Source: Annual Congress 2006 - Pneumonia and other invasive pulmonary infections in children
Disease area: Respiratory infections

Abstract

The results of several studies have estimated the presents of epidemic cycle and seasonal variability of prevalence Chlamydophila. pneumoniae infection. The aim of the present research was studying endemic seasonal changes in prevalence C. pneumoniae in children of Siberia region (Novosibirsk). Serum samples were collected from children in the age of from 3 till 18 years with an infection of the up and low respiratory tract since January 2002 till January, 2005. In total 1838 children are surveyed. The specific C. pneumoniae IgG, M and A antibodies were determined by using immunofluorescence test.
After stratification by age and sex in each month in year, distinct peaks specific C. pneumoniae antibodies with prevalence 43,6% and 47,8% were noted in 2002 and 2004, whereas the lowest prevalence rate was seen in 2003 - 28,7%. The estimated year to year differences was statistical significant (p<0,01) and similar for both genders, but highest in primary school children. There was a pronounced seasonal variation in positive test results in Novosibirsk. The lowest rate of C. pneumoniae antibodies was marked in January and February, 2003: 11,7% and 12% (p <0,01). The maximal values are revealed in August 2002 (66,6%) and September 2004 (68%).
We suggested that C. pneumoniae is endemic in Siberia as it is in Western countries, and have trend to year-to-year variability and seasonality with a higher risk of acquisition infection during autumn.

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Citations should be made in the following way:
N. Kukhtinova, S. Krotov, V. Krotova (Novosibirsk, Russian Federation). Seroepidemiology of Chlamydophila pneumonia in children from the Siberia region (Novosibirsk). Eur Respir J 2006; 28: Suppl. 50, 1789

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