Source: Annual Congress 2006 - Pneumonia and other invasive pulmonary infections in children
Disease area: Respiratory infections

Abstract

Background. In Lithuania, the immunization coverage against pertussis is high. Nevertheless there is increase in pertussis cases.
The aim of study was to establish pertussis clinical presentation of children with confirmed pertussis who received 4 doses of pertussis whole-cell vaccine and compare this group with not vaccinated or not fully vaccinated (NVNFV) patients group.
Patients and Methods. 53 children with confirmed diagnosis of pertussis were observed. Children age was from 1 month to 15 years (average 7.5±5.4 y). 32 (60.4%) of 53 patients received complete vaccination against pertussis and 21 (39.6%) were not vaccinated or not fully vaccinated against pertussis. B.pertussis IgM and IgA antibodies were performed by ELISA (Labsystems, Finland).
Results. Only 8 (25%) of 32 fully vaccinated (FV) patients and 4 (19%) of 21 NVNFV were referred to the hospital with suspicion of pertussis. Patients in FV group tended to present with prolonged and paroxysmal cough (84.4%) whereas other pertussis symptoms in this group presented more rarely: whooping (28.1%), apnea (3.1%) and post-tussive vomiting (31.3%). The clinical presentation in NVNFV group included paroxysmal cough (95.2%), whooping (57.1%), apnea (28.5%) and post-tussive vomiting (55%).
Conclusions. Fully vaccinated children fell ill with pertussis at the median of 11 years old, 9 years following pertussis vaccination. Clinical presentation of pertussis is usually characterized by prolonged and paroxysmal cough in both groups whereas in FV children rarely by other classical symptoms like whooping, apnea and post-tussive vomiting.

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Citations should be made in the following way:
E. Kavaliunaite, I. Narkeviciute, G. Bernatoniene, R. Eidukevicius (Vilnius, Lithuania). Clinical manifestation of children pertussis in Lithuania. Eur Respir J 2006; 28: Suppl. 50, 1797

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