Source: Annual Congress 2008 - Physiological response to exercise performance
Disease area: Airway diseases

Abstract

Objective: To compare response to maximal and submaximal exercise tests between fatigue-limited (FL) vs. dyspnea-limited (DL) patients after training.
Methods: COPD patients according GOLD definition were included. They were classified as FL if they responded to maximal exercise test with fatigue Borg scale ≥ 2 points of difference vs. dyspnea Borg scale.As DL, if dyspnea score was ≥ 2 points vs. fatigue scale. We evaluated other exercise variables, SGRQ and 6 minute walking test. All patients were trained 8 weeks, three sessions/week, 90 min/session(strength and aerobic exercises).
Results:11 COPD patients were classified as DL and 14 as FT.

Table 1: Baseline Data and Post-training Exercise Response

	Fatigue limited patients (n=14)	Dyspnea limited patients (N=11)	p
Age,years	69.07 ± 8.04	66.66 ± 5.7	NS
Male/Female	8/6	8/3
FEV1postBD, %pred.	49 ± 8.9	49.5 ± 11.1	NS
FEV1/FVC	0.51 ± 0.06	0.49 ± 0.07	NS
BMI	23.97 ± 3.02	27.5 ± 3.6	0.011
Fatigue by Borg scale	6.07 ± 2.05	1.95 ± 1.23	0.0000058
Dyspnea by Borg scale	2.78 ± 1.36	4.36 ± 1.02	0.004
Post-training exercise response
Peak VO2, ml/kg/min	11.44 ± 4.6	9.6 ± 2.05	NS
WRMax,watts	48.71± 9.2	40.04 ± 15.48	0.033
6Minute Walking Test,m	505.42 ± 50.75	454.9 ± 6.43	0.048
Endurance Test,min	14.57 ± 9.55	6.71 ± 4.18	0.025
Delta SGRQ total score,units	-16.35 ± 27.63	-4.63 ± 7.69	NS

Other outcomes showed no differences between groups.
Conclusions: There´re not equal responses to training comparing FL vs. DL patients. FL patients had superior response in submaximal exercise tests and WRMax post-training.

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Citations should be made in the following way:
M. Sivori, M. Almeida, M. A. Barth (Buenos Aires, Argentina). Are fatigue-limited COPD patients better responders to exercise training than dyspnea-limited?. Eur Respir J 2008; 32: Suppl. 52, 3295

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