
Transbronchial lung biopsy ( TBLB ) with fiberoptic bronchoscopy which demonstrate granuloma formation have been established as standard method for histologic confirmation of sarcoidosis. In this study endobronchial biopsy ( EBB ) was used to assess the frequency of positive EBB findings in patients with pulmonary sarcoidosis .
Methods : The study included 28 patients with sarcoidosis ( mean age 41.8 +_ 11.6 y and 55 % female ) TBLB and EBB were done for all cases.
Results : EBB was positive in 53.5 % of subjects and TBLB showed granuloma in 71.5 % of cases . In eight cases ( 28.5 % ) diagnosis was established only by EBB. Normal appearing endobronchial mucosa was seen in 73.5 % of patients with positive EBB findings.
Conclusion : Endobronchial involvement is common in sarcoidosis. EBB can safely increase the diagnostic value of fiberoptic bronchoscopy.
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D. Attaran, M. Towhidi, A. Asnaashari, H. Rokni, E. Idani (Mashad, Ahvaz, Islamic Republic Of Iran). Endobronchial involvement in patients with sarcoidosis. Eur Respir J 2006; 28: Suppl. 50, 3141
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