High proteasome activity and absence of NF-kB activation in cystic fibrosis cell culture and CF KO mouse models in response to oxidative stress Source: Eur Respir J 2005; 26: Suppl. 49, 403s Year: 2005
Differential expression of the S1P transporter, Spinster homologue 2 (Spns2), in airway epithelial cells and macrophages may drive defective macrophage function in COPD Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects Year: 2017
Fas activation impairs the alveolar epithelial function in mice by mechanisms involving apoptosis Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury Year: 2011
PTEN deficiency in alveolar type 2 cells accelerates cellular senescence, disrupts epithelial–mesenchymal and mitochondrial homeostasis, and induces age-related emphysema Source: International Congress 2019 – Cellular metabolism and immune senescence in lung pathology Year: 2019
Increased proliferation of type 2 alveolar epithelial cells in a pneumonectomy model mice with a deletion of p16ink4a gene. Source: International Congress 2018 – Regenerative and anti-fibrotic approaches Year: 2018
P2X7 receptor regulates cell survival, inflammation processes and proliferation of lung carcinoma cells Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease Year: 2019
Inhibition of insulin-like growth factor type I (IGF-I) gene in A549 human lung cancer cell line enhances cell apoptosis and causes phenotype changes relevant to increased tumor susceptibility to immune system Source: Eur Respir J 2007; 30: Suppl. 51, 715s Year: 2007
Novel functions of stanniocalcin-1 (STC1) through uncoupling protein 2 (UCP2) up-regulation; promoting survival of cancer cells under oxidative stress and inducing the uncoupling respiration (Warburg effect) Source: Annual Congress 2011 - Progress in pathology of lung cancer Year: 2011
Activation of Fas receptor impairs alveolar epithelial function in mouse lungs Source: Annual Congress 2010 - Emerging mechanisms in lung injury Year: 2010
Soluble biglycan promotes ovalbumin induced airway inflammation by modulating dendritic cell function in mice Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma Year: 2019
In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012
Transcriptomic profiling of alveolar type 2 cells from mice expressing an ILD associated SFTPCI73T mutation supports their role in inflammatory cell recruitment and fibrotic lung remodeling. Source: International Congress 2018 – Pulmonary fibrosis: from models to patients Year: 2018
Effect of hypoxia on gene regulation and differentiation in alveolar epithelial type II cells Source: Eur Respir J 2001; 18: Suppl. 33, 162s Year: 2001
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004
A549 cell promotes the proliferation and migration of fibroblast through FXR pathway Source: International Congress 2019 – Biology of lung cancer Year: 2019
Decreased expression of DNA synthesis repair recombination proteins in lungs of senescence accelerated mouse (SAM) Source: Eur Respir J 2003; 22: Suppl. 45, 73s Year: 2003
Effects of ASCL1 expression on tumorigenesis and immune cell infiltration in a syngenic mouse model of lung adenocarcinoma Source: International Congress 2019 – Biology of lung cancer Year: 2019
Calcium-sensing receptor (CaSR) drives lung ECM remodelling and fibrosis in murine asthma models and in ageing mice Source: International Congress 2019 – Airway inflammation: pharmacological mechanisms and novel targets Year: 2019
PAR-2 mediated interactions between mast cells and fibroblasts cause a switch in fibroblast morphology and cytokine profile Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis Year: 2019
Adult mice with a lung-specific inactivation of the transcription factor C/EBPα develop an emphysematic lung phenotype with impaired differentiation of the respiratory epithelium Source: Eur Respir J 2007; 30: Suppl. 51, 511s Year: 2007