Superoxide generation in pulmonary and systemic arterial smooth muscle cells and fibroblasts under hypoxic conditions

B. Fuchs, B. Ahmet, E. Bakytbek, R. Markus, S. Natascha, R. T. Schermuly, G. Hossein A., S. Werner, G. Friedrich, W. Norbert (Giessen, Germany)

Source: Annual Congress 2008 - Pathophysiology of pulmonary hypertension
Session: Pathophysiology of pulmonary hypertension
Session type: E-Communication Session
Number: 282
Disease area: Pulmonary vascular diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
B. Fuchs, B. Ahmet, E. Bakytbek, R. Markus, S. Natascha, R. T. Schermuly, G. Hossein A., S. Werner, G. Friedrich, W. Norbert (Giessen, Germany). Superoxide generation in pulmonary and systemic arterial smooth muscle cells and fibroblasts under hypoxic conditions. Eur Respir J 2008; 32: Suppl. 52, 282

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Proliferative hypoxic response of pulmonary artery smooth muscle cells: the fibroblasts role
Source: Eur Respir J 2007; 30: Suppl. 51, 510s
Year: 2007

Redox state of mitochondrial cytochromes in isolated lungs and pulmonary arterial smooth muscle cells during acute and prolonged hypoxia
Source: Annual Congress 2007 - Cellular and molecular aspects of pulmonary hypertension
Year: 2007


Increased generation of reactive oxygen species in pulmonary arterial smooth muscle cells, isolated from monocrotaline-treated rats
Source: Annual Congress 2009 - Pathobiology of pulmonary vascular diseases
Year: 2009


Caspase-1 triggers smooth muscle cell proliferation in hypoxic pulmonary hypertension
Source: International Congress 2019 – Pulmonary hypertension: novelties from the bench
Year: 2019


Dexamethasone induces anti-remodelling effects in rat pulmonary arterial smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and cell biology
Year: 2012


Hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: possible mechanisms
Source: Eur Respir J 2004; 24: Suppl. 48, 561s
Year: 2004

Apoptosis and cell proliferation in chronic hypoxic pulmonary hypertension
Source: Lung Science Conference 2007 - Translational research in pulmonary disease: Hypoxia-driven mechanisms
Year: 2007


The effects of hypoxia on the cells of the pulmonary vasculature
Source: Eur Respir J 2007; 30: 364-372
Year: 2007



Hypoxia-induced increase in NO production and eNOS expression by murine pulmonary microvascular endothelial cells
Source: Annual Congress 2006 - Pulmonary circulation: inflammation and remodelling
Year: 2006


CCR2/CCR5-mediated macrophage–smooth muscle cell crosstalk in pulmonary hypertension
Source: Eur Respir J, 54 (4) 1802308; 10.1183/13993003.02308-2018
Year: 2019



Effect of hypoxia on proliferation and VEGF-release of human bronchial smooth muscle cells
Source: Annual Congress 2013 –Novel in vitro and animal models to study lung diseases
Year: 2013

Shroom expression is attenuated in pulmonary arterial hypertension
Source: Eur Respir J 2008; 32: 871-880
Year: 2008



The role of superoxide in hypoxic pulmonary vasoconstriction in chronically hypoxic rat lungs
Source: Eur Respir J 2004; 24: Suppl. 48, 95s
Year: 2004

Increased p130Cas activity induces smooth muscle cell proliferation and migration in idiopathic pulmonary arterial hypertension
Source: Annual Congress 2011 - Experimental pulmonary hypertension
Year: 2011


Role of endothelial and smooth muscle cells in vascular wall remodeling of large pulmonary arteries in patients with CTEPH
Source: Annual Congress 2007 - Venous thromboembolic disease
Year: 2007


Alkalosis induce eNOS activation in human pulmonary arterial endothelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 73s
Year: 2001

Mir-17 modulates smooth muscle cell markers, apoptosis and BMPR-II levels in human pulmonary artery smooth muscle cells
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Involvement of pulmonary artery smooth muscle cell apoptosis in simvastatin-induced regression of hypoxic pulmonary hypertension
Source: Annual Congress 2008 - Pathophysiology of pulmonary hypertension
Year: 2008


Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells - role of hypoxia-inducible transcription factors
Source: Eur Respir J 2001; 18: Suppl. 33, 159s
Year: 2001

Regulation of connexins by hypoxia in rat pulmonary vascular cells in an in vitro model of pulmonary hypertension
Source: International Congress 2017 – Experimental PH
Year: 2017