Correlation between expression of p53, pRb, mdm2, p21WAF1/CIP1, PCNA, cyclin D1 and apoptotic index (AI) in non-small cell lung cancer (NSCLC) cells

D. Dworakowska, A. Karmolinski, E. Jassem, J. Jassem, M. Lapinski, D. Tomaszewski, J. Skokowski, K. Jaskiewicz, S. Yla-Herttuala, E. Czestochowska, K. Sworczak (Gdansk, Poland; Kuopio, Finland)

Source: Annual Congress 2006 - Molecular pathology and genetics of lung cancer
Session: Molecular pathology and genetics of lung cancer
Session type: Oral Presentation
Number: 1968
Disease area: Thoracic oncology

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. Dworakowska, A. Karmolinski, E. Jassem, J. Jassem, M. Lapinski, D. Tomaszewski, J. Skokowski, K. Jaskiewicz, S. Yla-Herttuala, E. Czestochowska, K. Sworczak (Gdansk, Poland; Kuopio, Finland). Correlation between expression of p53, pRb, mdm2, p21WAF1/CIP1, PCNA, cyclin D1 and apoptotic index (AI) in non-small cell lung cancer (NSCLC) cells. Eur Respir J 2006; 28: Suppl. 50, 1968

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
BAX and p16INK4A are independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer
Source: Eur Respir J 2002; 19: 134-140
Year: 2002



Expression of Fhit protein in non-small cell lung cancer (NSCLC) and its correlation with Ki-67, a proliferative marker
Source: Eur Respir J 2002; 20: Suppl. 38, 230s
Year: 2002

Adenovirus-mediated E2F-1 gene transfer in nonsmall-cell lung cancer induces cell growth arrest and apoptosis
Source: Eur Respir J 2002; 20: 703-709
Year: 2002



The prognostic value of altered pRb and p53 protein expression in non-small cell lung cancer
Source: Eur Respir J 2003; 22: Suppl. 45, 363s
Year: 2003

Expression of p53, Bcl-2 and Bax in non-small cell lung cancer
Source: Eur Respir J 2007; 30: Suppl. 51, 512s
Year: 2007

The role of HER-2/neu, p53, Bcl-2 and Ki-67 in patients with lung cancer
Source: International Congress 2019 – New molecular signatures in COPD, lung cancer and a1-antitrypsin deficiency
Year: 2019

Simultaneous assessment of p21/waf1, p53, pRb, mdm2 and cyclin D1in NSCLC cells
Source: Eur Respir J 2005; 26: Suppl. 49, 226s
Year: 2005

Therapy increases poly(ADP-ribose), p53 expression, p53-Ser392 –P, and p53-Ser2 –P levels in recurrent squamous cell lung cancer
Source: Eur Respir J 2002; 20: Suppl. 38, 14s
Year: 2002

Prognostic value of altered cyclin D1 expression in non-small cell lung cancer
Source: Eur Respir J 2004; 24: Suppl. 48, 673s
Year: 2004

Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells
Source: Eur Respir J 2004; 23: 665-670
Year: 2004



Apoptosis regulatory protein (p53, Bcl-2, survivin) expression in lung cancer-preliminary study
Source: Annual Congress 2008 - Novel trends in functional genomics and molecular pathology of neoplastic and non-neoplastic lung diseases
Year: 2008


The expression of Ki-67, a marker of proliferative activity, in resected nonsmall cell lung cancer
Source: Eur Respir J 2001; 18: Suppl. 33, 478s
Year: 2001

p53 and mdm2 expression in nonsmall cell lung cancer (NSCLC): the lack of prognostic relevance
Source: Eur Respir J 2001; 18: Suppl. 33, 230s
Year: 2001

FGFR1 gene aberrations and FGFR1 protein expression in squamous non-small cell lung cancer (Sq-NSCLC).
Source: Virtual Congress 2021 – Biology of lung cancer: preclinical and translational research
Year: 2021


Prognostic value of p21 protein expression in non-small cell lung cancer
Source: Eur Respir J 2004; 24: Suppl. 48, 674s
Year: 2004

Nuclear expression of Y-Box binding protein (YB-1) as a negative prognostic marker in non-small cell lung cancer
Source: Annual Congress 2003 - Lung cancer biology
Year: 2003


Prognostic significance and correlation between Akt phosphorylation and loss of PTEN protein expression in non-small cell lung cancer
Source: Eur Respir J 2005; 26: Suppl. 49, 458s
Year: 2005

Prognostic value of apoptotic index (AI) considered jointly with cell cycle regulators in non-small cell lung cancer (NSCLC)
Source: Eur Respir J 2006; 28: Suppl. 50, 387s
Year: 2006

Studies on clinical significance and relationship with PI and gene protein expression of p16, Rb and Cyclin-D1 in lung cancer
Source: Eur Respir J 2002; 20: Suppl. 38, 230s
Year: 2002

The association of p53 and p21 expression with clinicopathological parameters and prognosis in non-small cell lung cancer
Source: Annual Congress 2010 - Prognostic factors for lung cancer
Year: 2010