Source: Annual Congress 2008 - Diagnosis of tuberculosis: problems and perspectives
Disease area: Respiratory critical care, Respiratory infections

Abstract

Introduction: Patients requiring intubation due to acute respiratory failure (ARF) may have different underlying pathophysiological abnormalities. Data comparing the incidence of VAP according to type of ARF is scarce.
Objective: To compare the incidence of VAP in patients requiring intubation due to ARF associated with medical conditions, neurological conditions, or trauma/surgery.
Methods: A total of 168 consecutive ventilated patients were studied from 11/08 to 2/09. Type of ARF was classified as associated with medical conditions (ARF-MC), associated with neurological conditions (ARF-NC), or associated with trauma and/or major surgery (ARF-TS). Incidence was calculated using 1,000 ventilator-days and compared using Z-statistics.
Results: The incidence of VAP for patients with ARF-MC was 9/1000 vent-days; for patients with ARF-NC was 24/1000 vent-days; and for patients with ARF-TS was 34/1000 vent-days. A statistically significant difference was found in patients with ARF-TS when compared to patients with ARF-MC (P=0.003)
Conclusions: Incidence of VAP is significantly higher in patients with respiratory failure associated with trauma and/or major surgery. This data highlights the need for developing specific VAP preventive strategies for patients with trauma-related respiratory failure.

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Citations should be made in the following way:
I. Smith, D. McLeod, T. Blackam, J. Nation, N. Baker, A. Davies (Birmingham, West Midlands, United Kingdom). Is ²blind² pleural biopsy still of value in tuberculous effusions?. Eur Respir J 2008; 32: Suppl. 52, 2392

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