Source: Annual Congress 2008 - Factors related to outcome of community-acquired pneumonia
Disease area: Respiratory infections

Abstract

The PSI has been criticized for being an index that gives too much weight to age. Although it‘s a current opinion that the PSI might underestimate the severity of CAP in young patients, this hypothesis has not been yet tested. To study the ability of the PSI in predicting mortality and in deciding the site of care for young patients with CAP. A secondary analysis of the Community-Acquired Pneumonia Organization database was performed including adult patients hospitalized with CAP between Jan 2001 and Jan 2006. Two groups of patients were identified: those with ≤ 50 years of age, Group 1, and those with > 50 years, Group 2. Patients in PSI Risk Classes (RC) I-III were considered at low risk, while those in PSI RC IV-V at high risk. X² and ROC curve were used for statistical analysis. Among the 3,079 patients included in the study, 670 belonged to Group 1. In-hospital mortality of Group 1 is detailed in Figure 1, according to PSI RC.

The ROC curve corresponding to the logistic regression models with mortality of Group 1 as outcome and PSI RC as predictor showed a concordance index of 0.663. Even though the PSI gives a lot of points to age, physicians can safely use the PSI in predicting mortality and in deciding the site of care for young patients with CAP.

Rating:

Share or cite this content

Citations should be made in the following way:
V. Betti, S. Aliberti, P. Peyrani, P. Tarsia, F. Blasi, J. Ramirez (Milan, Italy; Louisville, KY, United States Of America). The pneumonia severity index (PSI) do not underestimate the severity of community-acquired pneumonia (CAP) in young patients: results from the CAPO international study. Eur Respir J 2008; 32: Suppl. 52, 1562

Member's Comments

No comment yet.

Related content which might interest you: Mortality directly related to community-acquired pneumonia (CAP) in hospitalized patients: results from the community-acquired pneumonia organization (CAPO) international cohort study Source: Annual Congress 2007 - Antibiotic treatment in community-acquired pneumonia Year: 2007 Is severity index enough to assess hospital admission of community-acquired pneumonia (CAP) patients? Source: Annual Congress 2006 - Evaluation of risk factors in community-acquired pneumonia Year: 2006 Physicians should not use the pneumonia severity index (PSI) or CRB-65 in deciding the need for hospitalization in cancer patients with community-acquired pneumonia (CAP) Source: Eur Respir J 2007; 30: Suppl. 51, 41s Year: 2007 Site of care for community-acquired pneumonia (CAP) patients with CRB-65 score of 0-1 and pneumonia severity index (PSI) risk class (RC) of IV-V: what to do when this discrepancy occurs. Results from the CAPO international study Source: Annual Congress 2008 - Treatment and outcome in hospitalised patients with community-acquired pneumonia Year: 2008 Use of pneumonia severity index in Spain to decide hospitalization among patients with community-acquired pneumonia (CAP). (Nacar Study) Source: Eur Respir J 2005; 26: Suppl. 49, 637s Year: 2005 Definition of severity and the reasons for hospitalization (RH) in patients with community-acquired pneumonia (CAP) Source: Eur Respir J 2005; 26: Suppl. 49, 641s Year: 2005 The presence of diabetes does not influence clinical outcomes in patients with community-acquired pneumonia: results from the community-acquired pneumonia organization (CAPO) international cohort study Source: Annual Congress 2007 - Severity scores and comorbidities in community-acquired pneumonia Year: 2007 Significant decrease in long-term survival for hospitalised patients with community-acquired pneumonia (CAP): results from the community-acquired pneumonia organisation (CAPO) international cohort study Source: Annual Congress 2009 - Impact of biomarkers in the management of community-acquired pneumonia Year: 2009 Patients‘ characteristics do not influence duration of antibiotic therapy (ABT) in hospitalized patients with community-acquired pneumonia (CAP): results from the CAPO international study Source: Annual Congress 2008 - Treatment and outcome in hospitalised patients with community-acquired pneumonia Year: 2008 Reasons that justify hospitalization for community-acquired pneumonia (CAP) patients with CURB-65 score 0-1 Source: Annual Congress 2008 - Treatment and outcome in hospitalised patients with community-acquired pneumonia Year: 2008 Does the use of the CURB-65 score improve outcomes in community-acquired pneumonia (CAP)? Source: Annual Congress 2009 - Pulmonary infections Year: 2009 Prevalence of hyponatremia (HN) in children with community acquired pneumonia (CAP) and its relation to disease severity, outcomes Source: Virtual Congress 2021 – Acute paediatric respiratory infections Year: 2021 A prospective study of the relationship of severity assessed by modified CURB-65 score and mortality in patients with commmunity acquired pneumonia (CAP) Source: Eur Respir J 2006; 28: Suppl. 50, 374s Year: 2006 Community-acquired pneumonia (CAP) in alcoholic patients (AL): differences in aetiology and severity Source: Eur Respir J 2002; 20: Suppl. 38, 560s Year: 2002 Community-acquired pneumonia (CAP) in the elderly: Prediction of mortality by physical symptoms, laboratory values and radiographic features on admission Source: Annual Congress 2010 - The spectrum of lower respiratory tract infections: risk factors of poor outcome and diagnostic tools Year: 2010 Clinical cure rates and infection types in the MOxifloxacin Treatment IV (MOTIV) study in hospitalized patients with community-acquired pneumonia (CAP) Source: Eur Respir J 2006; 28: Suppl. 50, 349s Year: 2006 Female gender is associated with poor clinical outcomes in hospitalized patients with community-acquired pneumonia: results from the CAPO international cohort study Source: Annual Congress 2008 - Treatment and outcome in hospitalised patients with community-acquired pneumonia Year: 2008 Community-acquired pneumonia (CAP): evaluation of severity criteria for hospitalization Source: Eur Respir J 2003; 22: Suppl. 45, 335s Year: 2003 The assessment of prognostic rules in patients with community-acquired pneumonia (CAP) Source: Eur Respir J 2003; 22: Suppl. 45, 149s Year: 2003 Correlation between pneumonia severity index and mortality within 30 days after the diagnosis of community-acquired pneumonia in elderly subjects Source: Eur Respir J 2006; 28: Suppl. 50, 741s Year: 2006