Increased T-regulatory cells within lymphocyte follicles in moderate COPD

Plumb J. , Smyth L. J. C. , Adams H. R. , Vestbo J. , Bentley A. , Singh S. D.

Source: Eur Respir J 2009; 34: 89-94
Journal Issue: July
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Plumb J. , Smyth L. J. C. , Adams H. R. , Vestbo J. , Bentley A. , Singh S. D.. Increased T-regulatory cells within lymphocyte follicles in moderate COPD. Eur Respir J 2009; 34: 89-94

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Significant increase of CD57+ cells in pulmonary lymphoid follicles of COPD patients
Source: Eur Respir J 2011; 37: 289
Year: 2011



Increased levels of CD4+CD25high and CD4+FoxP3+ T-regulatory cells (Tregs) in patients with different severity of bronchial asthma (BA)
Source: Annual Congress 2011 - Immunology and cell biology of asthma and COPD
Year: 2011

Reduced numbers of circulating CD4+CD25highFOXP3+ regulatory T cells in patients with allergic asthma
Source: Annual Congress 2008 - Understanding airway inflammation
Year: 2008


Increased expression of perforin in sputum CD8+ cells of smokers with COPD
Source: Eur Respir J 2001; 18: Suppl. 33, 365s
Year: 2001

Reduced bronchial CD4+ T cell activation in smokers with occupational asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 592s
Year: 2006

Langerhans-type, but not interstitial-type dendritic cells accumulate in current smokers and COPD patients
Source: Annual Congress 2009 - Pathology and immunology of COPD
Year: 2009


The declined CD4+ CD25+Treg cells in patients with moderate to severe asthma associated with over-expressed Th2 response
Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms
Year: 2012

Increased activation of T cells grown from endobronchial tissue of COPD current smokers
Source: Eur Respir J 2006; 28: Suppl. 50, 552s
Year: 2006

Enhanced expression of IL-18 and increased CD8+ T cells and eosinophils in the airways of asthma death
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


CD4+CD25+ T lymphocytes in patients with COPD
Source: Eur Respir J 2004; 24: Suppl. 48, 319s
Year: 2004

Apoptosis activated T- lymphocytes in induced sputum (IS) of patients with asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 596s
Year: 2004

Reduced numbers of bronchial mature dendritic cells in COPD
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008


Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD
Source: Eur Respir J 2010; 36: 781-791
Year: 2010



Increased T helper lymphocytes and macrophages in peripheral airways of patients with uncontrolled asthma
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


Recent thymic emigrants (RTEs) do not account for the increased number of T-cells seen in the lungs of patients with stable COPD compared to smokers with normal lung function and normal subjects
Source: Eur Respir J 2005; 26: Suppl. 49, 578s
Year: 2005

Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
Source: Eur Respir J 2001; 17: 946-953
Year: 2001



Decreased pulmonary mature dendritic cells in healthy smokers and smoking COPD patients
Source: Eur Respir J 2007; 30: Suppl. 51, 212s
Year: 2007

T regulatory cells within inflammatory foci of COPD lungs
Source: Annual Congress 2008 - Invasive and noninvasive measurements of lung inflammation
Year: 2008


Low number of regulatory T cells in bronchial asthma: association with inflammatory cytokines
Source: Annual Congress 2009 - Infections, immunity and inflammation
Year: 2009



Reduced intracellular IL-16 levels in CD8 lymphocytes residing in the lower airways of smokers
Source: Annual Congress 2009 - COPD and asthma - from the cell to the clinic
Year: 2009