Source: Annual Congress 2006 - COPD and inflammation
Disease area: Interstitial lung diseases

Abstract

Oral infections as in chronic periodontitis (CP) have been associated with chronic obstructive pulmonary disease (COPD) although no clear relationship has been established.
Objectives: The objective of the present study was to investigate the extent of periodontitis in a cohort of subjects with chronic respiratory insufficiency (CRI), using orthopantomograms (OPGs).
Methods: We studied all subjects (n=330) with CRI evaluated for lung transplantation at the Pulmonary Department at Rikshospitalet, Oslo, from 1990–2005. From 160 subjects with COPD (mean age 54.3 yrs, 43.8% men, and 99.4% former smokers) OPGs were available and compared to 88 subjects with CRI due to other diagnosis (mean age 46.0 yrs, 47.7% men, and 52.3% former smokers). This non-COPD group consists mainly of idiopathic pulmonary fibrosis (n=40), sarcoidosis (n=12), Eisenmenger syndrome (n=8), lymphangioleiomyomatosis (n=8) and primary pulmonary hypertension (n=6). The periodontal bone loss was measured from the cemento-enamel junction (CEJ) to the periodontal bone crest (PBC) on a maximum of 19 and a minimum of 4 (mean 8.4) proximal sites per person. The mean marginal bone level (MBL) per person was calculated.
Results: The mean MBL and the number of teeth between the groups differed. In the COPD group MBL was 3.9 mm vs. 2.4 mm in the non-COPD group (p<0.001). Number of remaining teeth in the COPD group was 16.7 ± 9.0 vs. 23.6 ± 5.9 in the non-COPD group (p<0.001). Conclusions: The present observations indicate that periodontitis is more common in subjects with COPD than non-COPD in a cohort with CRI. The data presented here are preliminary and have to bee further analyzed for confounding factors.

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Citations should be made in the following way:
I. Leuckfeld, M. V. Obregon-Whittle, I. Olsen, O. Geiran, O. Bjortuft (Oslo, Norway). Periodontitis and chronic obstructive pulmonary disease. Eur Respir J 2006; 28: Suppl. 50, 2000

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