Cigarette smoke-induced airway neurogenic inflammation is mediated by α,ß-unsaturated aldehydes and the TRPA1 receptor.

R. Nassini, E. Andrè, B. Campi, S. Materazzi, M. Trevisani, S. Amadesi, D. Massi, C. Creminon, N. Vaksman, M. Civelli, N. Bunnett, P. Geppetti, R. Patacchini (Florence, Ferrara, Parma, Italy; San Francisco, CA, United States Of America; Gyf-sur-Yve

Source: Annual Congress 2008 - Recent advances in the pathogenesis and treatment of asthma and COPD
Session: Recent advances in the pathogenesis and treatment of asthma and COPD
Session type: Oral Presentation
Number: 4188
Disease area: Airway diseases

Congress or journal article abstractSlide presentationE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Nassini, E. Andrè, B. Campi, S. Materazzi, M. Trevisani, S. Amadesi, D. Massi, C. Creminon, N. Vaksman, M. Civelli, N. Bunnett, P. Geppetti, R. Patacchini (Florence, Ferrara, Parma, Italy; San Francisco, CA, United States Of America; Gyf-sur-Yve. Cigarette smoke-induced airway neurogenic inflammation is mediated by α,ß-unsaturated aldehydes and the TRPA1 receptor.. Eur Respir J 2008; 32: Suppl. 52, 4188

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation
Source: Eur Respir J 2015; 45: 1669-1680
Year: 2015



Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice
Source: Eur Respir J 2013; 42: 1677-1688
Year: 2013



TRPA1 mediates cigarette smoke-induced TNFa secretion in macrophages
Source: Virtual Congress 2021 – Environmental and lifestyle impacts on chronic lung disease
Year: 2021


Quercetin attenuates inflammation in cigarette smoke stimulated airway epithelial cells: Possible involvement of autophagy
Source: Annual Congress 2013 –New drugs in respiratory medicine
Year: 2013


The AMPK-TSC1/2-mTOR signaling pathway regulates cigarette smoking-induced inflammation and apoptosis in airway epithelial cells
Source: International Congress 2015 – Molecular pathways of lung injury due to tobacco-related products
Year: 2015


Role of highly reactive aldehydes in cigarette smoke induced airway inflammation
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011


Ceramide-1-phosphate attenuates cigarette smoke induce lung inflammation
Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation
Year: 2013


Cigarette smoke modulates rhinovirus-induced airway epithelial cell chemokine production
Source: Eur Respir J 2010; 35: 1256-1263
Year: 2010



Cryptotanshinone attenuates airway Inflammation induced by cigarette smoke in mice
Source: International Congress 2016 – New signalling pathways in COPD
Year: 2016

Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion
Source: ERJ Open Res, 7 (1) 00394-2020; 10.1183/23120541.00394-2020
Year: 2021



The role of microRNA-155 in cigarette smoke-induced inflammation.
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018



Involvement of neuropeptide and muscarinic receptor in pulmonary obstruction induced by cigarette smoke in mice
Source: Eur Respir J 2004; 24: Suppl. 48, 691s
Year: 2004

Propolis reverts cigarette smoke-induced emphysema through macrophage alternative activation
Source: International Congress 2017 – From the bench: therapeutic approaches in COPD and emphysema
Year: 2017


Mitochondria-targeted H2S suppresses and reverses cigarette smoke-induced inflammasome activity and lung injury in experimental COPD
Source: ERS Lung Science Conference 2020
Year: 2020

Cigarette smoke-induced emphysema occurs in the absence of TLR4-signalling in a murine model of COPD
Source: Annual Congress 2008 - Best of lung epithelial cells 2008
Year: 2008



Role of ß2-adrenergic receptor in cigarette smoke-induced COPD in mice
Source: International Congress 2018 – Functional genomics and COPD: new challenges
Year: 2018

Cigarette smoke-induced activation of the integrated stress response in COPD airway epithelial cells and the role of oxidative stress
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018

Tiotropium inhalation prevents acute cigarette smoke-induced airway inflammation in mice
Source: Annual Congress 2009 - Airway inflammation and host defence
Year: 2009

Aclidinium inhibits cigarette smoke-induced lung fibroblast-to-myofibroblast transition
Source: Eur Respir J 2013; 41: 1264-1274
Year: 2013